MABE1120MI
MilliporeSigma™ anti- HSPA8/Hsc70 Clone: N69,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE1120MI-Each-of-1 | In Stock | ₹ 40,197.80 |
MABE1120MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,197.80
GST (18%): ₹ 7,235.604
Total Price: ₹ 47,433.404
Antigen
HSPA8/Hsc70
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P19120
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone N69 reacts with the constitutively expressed HSPA8/Hsc70 (HSC73), but not the heat schock-inducible HSP72 (Demidov, O.N., et al. (1999). Eur. J. Cardiothorac. Surg. 16(4):444-449).
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
N69
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
HSPA8, HSC70
Immunogen
Co-purified Hsc73 and Hsp72 proteins from bovine skeletal muscle.
Quantity
100 μg
Research Discipline
Epigenetics, Nuclear Function
Gene ID (Entrez)
NP_776770
Target Species
Bovine, Human, Mouse, Rat
Form
Purified
Related Products
Description
- Specifically detects HSPA8/Hsc70 Clone: N69 in Bovine, Human, Mouse, Rat samples, and it is validated for Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blotting Heat shock cognate 71kDa protein (UniProt P19120; also known as Heat shock 70kDa protein 8, HSC70, HSC71, HSC73) is encoded by the HSPA8 (also known as HSC70, HSC73) gene (Gene ID 281831) in bovine species
- The mammalian HSP70 family consists of the mitochondrial HSP75, the endoplasmic HSP78, the cytoplasmic HSC70 (a.k.a
- HSC73 and HSP73) and its inducible counterpart HSP72 (a.k.a
- HSP70)
- The latter two have similar structures and properties, and both of them bind misfolded, newly synthesized polypeptides in an ATP-dependent manner, reflecting their chaperonic activity
- All cells constitutively express HSC70
- On the other hand, the expression of HSP72 in normal cells is mainly stress inducible, although constitutively high HSP72 expressions are observed in malignant human tumors of various origins
- The induced HSP72 expression enables stressed cells to better cope with the elevation of unfolded/denatured proteins and prevent apoptosis under various stress conditions.
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Antigen: HSPA8/Hsc70
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P19120
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone N69 reacts with the constitutively expressed HSPA8/Hsc70 (HSC73), but not the heat schock-inducible HSP72 (Demidov, O.N., et al. (1999). Eur. J. Cardiothorac. Surg. 16(4):444-449).
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: N69
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: HSPA8, HSC70
Immunogen: Co-purified Hsc73 and Hsp72 proteins from bovine skeletal muscle.
Quantity: 100 μg
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NP_776770
Target Species: Bovine, Human, Mouse, Rat
Form: Purified
Antigen:
HSPA8/Hsc70
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P19120
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone N69 reacts with the constitutively expressed HSPA8/Hsc70 (HSC73), but not the heat schock-inducible HSP72 (Demidov, O.N., et al. (1999). Eur. J. Cardiothorac. Surg. 16(4):444-449).
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
N69
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
HSPA8, HSC70
Immunogen:
Co-purified Hsc73 and Hsp72 proteins from bovine skeletal muscle.
Quantity:
100 μg
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NP_776770
Target Species:
Bovine, Human, Mouse, Rat
Form:
Purified
Antigen: XPA
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P23025
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: -20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype: IgG1 κ
Applications: Immunocytochemistry, Western Blot
Clone: 1XPA-1E11
Formulation: Mouse monoclonal IgG1κ ascites with 0.05% sodium azide.
Gene Symbols: XPA, XPAC
Immunogen: Linear peptide corresponding to human XPA sequence near C-terminus.
Quantity: 100 μL
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NP_000371
Target Species: Human
Form: Ascites
Antigen:
XPA
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P23025
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Western Blot
Clone:
1XPA-1E11
Formulation:
Mouse monoclonal IgG1κ ascites with 0.05% sodium azide.
Gene Symbols:
XPA, XPAC
Immunogen:
Linear peptide corresponding to human XPA sequence near C-terminus.
Quantity:
100 μL
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NP_000371
Target Species:
Human
Form:
Ascites
Antigen: BORIS/CTCFL
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q8NI51
Host Species: Human
Purification Method: Purified by ion-exchange chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with spliced isoforms 1, 2, 3, 4, 7, 8, 9, but not isoforms 6 and 11. Reactivity to isoforms 5 and 10 has not been determined.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgM κ
Applications: ChIP Assay, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 4A7
Formulation: Purified mouse monoclonal IgMκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CTCFL, BORIS, CT27, CTCF-T, dJ579F20.2, HMGB1L1
Immunogen: His-tagged recombinant human BORIS/CTCFL N-terminal fragment.
Quantity: 100 μg
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NP_001255969.1
Target Species: Human, Mouse
Form: Purified
Antigen:
BORIS/CTCFL
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q8NI51
Host Species:
Human
Purification Method:
Purified by ion-exchange chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with spliced isoforms 1, 2, 3, 4, 7, 8, 9, but not isoforms 6 and 11. Reactivity to isoforms 5 and 10 has not been determined.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgM κ
Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
4A7
Formulation:
Purified mouse monoclonal IgMκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CTCFL, BORIS, CT27, CTCF-T, dJ579F20.2, HMGB1L1
Immunogen:
His-tagged recombinant human BORIS/CTCFL N-terminal fragment.
Quantity:
100 μg
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NP_001255969.1
Target Species:
Human, Mouse
Form:
Purified
Antigen: __
Classification: __
Conjugate: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Applications: __
Clone: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Applications:
__
Clone:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__