MABT837MI
MilliporeSigma™ anti-LBPA Clone: 6C4,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT837MI-Each-of-1 | In Stock | ₹ 45,381.02 |
MABT837MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,381.02
GST (18%): ₹ 8,168.584
Total Price: ₹ 53,549.604
Antigen
LBPA
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
All species
Form
Purified
Applications
Dot Blot, Immunoassay, ELISA, Immunocytochemistry
Clone
6C4
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Immunogen
Endosomal membranes from baby hamster kidney fibroblasts (BHK) corresponding to Hamster LBPA.
Quantity
100 μg
Research Discipline
Cell Structure
Test Specificity
Clone 6C4 specifically detects LBPA, but not PC, PE, SM, PS, CL, PI, Sul, Chol, Cer, or CE purified from baby hamster kidney (BHK) cell lipid extract (Kobayahsi, T., et al. (1998). Nature. 392(6672):193-197).
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Related Products
Description
- Specifically detects LBPA Clone: 6C4 in All samples, and it is validated for Dot Blot, Electron Microscopy, ELISA, Immunocytochemistry Lyso bis-phosphatidic acid (LBPA, Lysobisphosphatidic acid, L(bis)PA) is a lipid that is exclusively located in late endosomes and is used as a late endosome marker
- One of the characteristic features of late endosomes is a complex system of internal membranes within the lumen that contains large amounts of the unique, poorly degradable LBPA, and thus forms a specialized membrane domain within endosomes
- Late endosomes function not only as a major protein-sorting compartment, but also an obligatory station for LDL and other endocytosed ligands destined for degradation
- Research shows that the LBPA-rich membranes within late endosomes regulate cholesterol transport, presumably by acting as a collection and distribution device
- The genetic disease Niemann-Pick type C (NPC) is characterized by both lysosomal and endosomal storage disorders
- In skin fibroblasts from NPC patients, cholesterol accumulation is seen within vesicles containing late endosome markers LBPA and Rab7.
Compare Similar Items
Show Difference
Antigen: LBPA
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: All species
Form: Purified
Applications: Dot Blot, Immunoassay, ELISA, Immunocytochemistry
Clone: 6C4
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Immunogen: Endosomal membranes from baby hamster kidney fibroblasts (BHK) corresponding to Hamster LBPA.
Quantity: 100 μg
Research Discipline: Cell Structure
Test Specificity: Clone 6C4 specifically detects LBPA, but not PC, PE, SM, PS, CL, PI, Sul, Chol, Cer, or CE purified from baby hamster kidney (BHK) cell lipid extract (Kobayahsi, T., et al. (1998). Nature. 392(6672):193-197).
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Antigen:
LBPA
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
All species
Form:
Purified
Applications:
Dot Blot, Immunoassay, ELISA, Immunocytochemistry
Clone:
6C4
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Immunogen:
Endosomal membranes from baby hamster kidney fibroblasts (BHK) corresponding to Hamster LBPA.
Quantity:
100 μg
Research Discipline:
Cell Structure
Test Specificity:
Clone 6C4 specifically detects LBPA, but not PC, PE, SM, PS, CL, PI, Sul, Chol, Cer, or CE purified from baby hamster kidney (BHK) cell lipid extract (Kobayahsi, T., et al. (1998). Nature. 392(6672):193-197).
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Antigen: Myosin 7 (MYH7)
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Human
Form: Purified
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Clone: BA-D5
Formulation: __
Immunogen: Purified myosin from bovine atrium.
Quantity: 25 μg
Research Discipline: Cell Structure
Test Specificity: Clone BA-D5 detects Myosin-7 in multiple mammalian species. It detects both alpha- and beta-slow myosin heavy chain.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
Myosin 7 (MYH7)
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Human
Form:
Purified
Applications:
Immunofluorescence, Immunohistochemistry, Western Blot
Clone:
BA-D5
Formulation:
__
Immunogen:
Purified myosin from bovine atrium.
Quantity:
25 μg
Research Discipline:
Cell Structure
Test Specificity:
Clone BA-D5 detects Myosin-7 in multiple mammalian species. It detects both alpha- and beta-slow myosin heavy chain.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: Aggrecan
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Bovine, Human
Form: Purified
Applications: Immunohistochemistry, Western Blot
Clone: 6B4
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Immunogen: Ovalbumin-conjugated linear peptide corresponding to human Aggrecan.
Quantity: 100 μg
Research Discipline: __
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Antigen:
Aggrecan
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Bovine, Human
Form:
Purified
Applications:
Immunohistochemistry, Western Blot
Clone:
6B4
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Immunogen:
Ovalbumin-conjugated linear peptide corresponding to human Aggrecan.
Quantity:
100 μg
Research Discipline:
__
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Antigen: Podoplanin
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Monkey, Human
Form: Purified
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone: LpMab-12
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Immunogen: LN229 glioma cells expressing human Podoplanin.
Quantity: 25 μg
Research Discipline: Cell Structure
Test Specificity: Clone LpMab-12 detects Podoplanin in human and monkey cells. It targets an epitope within the N-terminal half. It specifically detects Sialylated O-Glycan on Thr52 of platelet aggregation-stimulating domain of human podoplanin. The minimal epitope of LpMab-12 is identified as Asp49-Pro53.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Podoplanin
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Monkey, Human
Form:
Purified
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone:
LpMab-12
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Immunogen:
LN229 glioma cells expressing human Podoplanin.
Quantity:
25 μg
Research Discipline:
Cell Structure
Test Specificity:
Clone LpMab-12 detects Podoplanin in human and monkey cells. It targets an epitope within the N-terminal half. It specifically detects Sialylated O-Glycan on Thr52 of platelet aggregation-stimulating domain of human podoplanin. The minimal epitope of LpMab-12 is identified as Asp49-Pro53.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ