MAB5606ZMI
MilliporeSigma™ anti-GD1a Ganglioside Clone: GD1a-1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MAB5606ZMI-Each-of-1 | In Stock | ₹ 50,364.04 |
MAB5606ZMI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,364.04
GST (18%): ₹ 9,065.527
Total Price: ₹ 59,429.567
Antigen
GD1a Ganglioside
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Bovine, Fish, Human, Mouse, Rat
Form
Purified
Applications
ELISA, Immunohistochemistry (Paraffin)
Clone
GD1a-1
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl without preservatives.
Immunogen
KLH-conjugated GD1a ganglioside.
Quantity
100 μg
Research Discipline
Neuroscience
Test Specificity
GD1a ganglioside. The antibody shows approximately 10% reactivity to GalNAc-GD1a and GT1aα. Preferentially binds to motor myelinated fibers in cross-sections of ventral roots and sciatic nerves.
Content And Storage
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype
IgG1 κ
Related Products
Description
- Specifically detects GD1a Ganglioside Clone: GD1a-1 in Bovine, Fish, Human, Mouse, Rat samples, and it is validated for ELISA, Enzyme Immunoassay, Immunohistochemistry (Paraffin) Gangliosides are sialic acid-containing oligoglycosylceramides
- The German scientist Ernst Klenk used the term ganglioside in 1942 to refer to lipids isolated from ganglions
- Gangliosides are grouped based on the number of sialic acid residues per molecule, GM gangliosides contain one sialic acid residue, GD gangliosides contain two, GT contain three, GQ contain four sialic acid residues
- Glycolipids constitute >80% of mammalian brain glycans, with gangliosides being the major glycans in nerve cells
- Among the hundreds of ganglioside structures, GM1a, GD1a, GD1b and GT1b comprise up to 97% of gangliosides in the human brain
- These four gangliosides share the same neutral tetrasaccharide core (Galβ1-3GalNAcβ1-4Galβ1-4Glcβ1-1'Cer), but differ from each other by their sialic acid residue(s)
- GM1a and GD1b contain one or two sialic acids on the internal galactose, respectively, and no sialic acid on the terminal galactose
- The St3gal2 and St3gal3 gene products (ST3Gal-II and ST3Gal-III sialyltransferase, respectively) are largely responsible for ganglioside terminal α2-3 sialylation of GM1a and GD1b to produce GD1a and GT1b in the brain
- Brain GD1a and GT1b in St3gal2-null mice is about half the level in wild-type mice, while GD1a and GT1b level in St3gal2/3-double-null mice is less than 5% of the level in wild-type mice
- St3gal2/3-double-null mice are half the weight of wild-type mice at weaning and display early hindlimb dysreflexia.
Compare Similar Items
Show Difference
Antigen: GD1a Ganglioside
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Bovine, Fish, Human, Mouse, Rat
Form: Purified
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: GD1a-1
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl without preservatives.
Immunogen: KLH-conjugated GD1a ganglioside.
Quantity: 100 μg
Research Discipline: Neuroscience
Test Specificity: GD1a ganglioside. The antibody shows approximately 10% reactivity to GalNAc-GD1a and GT1aα. Preferentially binds to motor myelinated fibers in cross-sections of ventral roots and sciatic nerves.
Content And Storage: -20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype: IgG1 κ
Antigen:
GD1a Ganglioside
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Bovine, Fish, Human, Mouse, Rat
Form:
Purified
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
GD1a-1
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl without preservatives.
Immunogen:
KLH-conjugated GD1a ganglioside.
Quantity:
100 μg
Research Discipline:
Neuroscience
Test Specificity:
GD1a ganglioside. The antibody shows approximately 10% reactivity to GalNAc-GD1a and GT1aα. Preferentially binds to motor myelinated fibers in cross-sections of ventral roots and sciatic nerves.
Content And Storage:
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles
Isotype:
IgG1 κ
Antigen: GT1b Ganglioside
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Ascites
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Ascites
Applications: Immunohistochemistry
Clone: GT1b-2b
Formulation: Liquid. Contains no preservative.
Immunogen: Purified GT1b ganglioside
Quantity: 100 μL
Research Discipline: __
Test Specificity: __
Content And Storage: −20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG2b
Antigen:
GT1b Ganglioside
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Ascites
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Ascites
Applications:
Immunohistochemistry
Clone:
GT1b-2b
Formulation:
Liquid. Contains no preservative.
Immunogen:
Purified GT1b ganglioside
Quantity:
100 μL
Research Discipline:
__
Test Specificity:
__
Content And Storage:
−20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG2b
Antigen: CA125/MUC16
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein A or G purified from ascites
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Flow Cytometry, CyTOF, Immunocytochemistry
Clone: 986808
Formulation: Lyophilized from a 0.2μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2μm filtered solution in PBS.
Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human CA125/MUC-16, Met13360-Gln14347 (Met13472Thr & Gln13957Lys), Accession # NP_078966.2
Quantity: 100 μg
Research Discipline: __
Test Specificity: Detects human CA125/MUC-16 in direct ELISAs.
Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype: IgG2a
Antigen:
CA125/MUC16
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Protein A or G purified from ascites
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, CyTOF, Immunocytochemistry
Clone:
986808
Formulation:
Lyophilized from a 0.2μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2μm filtered solution in PBS.
Immunogen:
Chinese hamster ovary cell line CHO-derived recombinant human CA125/MUC-16, Met13360-Gln14347 (Met13472Thr & Gln13957Lys), Accession # NP_078966.2
Quantity:
100 μg
Research Discipline:
__
Test Specificity:
Detects human CA125/MUC-16 in direct ELISAs.
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype:
IgG2a
Antigen: CA125/MUC16
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Protein A or G purified from ascites
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: CyTOF, Flow Cytometry, Immunohistochemistry
Clone: 986811
Formulation: Lyophilized from a 0.2μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2μm filtered solution in PBS.
Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human CA125/MUC-16, Met13360-Gln14347 (Met13472Thr & Gln13957Lys), Accession # NP_078966.2
Quantity: 100 μg
Research Discipline: __
Test Specificity: Detects human CA125/MUC-16 in direct ELISAs.
Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype: IgG1
Antigen:
CA125/MUC16
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Protein A or G purified from ascites
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
CyTOF, Flow Cytometry, Immunohistochemistry
Clone:
986811
Formulation:
Lyophilized from a 0.2μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2μm filtered solution in PBS.
Immunogen:
Chinese hamster ovary cell line CHO-derived recombinant human CA125/MUC-16, Met13360-Gln14347 (Met13472Thr & Gln13957Lys), Accession # NP_078966.2
Quantity:
100 μg
Research Discipline:
__
Test Specificity:
Detects human CA125/MUC-16 in direct ELISAs.
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype:
IgG1