MABS1248MI

MilliporeSigma™ anti-PPIase FKBP4 Clone: KN382/EC1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS1248MI-Each-of-1 In Stock ₹ 44,990.87

MABS1248MI - Each of 1

₹ 44,990.87

In Stock

Quantity

1

Base Price: ₹ 44,990.87

GST (18%): ₹ 8,098.357

Total Price: ₹ 53,089.227

Antigen

PPIase FKBP4

Classification

Monoclonal

Conjugate

Unconjugated

Gene Accession No.

P27124

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Rabbit

Form

Purified

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot

Clone

KN382/EC1

Formulation

Purified mouse monoclonal IgG1κ antibody in PBS without preservatives.

Gene Symbols

FKBP4, P59

Immunogen

Nonactivated (8.5S) rabbit uterine progestin receptor.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_001075779

Content And Storage

-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Isotype

IgG1 κ

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Description

  • Specifically detects PPIase FKBP4 Clone: KN382/EC1 in Human, Rabbit samples, and it is validated for Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Radioimmunoassay, Western Blotting Peptidyl-prolyl cis-trans isomerase FKBP4 (EC 5.2.1.8; UniProt P27124; also known as 52kDa FK506-binding protein, 52kDa FKBP, 52kDa immunophilin, FK506-binding protein 4, FKBP-4, FKBP-52, FKBP59, HBI, HSP-binding immunophilin, Immunophilin FKBP52, PPIase FKBP4, p59, Rotamase) is encoded by the FKBP4 (also known as P59) gene (Gene ID 100009148) in rabbit
  • PPIase FKBP4 (FKBP52, FKBP59, p59) is an immunophilin that binds the immunosuppressant drugs FK506 and rapamycin
  • FKBP59 was originally identified in the rabbit as a component of the unliganded, nontransformed steroid hormone receptor oligomeric complexes, where it was found associated with the chaperon protein hsp90 involved in protein folding
  • All the immunophilins are implicated in protein conformation regulations by catalyzing the cis-trans isomerization of proline imidic peptide bonds via their peptidylprolyl isomerase (rotamase) activity
  • FKBP59 is expressed at a higher level in the testis than in other organs
  • A high FKBP59 expression occurs in germ cells that have reached the same developmental stages either during prepubertal development or differentiation along the seminiferous tubules in the adult
  • The developmental stage-specific expression of FKBP59 during male germ cell differentiation suggests a role during the cell division.

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MilliporeSigma™

MABS1248MI

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Antigen:
PPIase FKBP4

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
P27124

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Rabbit

Form:
Purified

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot

Clone:
KN382/EC1

Formulation:
Purified mouse monoclonal IgG1κ antibody in PBS without preservatives.

Gene Symbols:
FKBP4, P59

Immunogen:
Nonactivated (8.5S) rabbit uterine progestin receptor.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001075779

Content And Storage:
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Isotype:
IgG1 κ

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MABS1250MI

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Antigen:
Mineralocorticoid Receptor

Classification:
Monoclonal

Conjugate:
__

Gene Accession No.:
P22199

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Rat

Form:
Purified

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
2D6

Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Nr3c2; Mlr

Immunogen:
Conjugated linear peptide corresponding to the N-terminus of rat Mineralocorticoid Receptor.

Quantity:
200 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_037263

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ

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MABS1251MI

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Antigen:
CYP11B2

Classification:
Monoclonal

Conjugate:
__

Gene Accession No.:
P19099

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
41-17B

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
CYP11B2

Immunogen:
Chicken serum albumin-conjugated linear peptide corresponding to human CYP11B2 near the N-terminus.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_000489

Content And Storage:
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Antigen:
Polycystin-1

Classification:
Monoclonal

Conjugate:
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Gene Accession No.:
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Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
E4 (5F4D2)

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
PKD1

Immunogen:
FLAG-tagged recombinant human polycystin-1 C-type lectin domain.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001009944.2

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ