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N1064359PC7

SerpinB9 Antibody (7D8), PE/Cy7, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N1064359PC7-Each-of-1 In Stock ₹ 58,351.92

N1064359PC7 - Each of 1

₹ 58,351.92

In Stock

Quantity

1

Base Price: ₹ 58,351.92

GST (18%): ₹ 10,503.346

Total Price: ₹ 68,855.266

Antigen

SerpinB9

Classification

Monoclonal

Conjugate

PE-Cyanine7

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

SERPINB9

Immunogen

Recombinant PI-9 produced in P. pastoris.

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

7D8

Dilution

Flow Cytometry

Gene Alias

CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Host Species

Mouse

Purification Method

Protein G purified

Research Discipline

Apoptosis, Immunology

Gene ID (Entrez)

5272.0

Target Species

Human, Mouse (Negative), Porcine (Negative)

Isotype

IgG1

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Description

  • SerpinB9 Monoclonal specifically detects SerpinB9 in Human, Mouse (Negative), Porcine (Negative) samples
  • It is validated for Flow Cytometry.

Compare Similar Items

Show Difference

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Novus Biologicals

N1064359PC7

--

Antigen:
SerpinB9
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
SERPINB9
Immunogen:
Recombinant PI-9 produced in P. pastoris.
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
7D8
Dilution:
Flow Cytometry
Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9
Host Species:
Mouse
Purification Method:
Protein G purified
Research Discipline:
Apoptosis, Immunology
Gene ID (Entrez):
5272.0
Target Species:
Human, Mouse (Negative), Porcine (Negative)
Isotype:
IgG1

Img

Novus Biologicals

N1064360A32

--

Antigen:
CD19
Classification:
Monoclonal
Conjugate:
Alexa Fluor 532
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
CD19
Immunogen:
Human EB-4 Burkitt lymphoma cell line.
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
NB100-64360 recognizes human CD19, a 95kD cell surface glycoprotein, which is expressed on cells of the B cell lineage and follicular dendritic cells but absent on plasma cells. CD19 is an important signal transduction molecule which is involved in the regulation of B lymphocyte development, activation and differentiation.
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry
Clone:
Bu12
Dilution:
Flow Cytometry
Gene Alias:
B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Host Species:
Mouse
Purification Method:
__
Research Discipline:
__
Gene ID (Entrez):
930
Target Species:
Human
Isotype:
IgG1

Img

Novus Biologicals

N1064360A70

--

Antigen:
CD19
Classification:
Monoclonal
Conjugate:
Alexa Fluor 750
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
CD19
Immunogen:
Human EB-4 Burkitt lymphoma cell line.
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
NB100-64360 recognizes human CD19, a 95kD cell surface glycoprotein, which is expressed on cells of the B cell lineage and follicular dendritic cells but absent on plasma cells. CD19 is an important signal transduction molecule which is involved in the regulation of B lymphocyte development, activation and differentiation.
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry
Clone:
Bu12
Dilution:
Flow Cytometry
Gene Alias:
B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Host Species:
Mouse
Purification Method:
__
Research Discipline:
__
Gene ID (Entrez):
930
Target Species:
Human
Isotype:
IgG1

Img

Novus Biologicals

N1064360A94

--

Antigen:
CD19
Classification:
Monoclonal
Conjugate:
Alexa Fluor 594
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
CD19
Immunogen:
Human EB-4 Burkitt lymphoma cell line.
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
NB100-64360 recognizes human CD19, a 95kD cell surface glycoprotein, which is expressed on cells of the B cell lineage and follicular dendritic cells but absent on plasma cells. CD19 is an important signal transduction molecule which is involved in the regulation of B lymphocyte development, activation and differentiation.
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry
Clone:
Bu12
Dilution:
Flow Cytometry
Gene Alias:
B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Host Species:
Mouse
Purification Method:
__
Research Discipline:
__
Gene ID (Entrez):
930
Target Species:
Human
Isotype:
IgG1