MABN844MI

MilliporeSigma™ Mouse anti-Neurophysin 1, Clone: PS 38,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABN844MI-Each-of-1 In Stock ₹ 38,734.72

MABN844MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

Neurophysin 1

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

Oxt; Ot

Immunogen

KLH-conjugated acid soluble extract of rat (Sprague-Dawley) intermediate lobes corresponding to rat Neurophysin 1.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_037128

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2b κ

Applications

Western Blot

Clone

PS 38

Gene Accession No.

P01179

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Rat

Form

Purified

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Description

  • Specifically detects Neurophysin 1 clone: PS 38 in Rat samples, and it is validated for Western Blotting Neurophysins are linear cycteine-rich proteins containing 93-95 amino acids
  • Two types of neurophysins, NPI and NPII are found in most mammalian species and they serve as carriers of oxytocin (OT) and vasopressin (AVP), respectively
  • Each NP and its associated hormone is synthesized as one precursor protein, OT-NPI (UniProt P01179) encoded by the Oxt (or Ot) gene or VAP-NPII (UniProt P01186) encoded by the Avp gene in rat species
  • Post-translational cleavages remove the signal peptide and process the precursor into mature OT and NPI (aa 20-28 and aa 32-135, respectively, of OT-NPI), or AVP and NPII (aa 24-32 and aa 36-128, respectively, of AVP-NPII)
  • OT is a potent hormone and neurotransmitter secreted within the pituitary gland
  • OT exerts its biological activity through its receptor OXTR (also known as OTR)
  • OT is used clinically for labor induction and may exhibit therapeutic potential for treating social anxiety disorders
  • VAP functions primarily as an anti-diuretic and regulates the concentration of water, glucose, and salts in blood
  • VAP is secreted from the posterior pituitary, but exerts its biological activity in the kidney via the G protein-coupled receptor AVPR2 (V2R).

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MilliporeSigma™

MABN844MI

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Antigen:
Neurophysin 1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Oxt; Ot

Immunogen:
KLH-conjugated acid soluble extract of rat (Sprague-Dawley) intermediate lobes corresponding to rat Neurophysin 1.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_037128

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
Western Blot

Clone:
PS 38

Gene Accession No.:
P01179

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Rat

Form:
Purified

Img

MilliporeSigma™

MABN845MI

--


Antigen:
Neurophysin 2/NP-AVP

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Avp

Immunogen:
KLH-conjugated acid soluble extract of rat (Sprague-Dawley) intermediate lobes.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_058688

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG2b κ

Applications:
Immunoassay, ELISA, Immunohistochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot

Clone:
PS 41

Gene Accession No.:
P01186

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Rat

Form:
Purified

Img

MilliporeSigma™

MABN851MI

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Antigen:
CRALBP

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
RLBP1, CRALBP

Immunogen:
GST-tagged recombinant protein corresponding to the N-terminal half of human CRALBP.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000317

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
3H9.1

Gene Accession No.:
P12271

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

Img

Fischer Scientific

MABN852-100

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Antigen:
APP

Classification:
Monoclonal

Formulation:
__

Gene Symbols:
APP,A4,AD1

Immunogen:
A linear peptide corresponding to 15 amino acids from the C-terminal region of human Amyloid-beta A4 protein.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000475

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Isotype:
IgG1 κ

Applications:
ELISA, Immunocytochemistry, Inhibition Assays, Western Blot

Clone:
2B3

Gene Accession No.:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse, Human

Form:
Purified