MABF850MI
MilliporeSigma™ anti-IDO-1 Clone: 4B7,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF850MI-Each-of-1 | In Stock | ₹ 34,965.81 |
MABF850MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,965.81
GST (18%): ₹ 6,293.846
Total Price: ₹ 41,259.656
Antigen
IDO-1
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P28776
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Target specificity of clone 4B7 has been confirmed by both immunohistochemistry and Western blotting using tissue samples from wild-type and Ido1-knockout mice (Thomas, S., et al. (2014). J. Cell. Biochem. 115(2):391-396).
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
4B7
Formulation
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
Ido1, Ido, Indo
Immunogen
KLH-conjugated linear peptide corresponding to the N-terminal region of mouse IDO-1.
Quantity
100 μg
Research Discipline
Inflammation, Immunology
Gene ID (Entrez)
NP_032350
Target Species
Mouse, Rat
Form
Purified
Related Products
Description
- Specifically detects IDO-1 Clone: 4B7 in Mouse, Rat samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting Indoleamine 2,3-dioxygenase 1 (EC 1.13.11.52; UniProt P28776; also known as IDO-1, indole 2,3-dioxygenase, Indoleamine-pyrrole 2,3-dioxygenase) is encoded by the Ido1 (also known as Ido, Indo) gene (Gene ID 15930) in murine species
- Indoleamine 2,3-dioxygenase-1 (IDO1) is a heme containing enzyme that catalyzes the rate-limiting step in tryptophan catabolism to N-formyl-kynurenine
- The reduction in local tryptophan and the upregulated immunomodulatory tryptophan metabolites form the basis of IDO-dependent regulation of inflammation and immunity
- IDO is reported to support carcinogenesis by modulating tissue microenvironment inflammatory responses
- IDO is also reported to mediate immune escape in cancer by suppressing the function of T effector cells and promote the differentiation of T regulatory cells.
Compare Similar Items
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Antigen: IDO-1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P28776
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Target specificity of clone 4B7 has been confirmed by both immunohistochemistry and Western blotting using tissue samples from wild-type and Ido1-knockout mice (Thomas, S., et al. (2014). J. Cell. Biochem. 115(2):391-396).
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 4B7
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Ido1, Ido, Indo
Immunogen: KLH-conjugated linear peptide corresponding to the N-terminal region of mouse IDO-1.
Quantity: 100 μg
Research Discipline: Inflammation, Immunology
Gene ID (Entrez): NP_032350
Target Species: Mouse, Rat
Form: Purified
Antigen:
IDO-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P28776
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Target specificity of clone 4B7 has been confirmed by both immunohistochemistry and Western blotting using tissue samples from wild-type and Ido1-knockout mice (Thomas, S., et al. (2014). J. Cell. Biochem. 115(2):391-396).
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
4B7
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Ido1, Ido, Indo
Immunogen:
KLH-conjugated linear peptide corresponding to the N-terminal region of mouse IDO-1.
Quantity:
100 μg
Research Discipline:
Inflammation, Immunology
Gene ID (Entrez):
NP_032350
Target Species:
Mouse, Rat
Form:
Purified
Antigen: S100A9
Classification: Monoclonal
Conjugate: __
Gene Accession No.: P06702
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG1 κ
Applications: ELISA, Western Blot
Clone: 6B4
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing PBS without preservatives.
Gene Symbols: S100A9; CAGB; CFAG; MRP14
Immunogen: Recombinant protein corresponding to human S100A9.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_002956
Target Species: Human
Form: Purified
Antigen:
S100A9
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
P06702
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG1 κ
Applications:
ELISA, Western Blot
Clone:
6B4
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing PBS without preservatives.
Gene Symbols:
S100A9; CAGB; CFAG; MRP14
Immunogen:
Recombinant protein corresponding to human S100A9.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_002956
Target Species:
Human
Form:
Purified
Antigen: CAP-18/CAMP
Classification: Monoclonal
Conjugate: __
Gene Accession No.: P49913
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: H7
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CAMP; CAP18; FALL39; HSD26; LL37
Immunogen: Human cytochrome b preparation containing co-purified hCAP-18.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_034051
Target Species: Human
Form: Purified
Antigen:
CAP-18/CAMP
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
P49913
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
H7
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CAMP; CAP18; FALL39; HSD26; LL37
Immunogen:
Human cytochrome b preparation containing co-purified hCAP-18.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_034051
Target Species:
Human
Form:
Purified
Antigen: __
Classification: __
Conjugate: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Applications: __
Clone: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Applications:
__
Clone:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__