N233132P594

NCAM-1/CD56 Antibody (123C3.D5), PE/Atto594, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N233132P594-Each-of-1 In Stock ₹ 63,571.08

N233132P594 - Each of 1

₹ 63,571.08

In Stock

Quantity

1

Base Price: ₹ 63,571.08

GST (18%): ₹ 11,442.794

Total Price: ₹ 75,013.874

Antigen

NCAM-1/CD56

Classification

Monoclonal

Conjugate

PE/ATTO 594

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

NCAM1

Immunogen

Membrane preparation of a small cell lung carcinoma.

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

123C3.D5

Dilution

Flow Cytometry

Gene Alias

CD56, CD56/ NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers

Gene ID (Entrez)

4684.0

Target Species

Human, Rat, Zebrafish

Isotype

IgG1 κ

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Description

  • NCAM-1/CD56 Monoclonal specifically detects NCAM-1/CD56 in Human, Rat samples
  • It is validated for Flow Cytometry.

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Novus Biologicals

N233132P594

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Antigen:
NCAM-1/CD56

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
NCAM1

Immunogen:
Membrane preparation of a small cell lung carcinoma.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
123C3.D5

Dilution:
Flow Cytometry

Gene Alias:
CD56, CD56/ NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers

Gene ID (Entrez):
4684.0

Target Species:
Human, Rat, Zebrafish

Isotype:
IgG1 κ

Img

Novus Biologicals

N233132PEC5

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Antigen:
NCAM-1/CD56

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
NCAM1

Immunogen:
Membrane preparation of a small cell lung carcinoma.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
123C3.D5

Dilution:
Flow Cytometry

Gene Alias:
CD56, CD56/ NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Membrane Vesicle Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers

Gene ID (Entrez):
4684.0

Target Species:
Human, Rat, Zebrafish

Isotype:
IgG1 κ

Img

Novus Biologicals

N233138J549

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Antigen:
Cyclin D1

Classification:
Monoclonal

Conjugate:
Janelia Fluor 549

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
CCND1

Immunogen:
Human full length recombinant cyclin D1 protein (Uniprot: P24385)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.

Content And Storage:
Store at 4°C in the dark.

Applications:
ELISA

Clone:
DCS-6

Dilution:
ELISA

Gene Alias:
B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Cell Cycle and Replication, Core ESC Like Genes, mTOR Pathway, Stem Cell Markers, Wnt Signaling Pathway

Gene ID (Entrez):
595.0

Target Species:
Human, Mouse, Rat, Primate

Isotype:
IgG2a κ

Img

Novus Biologicals

N233140J549

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Antigen:
CD43/Sialophorin

Classification:
Monoclonal

Conjugate:
Janelia Fluor 549

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
SPN

Immunogen:
Myeloblastic KG1 cells were used as the immunogen for this antibody.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43 [Workshop IV]. Epitope of monoclonal antibody Bra7G is clearly different from that of monoclonal antibody DF-T1, called b as opposed to a for DF-T1. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
DF-T1

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43)

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
B Cell Development and Differentiation Markers, Immunology

Gene ID (Entrez):
6693.0

Target Species:
Human

Isotype:
IgG1 κ