N234507P594
Integrin beta 4/CD104 Antibody (UM-A9), PE/Atto594, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | N234507P594-Each-of-1 | In Stock | ₹ 60,448.14 |
N234507P594 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 60,448.14
GST (18%): ₹ 10,880.665
Total Price: ₹ 71,328.805
Antigen
Integrin beta 4/CD104
Classification
Monoclonal
Conjugate
PE/ATTO 594
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
ITGB4
Immunogen
Human squamous cell carcinoma (UM-SCC1)
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Content And Storage
Store at 4°C in the dark. Do not freeze.
Applications
Flow Cytometry
Clone
UM-A9
Dilution
Flow Cytometry
Gene Alias
CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Adaptive Immunity, Immunology, Phospho Specific, Signal Transduction
Gene ID (Entrez)
3691.0
Target Species
Human
Isotype
IgG2a κ
Related Products
Description
- Integrin beta 4/CD104 Monoclonal specifically detects Integrin beta 4/CD104 in Human samples
- It is validated for Flow Cytometry.
Compare Similar Items
Show Difference
Antigen: Integrin beta 4/CD104
Classification: Monoclonal
Conjugate: PE/ATTO 594
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: ITGB4
Immunogen: Human squamous cell carcinoma (UM-SCC1)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: UM-A9
Dilution: Flow Cytometry
Gene Alias: CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Adaptive Immunity, Immunology, Phospho Specific, Signal Transduction
Gene ID (Entrez): 3691.0
Target Species: Human
Isotype: IgG2a κ
Antigen:
Integrin beta 4/CD104
Classification:
Monoclonal
Conjugate:
PE/ATTO 594
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
ITGB4
Immunogen:
Human squamous cell carcinoma (UM-SCC1)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
UM-A9
Dilution:
Flow Cytometry
Gene Alias:
CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, Immunology, Phospho Specific, Signal Transduction
Gene ID (Entrez):
3691.0
Target Species:
Human
Isotype:
IgG2a κ
Antigen: Integrin beta 4/CD104
Classification: Monoclonal
Conjugate: PE-Cyanine5.5
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: ITGB4
Immunogen: Human squamous cell carcinoma (UM-SCC1)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: UM-A9
Dilution: Flow Cytometry
Gene Alias: CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Adaptive Immunity, Immunology, Phospho Specific, Signal Transduction
Gene ID (Entrez): 3691.0
Target Species: Human
Isotype: IgG2a κ
Antigen:
Integrin beta 4/CD104
Classification:
Monoclonal
Conjugate:
PE-Cyanine5.5
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
ITGB4
Immunogen:
Human squamous cell carcinoma (UM-SCC1)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
UM-A9
Dilution:
Flow Cytometry
Gene Alias:
CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, Immunology, Phospho Specific, Signal Transduction
Gene ID (Entrez):
3691.0
Target Species:
Human
Isotype:
IgG2a κ
Antigen: Integrin beta 4/CD104
Classification: Monoclonal
Conjugate: PE-Cyanine7
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: ITGB4
Immunogen: Human squamous cell carcinoma (UM-SCC1)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: UM-A9
Dilution: Flow Cytometry
Gene Alias: CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Adaptive Immunity, Immunology, Phospho Specific, Signal Transduction
Gene ID (Entrez): 3691.0
Target Species: Human
Isotype: IgG2a κ
Antigen:
Integrin beta 4/CD104
Classification:
Monoclonal
Conjugate:
PE-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
ITGB4
Immunogen:
Human squamous cell carcinoma (UM-SCC1)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
UM-A9
Dilution:
Flow Cytometry
Gene Alias:
CD104, CD104 antigen, GP150, integrin beta-4, integrin beta-4 subunit, integrin, beta 4
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, Immunology, Phospho Specific, Signal Transduction
Gene ID (Entrez):
3691.0
Target Species:
Human
Isotype:
IgG2a κ
Antigen: Siglec-3/CD33
Classification: Monoclonal
Conjugate: APC-Cyanine7
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: CD33
Immunogen: Human AML cells
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: WM53
Dilution: Flow Cytometry
Gene Alias: CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, SIGLEC-3, SIGLEC3gp67
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Immunology
Gene ID (Entrez): 945.0
Target Species: Human
Isotype: IgG1 κ
Antigen:
Siglec-3/CD33
Classification:
Monoclonal
Conjugate:
APC-Cyanine7
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CD33
Immunogen:
Human AML cells
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Content And Storage:
Store at 4°C in the dark. Do not freeze.
Applications:
Flow Cytometry
Clone:
WM53
Dilution:
Flow Cytometry
Gene Alias:
CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, SIGLEC-3, SIGLEC3gp67
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Immunology
Gene ID (Entrez):
945.0
Target Species:
Human
Isotype:
IgG1 κ