MABT83125UG
Lamin B Receptor (LBR), Mouse anti-Human, Mouse, Clone: BB2SS3F3, Millipore Sigma™
Manufacturer: MilliporeSigma
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT83125UG-Each-of-1 | In Stock | ₹ 17,067.51 |
MABT83125UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,067.51
GST (18%): ₹ 3,072.152
Total Price: ₹ 20,139.662
Antigen
Lamin B Receptor (LBR)
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
LBR
Immunogen
GST-tagged recombinant fragment corresponding to the first 211 amino acids from human Lamin B receptor.
Quantity
25 μg
Research Discipline
Cell Structure
Test Specificity
Clone BB2SS3F3 detects Lamin B receptor in human cells. It targets an epitope within the first 211 amino acids.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Isotype
IgG1 κ
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Clone
BB2SS3F3
Dilution
Immunofluorescence Analysis: A representative lot detected Lamin B Receptor (LBR) in C57BL/6 mouse small intestine (Courtesy of Dr. Brian Burke, Institute of Medical Biology, A*STAR, Singapore).Western Blotting Analysis: A representative lot detected Lamin B Receptor (LBR) in HeLa cell lysate, mouse C2C12 cell lysate, and in adult mouse fibroblasts (MAFs) either LBR+/+ or LBR -/- (Courtesy of Dr. Brian Burke, Institute of Medical Biology, A*STAR, Singapore).Immunocytochemistry Analysis: A 1:50 dilution from a representative lot detected Lamin B Receptor (LBR) in HeLa cells.Immunocytochemistry Analysis: A representative lot detected Lamin B Receptor (LBR) in HeLa and NIE-115 cells, as well as in mouse adult fibroblasts (MAF LBR+/+ vs MAF LBR-/-) (Courtesy of Dr. Brian Burke, Institute of Medical Biology, A*STAR, Singapore).
Gene Alias
LMN2R;Integral nuclear envelope inner membrane protein;LBR
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Purified
Description
- Anti-Lamin B Receptor (LBR), clone BB2SS3F3, Cat
- No
- MABT831, is a mouse monoclonal antibody that detects Lamin B receptor and has been tested for use in Immunocytochemistry, Immunofluorescence, and Western Blotting
- Lamin-B receptor (UniProt: Q14739; also known as Integral nuclear envelope inner membrane protein, LMN2R) is encoded by the LBR gene (Gene ID: 3930) in human
- Lamin-B receptor is a multi-pass membrane protein that anchors the lamina and the heterochromatin to the inner nuclear membrane
- It is an integral membrane protein of the interphase nuclear envelope (NE)
- It contains a Tudor damain that lies within the first 62 amino acids
- Its N-terminal end resides in the nucleoplasm, binding to lamin B and heterochromatin and the C-terminal end resides within the inner nuclear membrane, retreating with the endoplasmic reticulum (ER) away from condensing chromosomes during mitotic NE breakdown
- During mitosis, Lamin-B receptor is retained within the retreating ER and kept out of the way of the mitotic apparatus
- Lamin- B receptor is suggested to perform three vital functions in the cell: (a) contributes to post-mitotic nuclear reformation; (b) contributes to interphase NE growth; (c) contributes to compartmentalization of heterochromatin within the interphase nucleus
- Lamin-B receptor is phosphorylated by Cdk1 in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin
- It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures
- Mutations in LBR gene are known to cause Pelger-Huet anomaly that is characterized by skeletal anomalies, developmental delay, and seizures
- Some mutations cause Greenberg dysplasia that can lead to in utero lethality
- (Ref.: Olins, AL., et al
- (2010)
- Nucleus 1(1); 53-70).
Compare Similar Items
Show Difference
Antigen: Lamin B Receptor (LBR)
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: LBR
Immunogen: GST-tagged recombinant fragment corresponding to the first 211 amino acids from human Lamin B receptor.
Quantity: 25 μg
Research Discipline: Cell Structure
Test Specificity: Clone BB2SS3F3 detects Lamin B receptor in human cells. It targets an epitope within the first 211 amino acids.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: BB2SS3F3
Dilution: Immunofluorescence Analysis: A representative lot detected Lamin B Receptor (LBR) in C57BL/6 mouse small intestine (Courtesy of Dr. Brian Burke, Institute of Medical Biology, A*STAR, Singapore).Western Blotting Analysis: A representative lot detected Lamin B Receptor (LBR) in HeLa cell lysate, mouse C2C12 cell lysate, and in adult mouse fibroblasts (MAFs) either LBR+/+ or LBR -/- (Courtesy of Dr. Brian Burke, Institute of Medical Biology, A*STAR, Singapore).Immunocytochemistry Analysis: A 1:50 dilution from a representative lot detected Lamin B Receptor (LBR) in HeLa cells.Immunocytochemistry Analysis: A representative lot detected Lamin B Receptor (LBR) in HeLa and NIE-115 cells, as well as in mouse adult fibroblasts (MAF LBR+/+ vs MAF LBR-/-) (Courtesy of Dr. Brian Burke, Institute of Medical Biology, A*STAR, Singapore).
Gene Alias: LMN2R;Integral nuclear envelope inner membrane protein;LBR
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Antigen:
Lamin B Receptor (LBR)
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
LBR
Immunogen:
GST-tagged recombinant fragment corresponding to the first 211 amino acids from human Lamin B receptor.
Quantity:
25 μg
Research Discipline:
Cell Structure
Test Specificity:
Clone BB2SS3F3 detects Lamin B receptor in human cells. It targets an epitope within the first 211 amino acids.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
BB2SS3F3
Dilution:
Immunofluorescence Analysis: A representative lot detected Lamin B Receptor (LBR) in C57BL/6 mouse small intestine (Courtesy of Dr. Brian Burke, Institute of Medical Biology, A*STAR, Singapore).Western Blotting Analysis: A representative lot detected Lamin B Receptor (LBR) in HeLa cell lysate, mouse C2C12 cell lysate, and in adult mouse fibroblasts (MAFs) either LBR+/+ or LBR -/- (Courtesy of Dr. Brian Burke, Institute of Medical Biology, A*STAR, Singapore).Immunocytochemistry Analysis: A 1:50 dilution from a representative lot detected Lamin B Receptor (LBR) in HeLa cells.Immunocytochemistry Analysis: A representative lot detected Lamin B Receptor (LBR) in HeLa and NIE-115 cells, as well as in mouse adult fibroblasts (MAF LBR+/+ vs MAF LBR-/-) (Courtesy of Dr. Brian Burke, Institute of Medical Biology, A*STAR, Singapore).
Gene Alias:
LMN2R;Integral nuclear envelope inner membrane protein;LBR
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Antigen: Galectin-9
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: LGALS9
Immunogen: GST-tagged recombinant protein corresponding to human Galectin-9.
Quantity: 100 μg
Research Discipline: Cell Structure
Test Specificity: Clone 1G3 reacts with all three (L, M, and S) galectin-9 isoforms, but not galectin 1, 2, 3, 4, 7, 8, or 10.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 1G3
Dilution: __
Gene Alias: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Galectin-9
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
LGALS9
Immunogen:
GST-tagged recombinant protein corresponding to human Galectin-9.
Quantity:
100 μg
Research Discipline:
Cell Structure
Test Specificity:
Clone 1G3 reacts with all three (L, M, and S) galectin-9 isoforms, but not galectin 1, 2, 3, 4, 7, 8, or 10.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
1G3
Dilution:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: LBPA
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: __
Immunogen: Endosomal membranes from baby hamster kidney fibroblasts (BHK) corresponding to Hamster LBPA.
Quantity: 100 μg
Research Discipline: Cell Structure
Test Specificity: Clone 6C4 specifically detects LBPA, but not PC, PE, SM, PS, CL, PI, Sul, Chol, Cer, or CE purified from baby hamster kidney (BHK) cell lipid extract (Kobayahsi, T., et al. (1998). Nature. 392(6672):193-197).
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Dot Blot, Immunoassay, ELISA, Immunocytochemistry
Clone: 6C4
Dilution: __
Gene Alias: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: All species
Form: Purified
Antigen:
LBPA
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
__
Immunogen:
Endosomal membranes from baby hamster kidney fibroblasts (BHK) corresponding to Hamster LBPA.
Quantity:
100 μg
Research Discipline:
Cell Structure
Test Specificity:
Clone 6C4 specifically detects LBPA, but not PC, PE, SM, PS, CL, PI, Sul, Chol, Cer, or CE purified from baby hamster kidney (BHK) cell lipid extract (Kobayahsi, T., et al. (1998). Nature. 392(6672):193-197).
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Dot Blot, Immunoassay, ELISA, Immunocytochemistry
Clone:
6C4
Dilution:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
All species
Form:
Purified
Antigen: Myosin 7 (MYH7)
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: Myh7
Immunogen: Purified myosin from bovine atrium.
Quantity: 25 μg
Research Discipline: Cell Structure
Test Specificity: Clone BA-D5 detects Myosin-7 in multiple mammalian species. It detects both alpha- and beta-slow myosin heavy chain.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Clone: BA-D5
Dilution: __
Gene Alias: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Human
Form: Purified
Antigen:
Myosin 7 (MYH7)
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
Myh7
Immunogen:
Purified myosin from bovine atrium.
Quantity:
25 μg
Research Discipline:
Cell Structure
Test Specificity:
Clone BA-D5 detects Myosin-7 in multiple mammalian species. It detects both alpha- and beta-slow myosin heavy chain.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Immunofluorescence, Immunohistochemistry, Western Blot
Clone:
BA-D5
Dilution:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Human
Form:
Purified