MABS83125UG
PI3 Kinase, Mouse anti-Mouse, Human, Clone: 1D5.1, Millipore Sigma™
Manufacturer: MilliporeSigma
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS83125UG-Each-of-1 | In Stock | ₹ 16,456.61 |
MABS83125UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
PI3 Kinase
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
PIK3R1;GRB1
Immunogen
GST/His-tagged recombinant fragment corresponding to 77 amino acids from the N-terminal region of the p85 regulatory subunit of human PI 3-kinase alpha.
Quantity
25 μg
Research Discipline
Signaling
Test Specificity
Clone 1D5.1 detects p85 subunit of human and murine PI-3 kinase alpha. It targets an epitope within 77 amino acids from the N-terminal region.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Isotype
IgG2b κ
Applications
Western Blot
Clone
1D5.1
Dilution
Western Blotting Analysis: 0.5μg/mL from a representative lot detected PI3 Kinase, p85, N-SH3 in 10μg of human cerebral cortex tissue lysate.
Gene Alias
Phosphatidylinositol 3-kinase regulatory subunit alpha;Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;PI3-kinase regulatory subunit alpha;PtdIns-3-kinase regulatory subunit p85-alpha;PI3-kinase subunit p85-alpha;PI3K regulatory subunit alpha;PtdIns-3-kinase regulatory subunit alpha
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Mouse, Human
Form
Purified
Description
- Anti-PI3 Kinase, p85, N-SH3, clone 1D5.1, Cat
- No
- MABS831, is a mouse monoclonal antibody that detects human and murine p85 subunit of PI3 kinase
- It has been tested for use in Western Blotting
- Phosphatidylinositol 3-kinase regulatory subunit alpha (UniProt: P27986; also known as Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PtdIns-3-kinase regulatory subunit p85-alpha, PI3-kinase subunit p85-alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha) is encoded by the PIK3R1 (also known as GRB1) gene (Gene ID: 5295) in human
- PI3K regulatory subunit alpha catalyzes the phosphorylation of PI(4,5)P2 inositol ring at the 3 position to generate PI(3,4,5)P3, a potent second messenger that mediates survival signaling and insulin action
- PI3 Kinase is a heterodimeric complex composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit
- Following ligand binding, tyrosine phosphorylation of growth factor receptors creates docking sites for p85 binding (through its SH2 domains), and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane
- PI3 kinase alpha plays a role in insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues
- Mutations in PIK3R1 gene are known to be associated with insulin resistance.
Compare Similar Items
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Antigen: PI3 Kinase
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: PIK3R1;GRB1
Immunogen: GST/His-tagged recombinant fragment corresponding to 77 amino acids from the N-terminal region of the p85 regulatory subunit of human PI 3-kinase alpha.
Quantity: 25 μg
Research Discipline: Signaling
Test Specificity: Clone 1D5.1 detects p85 subunit of human and murine PI-3 kinase alpha. It targets an epitope within 77 amino acids from the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: 1D5.1
Dilution: Western Blotting Analysis: 0.5μg/mL from a representative lot detected PI3 Kinase, p85, N-SH3 in 10μg of human cerebral cortex tissue lysate.
Gene Alias: Phosphatidylinositol 3-kinase regulatory subunit alpha;Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;PI3-kinase regulatory subunit alpha;PtdIns-3-kinase regulatory subunit p85-alpha;PI3-kinase subunit p85-alpha;PI3K regulatory subunit alpha;PtdIns-3-kinase regulatory subunit alpha
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Human
Form: Purified
Antigen:
PI3 Kinase
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
PIK3R1;GRB1
Immunogen:
GST/His-tagged recombinant fragment corresponding to 77 amino acids from the N-terminal region of the p85 regulatory subunit of human PI 3-kinase alpha.
Quantity:
25 μg
Research Discipline:
Signaling
Test Specificity:
Clone 1D5.1 detects p85 subunit of human and murine PI-3 kinase alpha. It targets an epitope within 77 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
1D5.1
Dilution:
Western Blotting Analysis: 0.5μg/mL from a representative lot detected PI3 Kinase, p85, N-SH3 in 10μg of human cerebral cortex tissue lysate.
Gene Alias:
Phosphatidylinositol 3-kinase regulatory subunit alpha;Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;PI3-kinase regulatory subunit alpha;PtdIns-3-kinase regulatory subunit p85-alpha;PI3-kinase subunit p85-alpha;PI3K regulatory subunit alpha;PtdIns-3-kinase regulatory subunit alpha
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Human
Form:
Purified
Antigen: PI3 Kinase
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: PIK3R1,GRB1
Immunogen: GST/His-tagged recombinant fragment corresponding to 77 amino acids from the N-terminal region of the p85 regulatory subunit of human PI 3-kinase alpha.
Quantity: 100 μg
Research Discipline: Signaling
Test Specificity: Clone 1D5.1 detects p85 subunit of human and murine PI-3 kinase alpha. It targets an epitope within 77 amino acids from the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: 1D5.1
Dilution: __
Gene Alias: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Human
Form: Purified
Antigen:
PI3 Kinase
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
PIK3R1,GRB1
Immunogen:
GST/His-tagged recombinant fragment corresponding to 77 amino acids from the N-terminal region of the p85 regulatory subunit of human PI 3-kinase alpha.
Quantity:
100 μg
Research Discipline:
Signaling
Test Specificity:
Clone 1D5.1 detects p85 subunit of human and murine PI-3 kinase alpha. It targets an epitope within 77 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
1D5.1
Dilution:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Human
Form:
Purified
Antigen: __
Classification: __
Conjugate: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Test Specificity: __
Content And Storage: __
Isotype: __
Applications: __
Clone: __
Dilution: __
Gene Alias: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Conjugate:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Applications:
__
Clone:
__
Dilution:
__
Gene Alias:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Target Species:
__
Form:
__
Antigen: EGFR
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse IgG2bκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant human EGFR fragment correspoding to a cytoplasmic region C-terminal to the kinase domain.
Quantity: 50 μg
Research Discipline: Signaling
Test Specificity: Epitope region is present in spliced isoform 1 (p170), but not in isoform 2 (p60, Truncated, TEGFR), isoform 3 (p110) or isoform 4 reported by UniProt (P00533).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Immunocytochemistry, Western Blot
Clone: 7F12.1
Dilution: __
Gene Alias: __
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
EGFR
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse IgG2bκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant human EGFR fragment correspoding to a cytoplasmic region C-terminal to the kinase domain.
Quantity:
50 μg
Research Discipline:
Signaling
Test Specificity:
Epitope region is present in spliced isoform 1 (p170), but not in isoform 2 (p60, Truncated, TEGFR), isoform 3 (p110) or isoform 4 reported by UniProt (P00533).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Immunocytochemistry, Western Blot
Clone:
7F12.1
Dilution:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified