N247704P594

beta 2-Microglobulin Antibody (B2M/961), PE/Atto594, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N247704P594-Each-of-1 In Stock ₹ 60,448.14

N247704P594 - Each of 1

₹ 60,448.14

In Stock

Quantity

1

Base Price: ₹ 60,448.14

GST (18%): ₹ 10,880.665

Total Price: ₹ 71,328.805

Antigen

beta 2-Microglobulin

Classification

Monoclonal

Conjugate

PE/ATTO 594

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

B2M

Immunogen

Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769 )

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

B2M/961

Dilution

Flow Cytometry

Gene Alias

beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez)

567.0

Target Species

Human, Primate

Isotype

IgG2b κ

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Description

  • beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate samples
  • It is validated for Flow Cytometry.

Compare Similar Items

Show Difference

Img

Novus Biologicals

N247704P594

--


Antigen:
beta 2-Microglobulin

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
B2M

Immunogen:
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769 )

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
B2M/961

Dilution:
Flow Cytometry

Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez):
567.0

Target Species:
Human, Primate

Isotype:
IgG2b κ

Img

Novus Biologicals

N247704PEC5

--


Antigen:
beta 2-Microglobulin

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
B2M

Immunogen:
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769 )

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
B2M/961

Dilution:
Flow Cytometry

Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez):
567.0

Target Species:
Human, Primate

Isotype:
IgG2b κ

Img

Novus Biologicals

N247704PEC7

--


Antigen:
beta 2-Microglobulin

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
B2M

Immunogen:
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769 )

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
B2M/961

Dilution:
Flow Cytometry

Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez):
567.0

Target Species:
Human, Primate

Isotype:
IgG2b κ

Img

Novus Biologicals

N24770APCY7

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Antigen:
beta 2-Microglobulin

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
B2M

Immunogen:
Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 12kDa, identified as beta-microglobulin. Beta--microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This monoclonal antibody is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. Detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
246-E9.E7 (same as HLA.ABC.m2)

Dilution:
Flow Cytometry

Gene Alias:
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology

Gene ID (Entrez):
567.0

Target Species:
Human, Primate (Negative)

Isotype:
IgG2a κ