MS1511R7
Pds1 Ab-1 Mouse Monoclonal Antibody, Epredia™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MS1511R7-Each-of-1 | In Stock | ₹ 46,630.20 |
MS1511R7 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,630.20
GST (18%): ₹ 8,393.436
Total Price: ₹ 55,023.636
Antigen
Pds1 Ab-1
Classification
Monoclonal
Conjugate
Unconjugated
Immunogen
Human recombinant full length Pds1 protein
Regulatory Status
RUO
Primary or Secondary
Primary
Form
Prediluted
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
DCS-280
Host Species
Mouse
Quantity
7 mL
Research Discipline
Cancer and Tumor Biology
Target Species
Human
Isotype
IgG2a κ
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Description
- Pds1 is an anaphase inhibitor and plays important role in DNA damage and spindle check point pathways
- Pds1 inhibits sister chromatid separation by binding and inhibiting Esp1, cystein protease that causes cleavage of the cohesin Scc1 that binds the sister chromatids together
- Pds1 is responsible for targeting of Esp1 to nucleus and its binding to the spindle
- Degradation of Pds1 occurs shortly before anaphase, which liberates Esp1 and is a prerequisite for anaphase entry
- Pds1 is targeted for degradation by ubiquitination mediated by cyclosome/anaphase-promoting complex (APC) functioning as a ubiquitin ligase
- In response to DNA damage Chk1 phosphorylates Pds1 to stabilize it against the APC mediated destruction, hence preventing the entry of such a cell into anaphase
- Host Species: Mouse Clone: DCS-280 Isotype: IgG2a/κ Species Reactivity: Human
- Others not known
- Epitope: Not determined Immunogen: Human recombinant full-length Pds1 protein Molecular Weight: 42kDa Positive Control: HeLa cells, Tonsil Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting (Not verified) Note: USA: RUO; Int'l: RUO
Compare Similar Items
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Antigen: Pds1 Ab-1
Classification: Monoclonal
Conjugate: Unconjugated
Immunogen: Human recombinant full length Pds1 protein
Regulatory Status: RUO
Primary or Secondary: Primary
Form: Prediluted
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: DCS-280
Host Species: Mouse
Quantity: 7 mL
Research Discipline: Cancer and Tumor Biology
Target Species: Human
Isotype: IgG2a κ
Antigen:
Pds1 Ab-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Immunogen:
Human recombinant full length Pds1 protein
Regulatory Status:
RUO
Primary or Secondary:
Primary
Form:
Prediluted
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
DCS-280
Host Species:
Mouse
Quantity:
7 mL
Research Discipline:
Cancer and Tumor Biology
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD4 Ab-8
Classification: Monoclonal
Conjugate: Unconjugated
Immunogen: Stimulated human leukocytes
Regulatory Status: IVD
Primary or Secondary: Primary
Form: Prediluted
Applications: Immunohistochemistry (Paraffin)
Clone: 4B12
Host Species: Mouse
Quantity: 1 mL
Research Discipline: T-Cell
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD4 Ab-8
Classification:
Monoclonal
Conjugate:
Unconjugated
Immunogen:
Stimulated human leukocytes
Regulatory Status:
IVD
Primary or Secondary:
Primary
Form:
Prediluted
Applications:
Immunohistochemistry (Paraffin)
Clone:
4B12
Host Species:
Mouse
Quantity:
1 mL
Research Discipline:
T-Cell
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD4 Ab-8
Classification: Monoclonal
Conjugate: Unconjugated
Immunogen: Stimulated human leukocytes
Regulatory Status: IVD
Primary or Secondary: Primary
Form: Prediluted
Applications: Immunohistochemistry (Paraffin)
Clone: 4B12
Host Species: Mouse
Quantity: 7 mL
Research Discipline: T-Cell
Target Species: Human
Isotype: IgG2a κ
Antigen:
CD4 Ab-8
Classification:
Monoclonal
Conjugate:
Unconjugated
Immunogen:
Stimulated human leukocytes
Regulatory Status:
IVD
Primary or Secondary:
Primary
Form:
Prediluted
Applications:
Immunohistochemistry (Paraffin)
Clone:
4B12
Host Species:
Mouse
Quantity:
7 mL
Research Discipline:
T-Cell
Target Species:
Human
Isotype:
IgG2a κ
Antigen: CD4 Ab-8
Classification: Monoclonal
Conjugate: Unconjugated
Immunogen: Stimulated human leukocytes
Regulatory Status: IVD
Primary or Secondary: Primary
Form: Ready-to-Use
Applications: Immunohistochemistry (Paraffin)
Clone: 4B12
Host Species: Mouse
Quantity: 12 mL
Research Discipline: T-Cell
Target Species: __
Isotype: __
Antigen:
CD4 Ab-8
Classification:
Monoclonal
Conjugate:
Unconjugated
Immunogen:
Stimulated human leukocytes
Regulatory Status:
IVD
Primary or Secondary:
Primary
Form:
Ready-to-Use
Applications:
Immunohistochemistry (Paraffin)
Clone:
4B12
Host Species:
Mouse
Quantity:
12 mL
Research Discipline:
T-Cell
Target Species:
__
Isotype:
__