MABC953MI

MilliporeSigma™ Rat anti-Prohibitin-2/PHB2, Clone: 7F8E3,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABC953MI-Each-of-1 In Stock ₹ 41,307.51

MABC953MI - Each of 1

₹ 41,307.51

In Stock

Quantity

1

Base Price: ₹ 41,307.51

GST (18%): ₹ 7,435.352

Total Price: ₹ 48,742.862

Antigen

Prohibitin-2/PHB2

Classification

Monoclonal

Formulation

Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

PHB2; BAP; REA

Immunogen

KLH-conjugated linear peptide corresponding to human Prohibitin-2/PHB2.

Quantity

100 μg

Research Discipline

Apoptosis, Cancer

Gene ID (Entrez)

NP_001138303

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2a κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

7F8E3

Gene Accession No.

Q99623

Host Species

Rat

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Monkey, Mouse, Rat

Form

Purified

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Description

  • Specifically detects Prohibitin-2/PHB2 clone: 7F8E3 in Human, Monkey, Mouse, Rat samples, and it is validated for Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blotting Prohibitin-2 (UniProt Q99623; also known as B-cell associated protein, B-cell receptor-associated protein BAP37, BCAP37, D-prohibitin, PHB2, Repressor of estrogen receptor activity) is encoded by the PHB2 (also known as BAP, REA) gene (Gene ID 11331) in human
  • Prohibitins are assembled into a ring-like PHB complex with 16-20 alternating Phb1 and Phb2 subunits in the inner mitochondrial membrane, where they function as chaperone for respiration chain proteins or as important structural scaffold for optimal mitochondrial morphology and function
  • Prohibitins are also reported to modulate transcriptions by interacting with various transcription factors, including nuclear receptors
  • Upregulated expression of prohibitins, septin 9, neurabin 1, and other cytoskeletal and functional proteins is found at the glutathione S-transferase placental-form-positive (GST-P+) hepatocellular carcinoma (HCC) foci during initiation and/or promotion stages of rat hepatocarcinogenesis, implicating an involvement of prohibitins in the neoplastic transformation of rat liver preneoplastic lesions.

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MABC953MI

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Antigen:
Prohibitin-2/PHB2

Classification:
Monoclonal

Formulation:
Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
PHB2; BAP; REA

Immunogen:
KLH-conjugated linear peptide corresponding to human Prohibitin-2/PHB2.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_001138303

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
7F8E3

Gene Accession No.:
Q99623

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Monkey, Mouse, Rat

Form:
Purified

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MilliporeSigma™

MABC954

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Antigen:
MUTYH

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
MUTYH; MYH

Immunogen:
GST-tagged recombinant internal fragment from the N-terminal half of human MUTYH.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_036354

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
12D5.1

Gene Accession No.:
Q9UIF7

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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Antigen:
__

Classification:
__

Formulation:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
__

Isotype:
__

Applications:
__

Clone:
__

Gene Accession No.:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Target Species:
__

Form:
__

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Antigen:
CD1d

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2aκ antibody in PBS without preservatives.

Gene Symbols:
CD1d, Cd1d1

Immunogen:
Rat CD1d-transduced M12.4.1.C3 cells.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_058775

Content And Storage:
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Isotype:
IgG2a κ

Applications:
Functional Assay, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
WTH-1

Gene Accession No.:
Q63493

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Form:
Purified