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MABT132225

GCP2, Mouse anti-Mouse, Chicken, Human, Frog, Fish, Clone: GCP2-02, Millipore Sigma™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MABT132225-Each-of-1 In Stock ₹ 16,456.61

MABT132225 - Each of 1

₹ 16,456.61

In Stock

Quantity

1

Base Price: ₹ 16,456.61

GST (18%): ₹ 2,962.19

Total Price: ₹ 19,418.80

Antigen

GCP2

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols

Tubgcp2;Gcp2

Immunogen

GST-tagged recombinant fragment corresponding to the first 194 amino acids from the N-terminal region of murine Gamma-tubulin complex component 2.

Quantity

25 μg

Research Discipline

Cell Structure

Gene ID (Entrez)

NP_001272936.1

Target Species

Mouse, Chicken, Human, Frog, Fish

Form

Purified

Applications

ELISA, Immunocytochemistry, Immunomicroscopy, Immunoprecipitation, Western Blot

Clone

GCP2-02

Dilution

Western Blotting Analysis: 1μg/mL from a representative lot detected GCP2 in human glioblastoma T98G cell lysate.Immunoprecipitation Analysis: A representative lot immunoprecipitated GCP2 in Immunoprecipitation applications (Draberova, E., et. al. (2015). J Neuropathol Exp Neurol. 74(7):723-42).Immunocytochemistry Analysis: A representative lot detected GCP2 in Immunocytochemistry applications (Draberova, E., et. al. (2015). J Neuropathol Exp Neurol. 74(7):723-42).Western Blotting Analysis: A representative lot detected GCP2 in Western Blotting applications (Draberova, E., et. al. (2015). J Neuropathol Exp Neurol. 74(7):723-42).ELISA Analysis: A representative lot detected GCP2 in ELISA applications (Draberova, E., et. al. (2015). J Neuropathol Exp Neurol. 74(7):723-42).Electron Microscopy Analysis: A representative lot detected GCP2 in Electron Microscopy applications (Draberova, E., et. al. (2015). J Neuropathol Exp Neurol. 74(7):723-42). Immunoprecipitation Analysis: A represneta

Gene Alias

Gamma-tubulin complex component 2

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone GCP2-02 specifically detects GCP2 in T98G glioblastoma cells. It targets an epitope within 12 amino acids from the N-terminal region.

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Anti-GCP2, clone GCP2-02, Cat
  • No
  • MABT1322, is a mouse monoclonal antibody that detects Gamma-tubulin complex component 2 (CGP2) and has been tested for use in ELISA, Electron Microscopy, Immunocytochemistry, Immunoprecipitation, and Western Blotting
  • Gamma-tubulin complex component 2 (UniProt: Q921G8; also known as GCP2) is encoded by the Tubgcp2 (also known as Gcp2) gene (Gene ID: 74237) in murine species
  • Gamma-tubulin complex that is essential for microtubule nucleation at the centrosome is composed of gamma-tubulin, GCP2, GCP3, GCP4, GCP5 and GCP6
  • GCPs are characterized by sequence homology in two specific regions known as the grip1 and grip2 motifs
  • GPCs associate with gamma-tubulin to form a V-shaped subcomplex known as gamma-tubulin small complex
  • In this complex GCPs 2 and 3 interact via their N-terminal domain and form the arms of the V
  • The two-distal part of the V (C-terminal domains) bind to gamma-tubulin
  • The gamma-tubulin complex serves as a template for polarized growth and regulation of microtubules in eukaryotes
  • Significantly higher expression of both GPC2 and 3 have been reported in glioblastoma cells and they are concentrated I the centrosomes in interphase glioblastoma cells
  • Depletion of GPC2 and 3 causes accumulation of cells in G2/M and result in mitotic delay
  • (Ref.: Farache, D., et al
  • (2016)
  • J
  • Biol
  • Chem
  • 291(44); 23112-25; Draberova, E., et al
  • (2015)
  • J
  • Neuropathol
  • Exp
  • Neurol
  • 74(7); 723-42).

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Show Difference

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Fischer Scientific

MABT132225

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Antigen:
GCP2
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
Tubgcp2;Gcp2
Immunogen:
GST-tagged recombinant fragment corresponding to the first 194 amino acids from the N-terminal region of murine Gamma-tubulin complex component 2.
Quantity:
25 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001272936.1
Target Species:
Mouse, Chicken, Human, Frog, Fish
Form:
Purified
Applications:
ELISA, Immunocytochemistry, Immunomicroscopy, Immunoprecipitation, Western Blot
Clone:
GCP2-02
Dilution:
Western Blotting Analysis: 1μg/mL from a representative lot detected GCP2 in human glioblastoma T98G cell lysate.Immunoprecipitation Analysis: A representative lot immunoprecipitated GCP2 in Immunoprecipitation applications (Draberova, E., et. al. (2015). J Neuropathol Exp Neurol. 74(7):723-42).Immunocytochemistry Analysis: A representative lot detected GCP2 in Immunocytochemistry applications (Draberova, E., et. al. (2015). J Neuropathol Exp Neurol. 74(7):723-42).Western Blotting Analysis: A representative lot detected GCP2 in Western Blotting applications (Draberova, E., et. al. (2015). J Neuropathol Exp Neurol. 74(7):723-42).ELISA Analysis: A representative lot detected GCP2 in ELISA applications (Draberova, E., et. al. (2015). J Neuropathol Exp Neurol. 74(7):723-42).Electron Microscopy Analysis: A representative lot detected GCP2 in Electron Microscopy applications (Draberova, E., et. al. (2015). J Neuropathol Exp Neurol. 74(7):723-42). Immunoprecipitation Analysis: A represneta
Gene Alias:
Gamma-tubulin complex component 2
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone GCP2-02 specifically detects GCP2 in T98G glioblastoma cells. It targets an epitope within 12 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ

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MABT1326100

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Antigen:
BAIAP2
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
__
Immunogen:
His-tagged full-length human recombinant Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2)
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Mouse, Human
Form:
Purified
Applications:
Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
CA-A10-5
Dilution:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
__

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MABT132625

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Antigen:
BAIAP2
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
__
Immunogen:
His-tagged full-length human recombinant Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2)
Quantity:
25 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Mouse, Human
Form:
Purified
Applications:
Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
CA-A10-5
Dilution:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
__

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MABT1330100

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Antigen:
ADAM 12
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
ADAM12;MLTN;UNQ346/PRO545
Immunogen:
A full-length recombinant human ADAM12 secreted expressed in HEK293 cells.
Quantity:
100 μg
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_001275903
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Inhibition Assays, Western Blot
Clone:
8F8
Dilution:
Immunoprecipitation Analysis: A representative lot immunoprecipitated ADAM 12 in Immunoprecipitation applications (Kveiborg, M., et. al. (2005). Cancer Res. 65(11):4754-61).Inhibition Analysis: A representative inhibited ADAM 12 induced gelatin degradation. (Albrechtsen, R., et. al. (2013). J Cell Sci. 126(Pt 20):4707-20). Flow Cytometry Analysis: 1μg from a representative lot detected ADAM 12 in one million ADAM 12-DeltaCyt MCF-7 cells.Immunocytochemistry Analysis: A representative lot detected ADAM 12 in Immunocytochemistry applications (Sundberg, C., et. al. (2004). J Biol Chem. 279(49):51601-11).Western Blotting Analysis: A representative lot detected ADAM 12 in Western Blotting applications (Kveiborg, M., et. al. (2005). Cancer Res. 65(11):4754-61).
Gene Alias:
Disintegrin and metalloproteinase domain-containing protein 12;Meltrin-alpha
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 8F8 detects ADAM 12-DeltaCyt secreted form in human cells. It targets an epitope with in the prodomain region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ