MS738R7

p53 Ab-8 Mouse Monoclonal Antibody, Epredia™

Manufacturer: Fischer Scientific

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Antigen

p53 Ab-8

Classification

Monoclonal

Concentration

Host Species

Mouse

Quantity

7 mL

Research Discipline

Cancer and Tumor Biology

Target Species

Human

Isotype

IgG2a, IgG2b

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

DO-7 + BP53-12

Conjugate

Unconjugated

Immunogen

Recombinant human p53 protein

Regulatory Status

IVD

Primary or Secondary

Primary

Form

Prediluted

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Description

  • Description p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis
  • It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair
  • Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma
  • Host Species: Mouse Clone: DO-7 + BP53-12 Isotype: IgG2b + IgG2a Species Reactivity: Human
  • Others not known
  • Epitope: aa 37-45 and aa 20-25 Immunogen: Recombinant human p53 protein Molecular Weight: 53kDa Positive Control: MDA-231, SKBR-3 cells or Colon CA Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting Immunoprecipitation (Native and denatured)

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Fischer Scientific

MS738R7

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Antigen:
p53 Ab-8

Classification:
Monoclonal

Concentration:

Host Species:
Mouse

Quantity:
7 mL

Research Discipline:
Cancer and Tumor Biology

Target Species:
Human

Isotype:
IgG2a, IgG2b

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
DO-7 + BP53-12

Conjugate:
Unconjugated

Immunogen:
Recombinant human p53 protein

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Prediluted

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MS741P

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Antigen:
Epithelial Membrane Antigen/EMA Ab-3

Classification:
Monoclonal

Concentration:
200μg/mL

Host Species:
Mouse

Quantity:
1 mL

Research Discipline:
Oncogenesis

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
E29

Conjugate:
Unconjugated

Immunogen:
Delipidated extract of human milk fat globule membranes

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

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Antigen:
Epithelial Membrane Antigen/EMA Ab-3

Classification:
Monoclonal

Concentration:
200μg/mL

Host Species:
Mouse

Quantity:
100 μL

Research Discipline:
Oncogenesis

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
E29

Conjugate:
Unconjugated

Immunogen:
Delipidated extract of human milk fat globule membranes

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated

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Antigen:
Epithelial Membrane Antigen/EMA Ab-3

Classification:
Monoclonal

Concentration:
200μg/mL

Host Species:
Mouse

Quantity:
500 μL

Research Discipline:
Oncogenesis

Target Species:
Human

Isotype:
IgG2a κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
E29

Conjugate:
Unconjugated

Immunogen:
Delipidated extract of human milk fat globule membranes

Regulatory Status:
IVD

Primary or Secondary:
Primary

Form:
Concentrated