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N1202288A70

Integrin alpha 4/CD49d Antibody (HP2/1), Alexa Fluor™ 750, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N1202288A70-Each-of-1 In Stock ₹ 52,191.60

N1202288A70 - Each of 1

₹ 52,191.60

In Stock

Quantity

1

Base Price: ₹ 52,191.60

GST (18%): ₹ 9,394.488

Total Price: ₹ 61,586.088

Antigen

Integrin alpha 4/CD49d

Classification

Monoclonal

Conjugate

Alexa Fluor 750

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

ITGA4

Immunogen

JM leukaemia line (Human).

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Mouse anti Human CD49d monoclonal antibody, clone HP2/1 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ∼150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer′s patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). Mouse anti human CD49d, clone HP2/1 binds to both intact and the 80kDa fragment of integrin alpha-4. CD49d is expressed on monocytes, T cells, B cells, thymocytes and Langerhans cells (de Graaf et al. 199

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)

Clone

HP2/1

Dilution

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen

Gene Alias

269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Cancer, Cellular Markers, Cytoskeleton Markers, Phospho Specific

Gene ID (Entrez)

3676.0

Target Species

Human

Isotype

IgG1

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Description

  • Description Integrin alpha 4/CD49d Monoclonal specifically detects Integrin alpha 4/CD49d in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen.

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Show Difference

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Novus Biologicals

N1202288A70

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Antigen:
Integrin alpha 4/CD49d
Classification:
Monoclonal
Conjugate:
Alexa Fluor 750
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
ITGA4
Immunogen:
JM leukaemia line (Human).
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Mouse anti Human CD49d monoclonal antibody, clone HP2/1 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ∼150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer′s patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). Mouse anti human CD49d, clone HP2/1 binds to both intact and the 80kDa fragment of integrin alpha-4. CD49d is expressed on monocytes, T cells, B cells, thymocytes and Langerhans cells (de Graaf et al. 199
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Clone:
HP2/1
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Gene Alias:
269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Cellular Markers, Cytoskeleton Markers, Phospho Specific
Gene ID (Entrez):
3676.0
Target Species:
Human
Isotype:
IgG1

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Novus Biologicals

N1202736A32

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Antigen:
NUP62
Classification:
Monoclonal
Conjugate:
Alexa Fluor 532
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
NUP62
Immunogen:
O-linked glycoprotein-enriched fraction from rat liver nuclear envelopes raised in Armenian hamsters.
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Detects the nucleoporin p62 O-linked glycoprotein in the p62 complex from rat tissues.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Immunofluorescence
Clone:
RL31
Dilution:
Western Blot, Immunofluorescence
Gene Alias:
DKFZp547L134,62 kDa nucleoporin, FLJ20822, FLJ43869, IBSNp62, MGC841, nuclear pore glycoprotein p62, nucleoporin 62kD, nucleoporin 62kDa, SNDINucleoporin Nup62
Host Species:
Armenian Hamster
Purification Method:
__
Research Discipline:
__
Gene ID (Entrez):
23636
Target Species:
Rat
Isotype:
IgG

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Antigen:
Hepatitis C Virus Core Antigen
Classification:
Monoclonal
Conjugate:
Alexa Fluor 532
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
POLY
Immunogen:
Purified HCV core-GST fusion protein (genotype 1b).
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunofluorescence
Clone:
C7-50
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunofluorescence
Gene Alias:
Core protein p19, HCcAg, HCV core antigen, HCV core protein
Host Species:
Mouse
Purification Method:
__
Research Discipline:
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Gene ID (Entrez):
951475
Target Species:
Human, Mouse, Virus
Isotype:
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Antigen:
Hepatitis C Virus Core Antigen
Classification:
Monoclonal
Conjugate:
Alexa Fluor 594
Formulation:
50 mM sodium borate with 0.05% sodium azide
Gene Symbols:
POLY
Immunogen:
Purified HCV core-GST fusion protein (genotype 1b).
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunofluorescence
Clone:
C7-50
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunofluorescence
Gene Alias:
Core protein p19, HCcAg, HCV core antigen, HCV core protein
Host Species:
Mouse
Purification Method:
__
Research Discipline:
__
Gene ID (Entrez):
951475
Target Species:
Human, Mouse, Virus
Isotype:
IgG1