MS1207P1
Epredia™ Lab Vision™ SREBP-1 (Sterol Regulatory Element Binding Protein-1) Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MS1207P1-Each-of-1 | In Stock | ₹ 64,854.48 |
MS1207P1 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 64,854.48
GST (18%): ₹ 11,673.806
Total Price: ₹ 76,528.286
Antigen
SREBP-1 (Sterol Regulatory Element Binding Protein-1) Ab-1
Classification
Monoclonal
Concentration
200μg/mL
Host Species
Mouse
Quantity
500 μL
Research Discipline
Transcription Regulation
Target Species
Hamster, Human
Isotype
IgG2a κ
Applications
Immunoprecipitation, Western Blot
Clone
2A4
Conjugate
Unconjugated
Immunogen
Recombinant protein encoding N-terminal amino acids 301-407 (the bHLH/leucine zipper domain) of human SREBP-1
Regulatory Status
RUO
Primary or Secondary
Primary
Form
Concentrated
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Description
- SREBP-1 and -2 are transcription factors which participate in the control of cholesterol homeostasis
- SREBPs proteins, which are attached to the endoplasmic reticulum and nuclear envelope, are proteolytically cleaved and thus activated in response to conditions of low cellular sterol
- Upon activation of SREBP-1 or -2, an ∽480-500 amino acid, N-terminal cleavage fragment of these proteins enters the nucleus and activates transcription of enzymes and other proteins required for cholesterol synthesis
- SCA (SREBP-cleavage activity) and caspase-3 proteases cleave SREBPs
- SREBP proteins containing point mutations at caspase-3 cleavage sites (Asp460 in SREBP-1 and Asp468 in SREBP-2) do not become cleaved following induction of apoptosis, suggesting that SREBPs may play some role in apoptotic processes
- Host Species: Mouse Clone: 2A4 Isotype: IgG1/κ Species Reactivity: Human and Hamster
- Others not known
- Epitope: aa 301-407 Immunogen: Recombinant protein encoding N-terminal amino acids 301-407 (the bHLH/leucine zipper domain) of human SREBP-1 Molecular Weight: 125kDa (precursor) and 60-70kDa (cleaved) Positive Control: HeLa and IMR5 cells Cellular Localization: Cytoplasmic and nuclear Recommended for: Western Blotting Immunoprecipitation (Not verified) Note: USA: RUO; Int'l: RUO
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Antigen: SREBP-1 (Sterol Regulatory Element Binding Protein-1) Ab-1
Classification: Monoclonal
Concentration: 200μg/mL
Host Species: Mouse
Quantity: 500 μL
Research Discipline: Transcription Regulation
Target Species: Hamster, Human
Isotype: IgG2a κ
Applications: Immunoprecipitation, Western Blot
Clone: 2A4
Conjugate: Unconjugated
Immunogen: Recombinant protein encoding N-terminal amino acids 301-407 (the bHLH/leucine zipper domain) of human SREBP-1
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
SREBP-1 (Sterol Regulatory Element Binding Protein-1) Ab-1
Classification:
Monoclonal
Concentration:
200μg/mL
Host Species:
Mouse
Quantity:
500 μL
Research Discipline:
Transcription Regulation
Target Species:
Hamster, Human
Isotype:
IgG2a κ
Applications:
Immunoprecipitation, Western Blot
Clone:
2A4
Conjugate:
Unconjugated
Immunogen:
Recombinant protein encoding N-terminal amino acids 301-407 (the bHLH/leucine zipper domain) of human SREBP-1
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: SREBP-1 (Sterol Regulatory Element Binding Protein-1) Ab-1
Classification: Monoclonal
Concentration: 1mg/mL
Host Species: Mouse
Quantity: 100 μL
Research Discipline: Transcription Regulation
Target Species: Hamster, Human
Isotype: IgG2a κ
Applications: Immunoprecipitation, Western Blot
Clone: 2A4
Conjugate: Unconjugated
Immunogen: Recombinant protein encoding N-terminal amino acids 301-407 (the bHLH/leucine zipper domain) of human SREBP-1
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
SREBP-1 (Sterol Regulatory Element Binding Protein-1) Ab-1
Classification:
Monoclonal
Concentration:
1mg/mL
Host Species:
Mouse
Quantity:
100 μL
Research Discipline:
Transcription Regulation
Target Species:
Hamster, Human
Isotype:
IgG2a κ
Applications:
Immunoprecipitation, Western Blot
Clone:
2A4
Conjugate:
Unconjugated
Immunogen:
Recombinant protein encoding N-terminal amino acids 301-407 (the bHLH/leucine zipper domain) of human SREBP-1
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: SREBP-1 (Sterol Regulatory Element Binding Protein-1) Ab-1
Classification: Monoclonal
Concentration: 1mg/mL
Host Species: Mouse
Quantity: 200 μL
Research Discipline: Transcription Regulation
Target Species: Hamster, Human
Isotype: IgG2a κ
Applications: Immunoprecipitation, Western Blot
Clone: 2A4
Conjugate: Unconjugated
Immunogen: Recombinant protein encoding N-terminal amino acids 301-407 (the bHLH/leucine zipper domain) of human SREBP-1
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
SREBP-1 (Sterol Regulatory Element Binding Protein-1) Ab-1
Classification:
Monoclonal
Concentration:
1mg/mL
Host Species:
Mouse
Quantity:
200 μL
Research Discipline:
Transcription Regulation
Target Species:
Hamster, Human
Isotype:
IgG2a κ
Applications:
Immunoprecipitation, Western Blot
Clone:
2A4
Conjugate:
Unconjugated
Immunogen:
Recombinant protein encoding N-terminal amino acids 301-407 (the bHLH/leucine zipper domain) of human SREBP-1
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: Vinculin Ab-1
Classification: Monoclonal
Concentration: 200μg/mL
Host Species: Mouse
Quantity: 1 mL
Research Discipline: Cytoskeletal Protein
Target Species: Human
Isotype: IgG
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: VLN01
Conjugate: Unconjugated
Immunogen: Semi-purified vinculin
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
Vinculin Ab-1
Classification:
Monoclonal
Concentration:
200μg/mL
Host Species:
Mouse
Quantity:
1 mL
Research Discipline:
Cytoskeletal Protein
Target Species:
Human
Isotype:
IgG
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
VLN01
Conjugate:
Unconjugated
Immunogen:
Semi-purified vinculin
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated