SerpinB9 Antibody (7D8), Alexa Fluor™ 750, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | N106439A70-Each-of-1 | In Stock | ₹ 53,218.32 |
N106439A70 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,218.32
GST (18%): ₹ 9,579.298
Total Price: ₹ 62,797.618
Antigen
SerpinB9
Classification
Monoclonal
Conjugate
Alexa Fluor 750
Formulation
50 mM sodium borate with 0.05% sodium azide
Gene Symbols
SERPINB9
Immunogen
Recombinant PI-9 produced in P. pastoris.
Primary or Secondary
Primary
Test Specificity
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD
Content And Storage
Store at 4°C in the dark.
Applications
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone
7D8
Dilution
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9
Host Species
Mouse
Quantity
0.1 mL
Gene ID (Entrez)
5272
Target Species
Human, Mouse, Porcine
Isotype
IgG1
Related Products
Description
- SerpinB9 Monoclonal specifically detects SerpinB9 in Human, Mouse (Negative), Porcine (Negative) samples
- It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Compare Similar Items
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Antigen: SerpinB9
Classification: Monoclonal
Conjugate: Alexa Fluor 750
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: SERPINB9
Immunogen: Recombinant PI-9 produced in P. pastoris.
Primary or Secondary: Primary
Test Specificity: NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kD
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: 7D8
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): 5272
Target Species: Human, Mouse, Porcine
Isotype: IgG1
Antigen: E. Coli J5 LPS
Classification: Monoclonal
Conjugate: Alexa Fluor 532
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: __
Immunogen: E. coli J5 cells.
Primary or Secondary: Primary
Test Specificity: This is specific for E. coli J5 LPS. It has also been found to react with K. pneumoniae, S. sonnei and S. typhimurium.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, ELISA
Clone: 2D7/1
Dilution: Western Blot, ELISA
Gene Alias: Escherichia coli
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): __
Target Species: Bacteria
Isotype: IgG2b
Antigen: E. Coli J5 LPS
Classification: Monoclonal
Conjugate: Alexa Fluor 594
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: __
Immunogen: E. coli J5 cells.
Primary or Secondary: Primary
Test Specificity: This is specific for E. coli J5 LPS. It has also been found to react with K. pneumoniae, S. sonnei and S. typhimurium.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, ELISA
Clone: 2D7/1
Dilution: Western Blot, ELISA
Gene Alias: Escherichia coli
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): __
Target Species: Bacteria
Isotype: IgG2b