MABT85925UG
CDCP1 (CD318), Mouse anti-Human, Clone: 8A2, Millipore Sigma™
Manufacturer: MilliporeSigma
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT85925UG-Each-of-1 | In Stock | ₹ 15,999.72 |
MABT85925UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 15,999.72
GST (18%): ₹ 2,879.95
Total Price: ₹ 18,879.67
Antigen
CDCP1 (CD318)
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
CDCP1;TRASK
Immunogen
His-tagged recombinant fragment corresponding to 638 amino acids from the extracellular domain of human CUB domain-containing protein 1.
Quantity
25 μg
Research Discipline
Cell Structure
Test Specificity
Clone 8A2 detects CUB domain-containing protein 1 (CDCP1) in human cells. it targets an epitope within the extracellular domain.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Isotype
IgG2b κ
Applications
Flow Cytometry
Clone
8A2
Dilution
Flow Cytometry Analysis: A representative lot detected CDCP1 (CD318) in one million MDA and MDA KO cells (C ourtesy of the Laboratory of Feng Lin, Ph.D., Cleveland Clinic, Lerner Research Institute, Cleveland OH USA ).
Gene Alias
CUB domain-containing protein 1;Membrane glycoprotein gp140;Subtractive immunization M plus HEp3-associated 135 kDa protein;SIMA135;Transmembrane and associated with src kinases;CD318
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Description
- Anti-CDCP1 (CD318), clone 8A2, Cat
- No
- MABT859, is a mouse monoclonal antibody that detects CUB domain-containing protein 1 (CDCP1) and has been tested for use Flow Cytometry
- CUB domain-containing protein 1 (UniProt: Q9H5V8; also known as Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Transmembrane and associated with Src kinases, CD318) is encoded by the CDCP1 (also known as TRASK) gene (Gene ID: 64866) in human
- CUB domain-containing protein 1 is a single-pass membrane protein that is synthesized with a 29 amino acid signal peptide, which is subsequently cleaved to generate the mature form
- A soluble form of CUB domain-containing protein 1 has also been reported that is produced by proteolytic cleavage at the cell surface
- CUB domain-containing protein 1 is highly expressed in mitotic cells with low expression during interphase
- It is detected at highest levels in skeletal muscle and colon
- Lower expression is reported in kidney, small intestine, placenta, and lung
- It is also reported in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells
- CUB domain-containing protein 1 levels are up-regulated in a number of human tumor cell lines and in colorectal cancer, breast carcinoma and lung cancer
- It is reported to be involved in cell adhesion and cell matrix association and may play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation.
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Antigen: CDCP1 (CD318)
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: CDCP1;TRASK
Immunogen: His-tagged recombinant fragment corresponding to 638 amino acids from the extracellular domain of human CUB domain-containing protein 1.
Quantity: 25 μg
Research Discipline: Cell Structure
Test Specificity: Clone 8A2 detects CUB domain-containing protein 1 (CDCP1) in human cells. it targets an epitope within the extracellular domain.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Flow Cytometry
Clone: 8A2
Dilution: Flow Cytometry Analysis: A representative lot detected CDCP1 (CD318) in one million MDA and MDA KO cells (C ourtesy of the Laboratory of Feng Lin, Ph.D., Cleveland Clinic, Lerner Research Institute, Cleveland OH USA ).
Gene Alias: CUB domain-containing protein 1;Membrane glycoprotein gp140;Subtractive immunization M plus HEp3-associated 135 kDa protein;SIMA135;Transmembrane and associated with src kinases;CD318
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
CDCP1 (CD318)
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
CDCP1;TRASK
Immunogen:
His-tagged recombinant fragment corresponding to 638 amino acids from the extracellular domain of human CUB domain-containing protein 1.
Quantity:
25 μg
Research Discipline:
Cell Structure
Test Specificity:
Clone 8A2 detects CUB domain-containing protein 1 (CDCP1) in human cells. it targets an epitope within the extracellular domain.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Flow Cytometry
Clone:
8A2
Dilution:
Flow Cytometry Analysis: A representative lot detected CDCP1 (CD318) in one million MDA and MDA KO cells (C ourtesy of the Laboratory of Feng Lin, Ph.D., Cleveland Clinic, Lerner Research Institute, Cleveland OH USA ).
Gene Alias:
CUB domain-containing protein 1;Membrane glycoprotein gp140;Subtractive immunization M plus HEp3-associated 135 kDa protein;SIMA135;Transmembrane and associated with src kinases;CD318
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
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Antigen: Podoplanin
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: PDPN;GP36;PSEC0003;PSEC0025
Immunogen: LN229 glioma cells expressing human Podoplanin.
Quantity: 25 μg
Research Discipline: Cell Structure
Test Specificity: Clone LpMab-17 detects podoplanin in human cells. It detects PLAG4 domain. The minimal epitope seunce is shown to be Gly77-Asp82.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: LpMab-17
Dilution: Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Podoplanin in human testis cancer tissue. Flow Cytometry Analysis: A representative lot detected Podoplanin in Flow Cytometry applications (Kato, Y., et. al. (2016). Monoclon Antib Immunodiagn Immunother . 35(2):109-16). Immunohistochemistry Analysis: A representative lot detected Podoplanin in Immunohistochemistry applications (Kato, Y., et. al. (2016). Monoclon Antib Immunodiagn Immunother . 35(2):109-16). Western Blotting Analysis: A representative lot detected Podoplanin in Western Blotting applications (Kato, Y., et. al. (2016). Monoclon Antib Immunodiagn Immunother . 35(2):109-16). ELISA Analysis: A representative lot detected Podoplanin in ELISA applications (Kato, Y., et. al. (2016). Monoclon Antib Immunodiagn Immunother . 35(2):109-16).
Gene Alias: Aggrus;Glycoprotein 36;Gp36;PA2.26 antigen;T1-alpha;T1A
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Podoplanin
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
PDPN;GP36;PSEC0003;PSEC0025
Immunogen:
LN229 glioma cells expressing human Podoplanin.
Quantity:
25 μg
Research Discipline:
Cell Structure
Test Specificity:
Clone LpMab-17 detects podoplanin in human cells. It detects PLAG4 domain. The minimal epitope seunce is shown to be Gly77-Asp82.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
LpMab-17
Dilution:
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Podoplanin in human testis cancer tissue. Flow Cytometry Analysis: A representative lot detected Podoplanin in Flow Cytometry applications (Kato, Y., et. al. (2016). Monoclon Antib Immunodiagn Immunother . 35(2):109-16). Immunohistochemistry Analysis: A representative lot detected Podoplanin in Immunohistochemistry applications (Kato, Y., et. al. (2016). Monoclon Antib Immunodiagn Immunother . 35(2):109-16). Western Blotting Analysis: A representative lot detected Podoplanin in Western Blotting applications (Kato, Y., et. al. (2016). Monoclon Antib Immunodiagn Immunother . 35(2):109-16). ELISA Analysis: A representative lot detected Podoplanin in ELISA applications (Kato, Y., et. al. (2016). Monoclon Antib Immunodiagn Immunother . 35(2):109-16).
Gene Alias:
Aggrus;Glycoprotein 36;Gp36;PA2.26 antigen;T1-alpha;T1A
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified