MABF978MI
MilliporeSigma™ anti-GD3, 9-O-acetyl Clone: UM4D4,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF978MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABF978MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
GD3, 9-O-acetyl
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Purified by ion-exchange chromatography
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
Clone
UM4D4
Formulation
Purified mouse monoclonal IgMκ antibody in PBS without preservatives.
Immunogen
Human rheumatoid synovial T cell line ST-1.
Quantity
100 μL
Research Discipline
Inflammation, Immunology
Test Specificity
Clone UM4D4 detects 9-O-acetylated ganglioside GD3. GD3 is also known as CD60a. 9-O-acetylated GD3 is known as CDw60 or CD60b, while 7-O-acetylated GD3 is known as CD60c.
Content And Storage
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype
IgM κ
Related Products
Description
- Specifically detects GD3, 9-O-acetyl Clone: UM4D4 in Human samples, and it is validated for Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry Gangliosides are sialic acid-containing oligoglycosylceramides
- The German scientist Ernst Klenk used ganglioside in 1942 to refer to lipids isolated from ganglions
- Gangliosides are grouped based on the number of sialic acid residues per molecule, GM gangliosides contain one sialic acid residue, GD gangliosides contain two, GT contain three, GQ contain four sialic acid residues
- Sialyltransferase-catalyzed α2-3 sialylation of the galactose of the trisaccharide Galβ1-4Glcβ1-1'Cer produces GM3, which can be further sialylated to produce GD3 with two sialic acid on the galactose
- A de-N-acetylated form of ganglioside GD3 has been detected in human melanoma tumors
- In addition, O-acetylation or lactonization of the sialic acid residue adds to the potential complexity
- Gangliosides containing O-acetylated sialic acids, such as 9-OAc-GD3, occur in certain tumors and may protect cancer cells from apoptosis
- GD3 is also known as CD60a
- 9-O-acetylated GD3 is known as CDw60 or CD60b, while 7-O-acetylated GD3 is known as CD60c.
Compare Similar Items
Show Difference
Antigen: GD3, 9-O-acetyl
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Purified by ion-exchange chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
Clone: UM4D4
Formulation: Purified mouse monoclonal IgMκ antibody in PBS without preservatives.
Immunogen: Human rheumatoid synovial T cell line ST-1.
Quantity: 100 μL
Research Discipline: Inflammation, Immunology
Test Specificity: Clone UM4D4 detects 9-O-acetylated ganglioside GD3. GD3 is also known as CD60a. 9-O-acetylated GD3 is known as CDw60 or CD60b, while 7-O-acetylated GD3 is known as CD60c.
Content And Storage: -20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype: IgM κ
Antigen:
GD3, 9-O-acetyl
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Purified by ion-exchange chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
Clone:
UM4D4
Formulation:
Purified mouse monoclonal IgMκ antibody in PBS without preservatives.
Immunogen:
Human rheumatoid synovial T cell line ST-1.
Quantity:
100 μL
Research Discipline:
Inflammation, Immunology
Test Specificity:
Clone UM4D4 detects 9-O-acetylated ganglioside GD3. GD3 is also known as CD60a. 9-O-acetylated GD3 is known as CDw60 or CD60b, while 7-O-acetylated GD3 is known as CD60c.
Content And Storage:
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype:
IgM κ
Antigen: Bst2
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Inhibition Assays, Western Blot
Clone: 44E9
Formulation: Purified rat monoclonal IgG2aκ antibody in PBS without preservatives.
Immunogen: Recombinant protein corresponding to the extracellular domain of mouse Bst2.
Quantity: 100 μg
Research Discipline: Inflammation, Immunology
Test Specificity: __
Content And Storage: -20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype: IgG2a κ
Antigen:
Bst2
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Inhibition Assays, Western Blot
Clone:
44E9
Formulation:
Purified rat monoclonal IgG2aκ antibody in PBS without preservatives.
Immunogen:
Recombinant protein corresponding to the extracellular domain of mouse Bst2.
Quantity:
100 μg
Research Discipline:
Inflammation, Immunology
Test Specificity:
__
Content And Storage:
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype:
IgG2a κ
Antigen: CD22
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Applications: Flow Cytometry, Immunoprecipitation
Clone: CY34
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Immunogen: Splenocytes from mouse strain B10.D2
Quantity: 100 μg
Research Discipline: Inflammation, Immunology
Test Specificity: Murine Cd22 gene is also known as Lyb-8. The epitope detected by clone CY34 is not expressed by all strains of mice due to Cd22 polymorphisms. Clone CY34 is known to react with Cd22 expressed on splenocytes from murine strains B10.D2 and BALB/c, C57BL/6, but not DBA/2J. Consequently, the allelic form of Cd22 from DBA/2J is designated as mCD22.1/Lyb-8.1 to distinquish it from the form of Cd22 recognized by clone CY34, originally designated as Lyb-8.2 (PMID 8100843 and 6984010).
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Antigen:
CD22
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Purified
Applications:
Flow Cytometry, Immunoprecipitation
Clone:
CY34
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Immunogen:
Splenocytes from mouse strain B10.D2
Quantity:
100 μg
Research Discipline:
Inflammation, Immunology
Test Specificity:
Murine Cd22 gene is also known as Lyb-8. The epitope detected by clone CY34 is not expressed by all strains of mice due to Cd22 polymorphisms. Clone CY34 is known to react with Cd22 expressed on splenocytes from murine strains B10.D2 and BALB/c, C57BL/6, but not DBA/2J. Consequently, the allelic form of Cd22 from DBA/2J is designated as mCD22.1/Lyb-8.1 to distinquish it from the form of Cd22 recognized by clone CY34, originally designated as Lyb-8.2 (PMID 8100843 and 6984010).
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Antigen: Complement C3b/iC3b
Classification: Monoclonal
Conjugate: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Applications: Flow Cytometry
Clone: 6C9
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing PBS without preservatives.
Immunogen: Human C3 corresponding to the iC3b of human Complement C3b/iC3b.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG1 κ
Antigen:
Complement C3b/iC3b
Classification:
Monoclonal
Conjugate:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Applications:
Flow Cytometry
Clone:
6C9
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing PBS without preservatives.
Immunogen:
Human C3 corresponding to the iC3b of human Complement C3b/iC3b.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG1 κ