MABS1152MI
MilliporeSigma™ anti-ROR2 Clone: Nt2535-2835,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1152MI-Each-of-1 | In Stock | ₹ 31,588.75 |
MABS1152MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,588.75
GST (18%): ₹ 5,685.975
Total Price: ₹ 37,274.725
Antigen
ROR2
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
Q9Z138
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Purified
Applications
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
Nt2535-2835
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
Ror2
Immunogen
Recombinant protein corresponding to the second Ser/Thr-rich domain of mouse mRor2.
Quantity
100 μg
Research Discipline
Signaling
Test Specificity
Clone Nt 2535-2835 is specific to the mouse and human ROR2, but does not detect mouse ROR1. Clone Nt 2535-2835 exclusively detects ROR2 protein in paraffin-embedded tissues (Mikels, A., et al. (2009). J. Biol. Chem. 284(44):30167-30176).
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Related Products
Description
- Specifically detects ROR2 Clone: Nt2535-2835 in Human, Mouse samples, and it is validated for ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blotting Tyrosine-protein kinase transmembrane receptor ROR2 (EC 2.7.10.1; UniProt Q9Z138; also known as mRor2, Ntrkr2, Neurotrophic tyrosine kinase receptor-related 2) is encoded by the Ror2 gene (Gene ID 26564) in murine species
- Ror2 is a receptor tyrosine kinase that binds Wnt5a and negatively regulates canonical Wnt signaling
- Although in C
- elegans and Xenopus Ror2 is reported to modulate Wnt signaling nonautonomously by preventing Wnt from stimulating adjacent cells, studies conducted in mammalian cells suggest that Ror2 cytoplasmic domain is crucial for its function and Ror2 inhibits Wnt signaling in a cell-autonomous manner
- Ror2 and the closely related Ror1 play essential roles during development
- Human ROR2 gene mutations have been associated with dominant Brachydactyly B and recessive Robinow syndrome
- Ror2-null mice exhibit skeletal abnormalities similar to the human syndromes
- In addition, these mice display heart and lung defects and die perinatally
- Ror2 is initially translated with an N-terminal signal sequence (a.a
- 1-33), the removal of which yields the mature receptor with an extracellular region (a.a
- 34-403), a transmembrane segment (a.a
- 404-424), followed by the cytoplasmic region (a.a
- 425-944) that contains the kinase domain (a.a
- 473-746), a Pro-rich domain (a.a
- 784-857) sandwiched between two Ser/Thr-rich domains (a.a
- 753-782 and a.a
- 859-882).
Compare Similar Items
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Antigen: ROR2
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q9Z138
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: Nt2535-2835
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Ror2
Immunogen: Recombinant protein corresponding to the second Ser/Thr-rich domain of mouse mRor2.
Quantity: 100 μg
Research Discipline: Signaling
Test Specificity: Clone Nt 2535-2835 is specific to the mouse and human ROR2, but does not detect mouse ROR1. Clone Nt 2535-2835 exclusively detects ROR2 protein in paraffin-embedded tissues (Mikels, A., et al. (2009). J. Biol. Chem. 284(44):30167-30176).
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Antigen:
ROR2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q9Z138
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
Nt2535-2835
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Ror2
Immunogen:
Recombinant protein corresponding to the second Ser/Thr-rich domain of mouse mRor2.
Quantity:
100 μg
Research Discipline:
Signaling
Test Specificity:
Clone Nt 2535-2835 is specific to the mouse and human ROR2, but does not detect mouse ROR1. Clone Nt 2535-2835 exclusively detects ROR2 protein in paraffin-embedded tissues (Mikels, A., et al. (2009). J. Biol. Chem. 284(44):30167-30176).
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Antigen: Derlin-1
Classification: Monoclonal
Conjugate: __
Gene Accession No.: Q9BUN8
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Applications: Immunocytochemistry, Western Blot
Clone: 8G11.2
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: DERL1; DER1; UNQ243/PRO276
Immunogen: GST-tagged recombinant human derlin-1 C-terminal cytoplasmic fragment.
Quantity: 100 μg
Research Discipline: Signaling
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
Derlin-1
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
Q9BUN8
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Applications:
Immunocytochemistry, Western Blot
Clone:
8G11.2
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
DERL1; DER1; UNQ243/PRO276
Immunogen:
GST-tagged recombinant human derlin-1 C-terminal cytoplasmic fragment.
Quantity:
100 μg
Research Discipline:
Signaling
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: Fibrocystin
Classification: Monoclonal
Conjugate: __
Gene Accession No.: P08F94
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Rat
Form: Purified
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone: 18
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: PKHD1; FCYT; TIGM1
Immunogen: Recombinant protein corresponding to human Fibrocystin fragment from the N-terminal half.
Quantity: 100 μg
Research Discipline: Signaling
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Fibrocystin
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
P08F94
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Rat
Form:
Purified
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone:
18
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
PKHD1; FCYT; TIGM1
Immunogen:
Recombinant protein corresponding to human Fibrocystin fragment from the N-terminal half.
Quantity:
100 μg
Research Discipline:
Signaling
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: PYCR1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P32322
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 2D9.1
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant protein corresponding to the C-terminal of human PYCR1.
Quantity: 100 μg
Research Discipline: Signaling
Test Specificity: Expected to react with spliced isoforms 1 and 3, but not isoform 2, reported by UniProt P32322).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
PYCR1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P32322
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
2D9.1
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal of human PYCR1.
Quantity:
100 μg
Research Discipline:
Signaling
Test Specificity:
Expected to react with spliced isoforms 1 and 3, but not isoform 2, reported by UniProt P32322).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ