MABN845MI
MilliporeSigma™ anti-Neurophysin 2/NP-AVP Clone: PS 41,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN845MI-Each-of-1 | In Stock | ₹ 45,381.02 |
MABN845MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,381.02
GST (18%): ₹ 8,168.584
Total Price: ₹ 53,549.604
Antigen
Neurophysin 2/NP-AVP
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P01186
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone PS 41 reacts with Vasopressin-neurophysin 2-copeptin precursor, neurophysin 2, but not Arg-vasopressin, copeptin, oxytocin, or neurophysin 1.
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG2b κ
Applications
Immunoassay, ELISA, Immunohistochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot
Clone
PS 41
Formulation
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
Avp
Immunogen
KLH-conjugated acid soluble extract of rat (Sprague-Dawley) intermediate lobes.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_058688
Target Species
Rat
Form
Purified
Related Products
Description
- Specifically detects Neurophysin 2/NP-AVP Clone: PS 41 in Rat samples, and it is validated for Electron Microscopy, ELISA, Immunohistochemistry, Immunoprecipitation, Radioimmunoassay, Western Blotting The neurophysin 1 and 2 (NPI and NPII) are carriers of peptide hormone oxytocin (OT) and vasopressin (AVP), respectively
- Each NP and its associated hormone peptide are synthesized as one precursor protein, OT-NPI (UniProt P01179) encoded by the Oxt (or Ot) gene or AVP-NPII (UniProt P01186) encoded by the Avp gene in rat species
- Post-translational cleavages remove the signal peptide and process the precursor into mature OT and NPI (aa 20-28 and aa 32-135, respectively, of OT-NPI) or AVP and NPII (aa 24-32 and aa 36-128, respectively, of AVP-NPII)
- OT is a potent hormone and neurotransmitter secreted within the pituitary gland
- OT exerts its biological activity through its receptor OXTR (also known as OTR)
- OT is used clinically for labor induction and may exhibit therapeutic potential for treating social anxiety disorders
- AVP functions primarily as an anti-diuretic and regulates the concentration of water, glucose, and salts in blood
- AVP is secreted from the posterior pituitary, but exerts its biological activity in the kidney via the G protein-coupled receptor AVPR2 (V2R).
Compare Similar Items
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Antigen: Neurophysin 2/NP-AVP
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P01186
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone PS 41 reacts with Vasopressin-neurophysin 2-copeptin precursor, neurophysin 2, but not Arg-vasopressin, copeptin, oxytocin, or neurophysin 1.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG2b κ
Applications: Immunoassay, ELISA, Immunohistochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot
Clone: PS 41
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Avp
Immunogen: KLH-conjugated acid soluble extract of rat (Sprague-Dawley) intermediate lobes.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_058688
Target Species: Rat
Form: Purified
Antigen:
Neurophysin 2/NP-AVP
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P01186
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone PS 41 reacts with Vasopressin-neurophysin 2-copeptin precursor, neurophysin 2, but not Arg-vasopressin, copeptin, oxytocin, or neurophysin 1.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG2b κ
Applications:
Immunoassay, ELISA, Immunohistochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot
Clone:
PS 41
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Avp
Immunogen:
KLH-conjugated acid soluble extract of rat (Sprague-Dawley) intermediate lobes.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_058688
Target Species:
Rat
Form:
Purified
Antigen: CRALBP
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P12271
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Western Blot
Clone: 3H9.1
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: RLBP1, CRALBP
Immunogen: GST-tagged recombinant protein corresponding to the N-terminal half of human CRALBP.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_000317
Target Species: Mouse
Form: Purified
Antigen:
CRALBP
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P12271
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
3H9.1
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
RLBP1, CRALBP
Immunogen:
GST-tagged recombinant protein corresponding to the N-terminal half of human CRALBP.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_000317
Target Species:
Mouse
Form:
Purified
Antigen: APP
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 2B3 specifically detects Amyloid-beta A4 protein in human and murine neurons. It targets an epitope within 15 amino acids including the beta-secretase cleavage site.
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG1 κ
Applications: ELISA, Immunocytochemistry, Inhibition Assays, Western Blot
Clone: 2B3
Formulation: __
Gene Symbols: APP,A4,AD1
Immunogen: A linear peptide corresponding to 15 amino acids from the C-terminal region of human Amyloid-beta A4 protein.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_000475
Target Species: Mouse, Human
Form: Purified
Antigen:
APP
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 2B3 specifically detects Amyloid-beta A4 protein in human and murine neurons. It targets an epitope within 15 amino acids including the beta-secretase cleavage site.
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG1 κ
Applications:
ELISA, Immunocytochemistry, Inhibition Assays, Western Blot
Clone:
2B3
Formulation:
__
Gene Symbols:
APP,A4,AD1
Immunogen:
A linear peptide corresponding to 15 amino acids from the C-terminal region of human Amyloid-beta A4 protein.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_000475
Target Species:
Mouse, Human
Form:
Purified
Antigen: APP
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 2B3 specifically detects Amyloid-beta A4 protein in human and murine neurons. It targets an epitope within 15 amino acids including the beta-secretase cleavage site.
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG1 κ
Applications: ELISA, Immunocytochemistry, Inhibition Assays, Western Blot
Clone: 2B3
Formulation: __
Gene Symbols: APP,A4,AD1
Immunogen: A linear peptide corresponding to 15 amino acids from the C-terminal region of human Amyloid-beta A4 protein.
Quantity: 25 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_000475
Target Species: Mouse, Human
Form: Purified
Antigen:
APP
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 2B3 specifically detects Amyloid-beta A4 protein in human and murine neurons. It targets an epitope within 15 amino acids including the beta-secretase cleavage site.
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG1 κ
Applications:
ELISA, Immunocytochemistry, Inhibition Assays, Western Blot
Clone:
2B3
Formulation:
__
Gene Symbols:
APP,A4,AD1
Immunogen:
A linear peptide corresponding to 15 amino acids from the C-terminal region of human Amyloid-beta A4 protein.
Quantity:
25 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_000475
Target Species:
Mouse, Human
Form:
Purified