MABT133325

pan-Actin, Mouse anti-Mouse, Rat, Drosophila, Hamster, Human, Monkey, Yeast, Clone: 2A3, Millipore Sigma™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MABT133325-Each-of-1 In Stock ₹ 16,456.61

MABT133325 - Each of 1

₹ 16,456.61

In Stock

Quantity

1

Base Price: ₹ 16,456.61

GST (18%): ₹ 2,962.19

Total Price: ₹ 19,418.80

Antigen

pan-Actin

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols

ACTA1;ACTA2;ACTB;ACTC1;ACTG1;ACTG2

Immunogen

KLH-conjugated linear peptide corresponding to a fragment from the C-terminal region of human Actin.

Quantity

25 μL

Research Discipline

Cell Structure

Gene ID (Entrez)

NP_001092

Target Species

Mouse, Rat, Drosophila, Hamster, Human, Monkey, Yeast

Form

Purified

Applications

Western Blot

Clone

2A3

Dilution

Western Blotting Analysis: A 1:50 dilution from a representative lot detected Actins in various species samples (e.g. Human, rat, mouse, monkey, Hamster, Drosophila, Yeast) (Courtesy of Martina Mitterhuber, M.sc and Egon Ogris, M.D., Medical University of Vienna, Austria).

Gene Alias

Skeletal muscle alpha-actin;Smooth muscle alpha-actin;Cytoplasmic beta-actin;Cardiac muscle alpha-actin;Cytoplasmic gamma-actin;Smooth muscle gamma-actin

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 2A3 detects all forms of actin in multiple species. It targets an epitope with in the C-terminal region.

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Anti-pan-Actin, clone 2A3, Cat
  • No
  • MABT1333, is a mouse monoclonal antibody that detects all forms of actin and has been tested for use in Western Blotting
  • Actin is a multi-functional cytoskeletal protein that serves as the basic building block of cytoskeletal microfilaments
  • Six different actin types have been reported
  • Skeletal muscle alpha-actin (UniProt: P68133) is encoded by the ACTA1 gene, smooth muscle alpha-actin (UniProt: P62736) by the ACTA2 gene, cytoplasmic beta-actin (UniProt: P60709) by the ACTB gene, cardiac muscle alpha-actin (UniProt: P68032) by the ACTC1 gene, cytoplasmic gamma-actin (UniProt: P63261) by the ACTG1 gene, and smooth muscle gamma-actin (UniProt: P63267) by the ACTG2 (also known as ACTA3) gene
  • Although actins show about 90% overall sequence homology, isoforms do show spatial, temporal, and tissue-specific expression patterns and only 50-60% homology is found in their 18 N-terminal residues
  • Cytoplasmic beta and gamma actins are thought to be present in all cells, while the other four actin isoforms are typically found in specific adult muscle tissue types
  • Actins exist in a variety of structural states, depending on the specific ionic conditions or the interaction with ligand proteins
  • The oligomeric and polymeric forms that actin molecules assume are dependent on the distinct conformations they adopt
  • This pan-actin antibody detects all isoforms actin.

Compare Similar Items

Show Difference

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Fischer Scientific

MABT133325

--


Antigen:
pan-Actin

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
ACTA1;ACTA2;ACTB;ACTC1;ACTG1;ACTG2

Immunogen:
KLH-conjugated linear peptide corresponding to a fragment from the C-terminal region of human Actin.

Quantity:
25 μL

Research Discipline:
Cell Structure

Gene ID (Entrez):
NP_001092

Target Species:
Mouse, Rat, Drosophila, Hamster, Human, Monkey, Yeast

Form:
Purified

Applications:
Western Blot

Clone:
2A3

Dilution:
Western Blotting Analysis: A 1:50 dilution from a representative lot detected Actins in various species samples (e.g. Human, rat, mouse, monkey, Hamster, Drosophila, Yeast) (Courtesy of Martina Mitterhuber, M.sc and Egon Ogris, M.D., Medical University of Vienna, Austria).

Gene Alias:
Skeletal muscle alpha-actin;Smooth muscle alpha-actin;Cytoplasmic beta-actin;Cardiac muscle alpha-actin;Cytoplasmic gamma-actin;Smooth muscle gamma-actin

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 2A3 detects all forms of actin in multiple species. It targets an epitope with in the C-terminal region.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

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Fischer Scientific

MABT1334100

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Antigen:
Tropomyosin-4

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
__

Immunogen:
KLH-conjugated linear peptide corresponding to 19 amino acids from the N-terminal region of rat Tropomysin-4 corresponding to exon 1b in Tpm4 gene.

Quantity:
100 μL

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
2D2A12

Dilution:
__

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
__

Img

Fischer Scientific

MABT133425

--


Antigen:
Tropomyosin-4

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
__

Immunogen:
KLH-conjugated linear peptide corresponding to 19 amino acids from the N-terminal region of rat Tropomysin-4 corresponding to exon 1b in Tpm4 gene.

Quantity:
25 μL

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
2D2A12

Dilution:
__

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
__

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MABT13351MI

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Antigen:
Tropomyosin 3

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
Tpm3, Tpm-5, Tpm5

Immunogen:
Diphtheria Toxoid Carrier Protein-conjugated linear peptide corresponding to 27 amino acids from the C-terminal region of rat Tropomyosin alpha-3 chain, isoform 1.

Quantity:
100 μg

Research Discipline:
Cell Structure

Gene ID (Entrez):
__

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Immunofluorescence, Western Blot

Clone:
2G10.2

Dilution:
__

Gene Alias:
Gamma-tropomyosin;Tropomyosin-3;Tropomyosin-5;TPM3;Tm3

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
Clone 2G10.2 is a mouse monoclonal antibody that specifically detects Tropomyosin alpha-3 chain. It targets an epitope within 27 amino acids from the C-terminal region.

Content And Storage:
Stable for 1 year at 2 to 8°C from date of receipt.

Isotype:
IgG2b κ