Manufacturer: Novus Biologicals
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | N247704P594-Each-of-1 | In Stock | ₹ 60,448.14 |
N247704P594 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 60,448.14
GST (18%): ₹ 10,880.665
Total Price: ₹ 71,328.805
beta 2-Microglobulin
Monoclonal
PE/ATTO 594
PBS with 0.05% Sodium Azide
B2M
Full length recombinant human beta 2-Microglobulin protein (Uniprot: P61769 )
0.1 mL
Primary
Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
Store at 4°C in the dark. Do not freeze.
Flow Cytometry
B2M/961
Flow Cytometry
beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
Mouse
Protein A or G purified
Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
567.0
Human, Primate
IgG2b κ