MS664B
LRP/MVP (Major Vault Protein) Ab-2 Mouse Monoclonal Antibody, Epredia™
Manufacturer: Fischer Scientific
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Antigen
LRP/MVP (Major Vault Protein) Ab-2
Classification
Monoclonal
Concentration
200μg/mL
Host Species
Mouse
Quantity
1 mL
Research Discipline
Cancer and Tumor Biology
Target Species
Human, Rat
Isotype
IgG2a κ
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
1032
Conjugate
Biotin
Immunogen
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Regulatory Status
RUO
Primary or Secondary
Primary
Form
Concentrated
Related Products
Description
- Major vault protein (MVP) is identical to lung-resistance related protein (LRP)
- Its shape is reminiscent of the nucleopore central plug
- Treatment of cells with estradiol increases the amount of MVP in nuclear extract
- The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate
- Antibodies to progesterone and glucocorticoid receptors are also able to co-immunoprecipitate the MVP
- Reportedly, the lung-resistance related protein (LRP) is identical to human MVP
- LRP is overexpressed in many neoplastic tissues and cell lines indicating a poor response to chemotherapy
- Host Species: Mouse Clone: 1032 Isotype: IgG1/κ Species Reactivity: Human and Rat
- Others not known
- Epitope: Not determined Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells Molecular Weight: 104-110kDa Positive Control: SKBR-3 cells, Breast tumors Cellular Localization: Cytoplasmic Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation (Native verified) Gel Supershift Flow Cytometry Note: USA: RUO; Int'l: RUO
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Antigen: LRP/MVP (Major Vault Protein) Ab-2
Classification: Monoclonal
Concentration: 200μg/mL
Host Species: Mouse
Quantity: 1 mL
Research Discipline: Cancer and Tumor Biology
Target Species: Human, Rat
Isotype: IgG2a κ
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 1032
Conjugate: Biotin
Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
LRP/MVP (Major Vault Protein) Ab-2
Classification:
Monoclonal
Concentration:
200μg/mL
Host Species:
Mouse
Quantity:
1 mL
Research Discipline:
Cancer and Tumor Biology
Target Species:
Human, Rat
Isotype:
IgG2a κ
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
1032
Conjugate:
Biotin
Immunogen:
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: LRP/MVP (Major Vault Protein) Ab-2
Classification: Monoclonal
Concentration: 200μg/mL
Host Species: Mouse
Quantity: 100 μL
Research Discipline: Cancer and Tumor Biology
Target Species: Human, Rat
Isotype: IgG2a κ
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 1032
Conjugate: Biotin
Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
LRP/MVP (Major Vault Protein) Ab-2
Classification:
Monoclonal
Concentration:
200μg/mL
Host Species:
Mouse
Quantity:
100 μL
Research Discipline:
Cancer and Tumor Biology
Target Species:
Human, Rat
Isotype:
IgG2a κ
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
1032
Conjugate:
Biotin
Immunogen:
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: LRP/MVP (Major Vault Protein) Ab-2
Classification: Monoclonal
Concentration: 200μg/mL
Host Species: Mouse
Quantity: 500 μL
Research Discipline: Cancer and Tumor Biology
Target Species: Human, Rat
Isotype: IgG2a κ
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 1032
Conjugate: Biotin
Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
LRP/MVP (Major Vault Protein) Ab-2
Classification:
Monoclonal
Concentration:
200μg/mL
Host Species:
Mouse
Quantity:
500 μL
Research Discipline:
Cancer and Tumor Biology
Target Species:
Human, Rat
Isotype:
IgG2a κ
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
1032
Conjugate:
Biotin
Immunogen:
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated
Antigen: LRP/MVP (Major Vault Protein) Ab-2
Classification: Monoclonal
Concentration: 200μg/mL
Host Species: Mouse
Quantity: 1 mL
Research Discipline: Cancer and Tumor Biology
Target Species: Human, Rat
Isotype: IgG2a κ
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 1032
Conjugate: Unconjugated
Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Concentrated
Antigen:
LRP/MVP (Major Vault Protein) Ab-2
Classification:
Monoclonal
Concentration:
200μg/mL
Host Species:
Mouse
Quantity:
1 mL
Research Discipline:
Cancer and Tumor Biology
Target Species:
Human, Rat
Isotype:
IgG2a κ
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
1032
Conjugate:
Unconjugated
Immunogen:
Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Concentrated