N247703P594

beta 2-Microglobulin Antibody (SPM617), PE/Atto594, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N247703P594-Each-of-1 In Stock ₹ 60,448.14

N247703P594 - Each of 1

₹ 60,448.14

In Stock

Quantity

1

Base Price: ₹ 60,448.14

GST (18%): ₹ 10,880.665

Total Price: ₹ 71,328.805

Antigen

beta 2-Microglobulin

Classification

Monoclonal

Conjugate

PE/ATTO 594

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

B2M

Immunogen

Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

SPM617

Dilution

Flow Cytometry

Gene Alias

beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez)

567.0

Target Species

Human, Primate

Isotype

IgG1 κ

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Description

  • beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate samples
  • It is validated for Flow Cytometry.

Compare Similar Items

Show Difference

Img

Novus Biologicals

N247703P594

--


Antigen:
beta 2-Microglobulin

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
B2M

Immunogen:
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SPM617

Dilution:
Flow Cytometry

Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez):
567.0

Target Species:
Human, Primate

Isotype:
IgG1 κ

Img

Novus Biologicals

N247703PEC5

--


Antigen:
beta 2-Microglobulin

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
B2M

Immunogen:
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SPM617

Dilution:
Flow Cytometry

Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez):
567.0

Target Species:
Human, Primate

Isotype:
IgG1 κ

Img

Novus Biologicals

N247703PEC7

--


Antigen:
beta 2-Microglobulin

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
B2M

Immunogen:
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Beta2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin′s lymphoma. In urine, increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS, malignant monoclonal plasma cell dyscrasia, solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency, graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy)

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
SPM617

Dilution:
Flow Cytometry

Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez):
567.0

Target Species:
Human, Primate

Isotype:
IgG1 κ

Img

Novus Biologicals

N247704APC7

--


Antigen:
beta 2-Microglobulin

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
B2M

Immunogen:
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769 )

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
B2M/961

Dilution:
Flow Cytometry

Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez):
567.0

Target Species:
Human, Primate

Isotype:
IgG2b κ