MABE1124MI
MilliporeSigma™ anti-XPA Clone: 1XPA-1E11,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE1124MI-Each-of-1 | In Stock | ₹ 36,363.00 |
MABE1124MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,363.00
GST (18%): ₹ 6,545.34
Total Price: ₹ 42,908.34
Antigen
XPA
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P23025
Host Species
Mouse
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Ascites
Applications
Immunocytochemistry, Western Blot
Clone
1XPA-1E11
Formulation
Mouse monoclonal IgG1κ ascites with 0.05% sodium azide.
Gene Symbols
XPA, XPAC
Immunogen
Linear peptide corresponding to human XPA sequence near C-terminus.
Quantity
100 μL
Research Discipline
Epigenetics, Nuclear Function
Gene ID (Entrez)
NP_000371
Content And Storage
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype
IgG1 κ
Related Products
Description
- Specifically detects XPA Clone: 1XPA-1E11 in Human samples, and it is validated for Immunocytochemistry, Western Blotting DNA repair protein complementing XP-A cells (UniProt P23025; also known as Excision repair-controlling, Mutant xeroderma pigmentosum complementation group A, Xeroderma pigmentosum group A-complementing protein) is encoded by the XPA (also known as XP1, XPAC) gene (Gene ID 7507) in human
- DNA lesions caused by UV irradiation, drugs, or other environmental factors are eliminated by two nucleotide excision repair (NER) pathways, Global genome repair (GGR) and transcription-coupled repair (TCR)
- In GGR, the removal of lesions requires their recognition by the repair factor XPC/HR23b and the subsequent opening of the DNA duplex by transcription factor II human (TFIIH)
- The resulting single-stranded structure is stabilized by XPA and replication protein A (RPA)
- XPG is recruited through its interaction with TFIIH on the 3' side of the lesion and its positioning on the cut site requires RPA
- The interaction between XPA and XPB (ERCC1) stimulates the recruitment of ERCC1-XPF on the 5' side of the DNA lesion
- The damaged oligonucleotide can then be removed through the double incision by XPG and ERCC1-XPF endonucleases
- In TCR, these factors (except XPC/HR23B) are recruited by the stalled RNA pol II in front of the damage with the help of the CSB and CSA proteins.
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Antigen: XPA
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P23025
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Ascites
Applications: Immunocytochemistry, Western Blot
Clone: 1XPA-1E11
Formulation: Mouse monoclonal IgG1κ ascites with 0.05% sodium azide.
Gene Symbols: XPA, XPAC
Immunogen: Linear peptide corresponding to human XPA sequence near C-terminus.
Quantity: 100 μL
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NP_000371
Content And Storage: -20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype: IgG1 κ
Antigen:
XPA
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P23025
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Ascites
Applications:
Immunocytochemistry, Western Blot
Clone:
1XPA-1E11
Formulation:
Mouse monoclonal IgG1κ ascites with 0.05% sodium azide.
Gene Symbols:
XPA, XPAC
Immunogen:
Linear peptide corresponding to human XPA sequence near C-terminus.
Quantity:
100 μL
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NP_000371
Content And Storage:
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype:
IgG1 κ
Antigen: BORIS/CTCFL
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q8NI51
Host Species: Human
Purification Method: Purified by ion-exchange chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Applications: ChIP Assay, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 4A7
Formulation: Purified mouse monoclonal IgMκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CTCFL, BORIS, CT27, CTCF-T, dJ579F20.2, HMGB1L1
Immunogen: His-tagged recombinant human BORIS/CTCFL N-terminal fragment.
Quantity: 100 μg
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NP_001255969.1
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgM κ
Antigen:
BORIS/CTCFL
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q8NI51
Host Species:
Human
Purification Method:
Purified by ion-exchange chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
4A7
Formulation:
Purified mouse monoclonal IgMκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CTCFL, BORIS, CT27, CTCF-T, dJ579F20.2, HMGB1L1
Immunogen:
His-tagged recombinant human BORIS/CTCFL N-terminal fragment.
Quantity:
100 μg
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NP_001255969.1
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgM κ
Antigen: __
Classification: __
Conjugate: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Form: __
Applications: __
Clone: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
__
Isotype:
__
Antigen: DNA G-quadruplex (G4)
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: All species
Form: Purified
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), ELISA, Flow Cytometry
Clone: 1H6
Formulation: __
Gene Symbols: __
Immunogen: KLH-conjugated G-quadruplex DNA derived from oligonucleotides with telomeric repeats.
Quantity: 100 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): __
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
DNA G-quadruplex (G4)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
All species
Form:
Purified
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), ELISA, Flow Cytometry
Clone:
1H6
Formulation:
__
Gene Symbols:
__
Immunogen:
KLH-conjugated G-quadruplex DNA derived from oligonucleotides with telomeric repeats.
Quantity:
100 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ