N2022858PC7

Integrin alpha 4/CD49d Antibody (HP2/1), PE/Cy7, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N2022858PC7-Each-of-1 In Stock ₹ 57,325.20

N2022858PC7 - Each of 1

₹ 57,325.20

In Stock

Quantity

1

Base Price: ₹ 57,325.20

GST (18%): ₹ 10,318.536

Total Price: ₹ 67,643.736

Antigen

Integrin alpha 4/CD49d

Classification

Monoclonal

Conjugate

PE-Cyanine7

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

ITGA4

Immunogen

JM leukaemia line (Human).

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Mouse anti Human CD49d monoclonal antibody, clone HP2/1 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ∽150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer′s patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). Mouse anti human CD49d, clone HP2/1 binds to both intact and the 80kDa fragment of integrin alpha-4. CD49d is expressed on monocytes, T cells, B cells, thymocytes and Langerhans cells (de Graaf et al. 19

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

HP2/1

Dilution

Flow Cytometry

Gene Alias

269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Cancer, Cellular Markers, Cytoskeleton Markers, Phospho Specific

Gene ID (Entrez)

3676.0

Target Species

Human

Isotype

IgG1

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Description

  • Description Integrin alpha 4/CD49d Monoclonal specifically detects Integrin alpha 4/CD49d in Human samples
  • It is validated for Flow Cytometry.

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Show Difference

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Novus Biologicals

N2022858PC7

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Antigen:
Integrin alpha 4/CD49d

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
ITGA4

Immunogen:
JM leukaemia line (Human).

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Mouse anti Human CD49d monoclonal antibody, clone HP2/1 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ∽150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer′s patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). Mouse anti human CD49d, clone HP2/1 binds to both intact and the 80kDa fragment of integrin alpha-4. CD49d is expressed on monocytes, T cells, B cells, thymocytes and Langerhans cells (de Graaf et al. 19

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
HP2/1

Dilution:
Flow Cytometry

Gene Alias:
269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Cellular Markers, Cytoskeleton Markers, Phospho Specific

Gene ID (Entrez):
3676.0

Target Species:
Human

Isotype:
IgG1

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Antigen:
V alpha 24 J alpha 18 TCR

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
__

Immunogen:
Peptide epitope in the CDR3 region of V alpha 24

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
6B11

Dilution:
Flow Cytometry, Flow (Cell Surface)

Gene Alias:
iNKT, iNKT cell, invariant natural killer T cell, invariant NK T cell, invariant NKT cell

Host Species:
Mouse

Purification Method:
Protein G purified

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human

Isotype:
IgG1 κ

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Novus Biologicals

N20267PECY7

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Antigen:
V alpha 24 J alpha 18 TCR

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
__

Immunogen:
Peptide epitope in the CDR3 region of V alpha 24

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
6B11

Dilution:
Flow Cytometry, Flow (Cell Surface)

Gene Alias:
iNKT, iNKT cell, invariant natural killer T cell, invariant NK T cell, invariant NKT cell

Host Species:
Mouse

Purification Method:
Protein G purified

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human

Isotype:
IgG1 κ

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Antigen:
Hepatitis C Virus Core Antigen

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
POLY

Immunogen:
Purified HCV core-GST fusion protein (genotype 1b).

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
C7-50

Dilution:
Flow Cytometry

Gene Alias:
Core protein p19, HCcAg, HCV core antigen, HCV core protein

Host Species:
Mouse

Purification Method:
Affinity Purified

Research Discipline:
Virology Bacteria and Parasites

Gene ID (Entrez):
951475.0

Target Species:
Human, Mouse, Virus

Isotype:
IgG1