MS641P1ABX

IGF-1R (α-subunit) Ab-1 Mouse Monoclonal Antibody, Epredia™

Manufacturer: Fischer Scientific

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Antigen

IGF-1R (alpha-Subunit) Ab-1

Classification

Monoclonal

Concentration

1mg/mL

Host Species

Mouse

Quantity

100 μL

Research Discipline

Neuroscience

Target Species

Human

Isotype

IgG1

Applications

Immunoprecipitation

Clone

24-31

Conjugate

Unconjugated

Immunogen

IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA

Regulatory Status

RUO

Primary or Secondary

Primary

Form

Concentrated

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Description

  • IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of α- and Β-subunits, which are disulfide-linked in a Β-α-α-Β configuration in the mature receptor
  • The α-subunit is completely extracellular, while the Β-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity
  • Host Species: Mouse Clone: 24-31 Isotype: IgG1 Species Reactivity: Human
  • Weakly reacts with Rabbit
  • Does not react with rat
  • Pig unknown
  • Epitope: aa 283-440 (exon 4-6) Immunogen: IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA Molecular Weight: 125kDa Positive Control: Placenta or Breast CA Cellular Localization: Membrane Recommended for: Western Blotting (Not suitable) Immunoprecipitation ELISA Acts as a Weak IGF-like Agonist in Bioassays (Thymidine incorporation into DNA) Does Not Significantly Inhibit IGF-1 Binding Note: USA: RUO; Int'l: RUO

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Fischer Scientific

MS641P1ABX

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Antigen:
IGF-1R (alpha-Subunit) Ab-1

Classification:
Monoclonal

Concentration:
1mg/mL

Host Species:
Mouse

Quantity:
100 μL

Research Discipline:
Neuroscience

Target Species:
Human

Isotype:
IgG1

Applications:
Immunoprecipitation

Clone:
24-31

Conjugate:
Unconjugated

Immunogen:
IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Concentrated

Img

Fischer Scientific

MS641PABX

--


Antigen:
IGF-1R (alpha-Subunit) Ab-1

Classification:
Monoclonal

Concentration:
1mg/mL

Host Species:
Mouse

Quantity:
200 μL

Research Discipline:
Neuroscience

Target Species:
Human

Isotype:
IgG1

Applications:
Immunoprecipitation

Clone:
24-31

Conjugate:
Unconjugated

Immunogen:
IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Concentrated

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Fischer Scientific

MS660P

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Antigen:
p170/p-Glycoprotein/MDR Ab-2

Classification:
Monoclonal

Concentration:
200μg/mL

Host Species:
Mouse

Quantity:
1 mL

Research Discipline:
Cancer and Tumor Biology

Target Species:
Hamster, Human

Isotype:
IgG1

Applications:
Immunofluorescence, Western Blot

Clone:
F4

Conjugate:
Unconjugated

Immunogen:
Human and hamster drug-resistant viable cells followed by crude plasma membranes

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Concentrated

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Antigen:
p170/p-Glycoprotein/MDR Ab-2

Classification:
Monoclonal

Concentration:
200μg/mL

Host Species:
Mouse

Quantity:
500 μL

Research Discipline:
Cancer and Tumor Biology

Target Species:
Hamster, Human

Isotype:
IgG1

Applications:
Immunofluorescence, Western Blot

Clone:
F4

Conjugate:
Unconjugated

Immunogen:
Human and hamster drug-resistant viable cells followed by crude plasma membranes

Regulatory Status:
RUO

Primary or Secondary:
Primary

Form:
Concentrated