N247758J646

Calponin 1 Antibody (CNN1/832 + CALP), Janelia Fluor™ 646, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N247758J646-Each-of-1 In Stock ₹ 55,271.76

N247758J646 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Calponin 1

Classification

Monoclonal

Conjugate

Janelia Fluor 646

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

CNN1

Immunogen

Recombinant full-length human Calponin 1 protein (Calponin 1/832); Crude human uterus extract (CALP) (Uniprot: P51911)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this monoclonal antibody reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

CNN1/832 + CALP

Dilution

Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

Basic calponin, calponin 1, basic, smooth muscle, Calponin H1, smooth muscle, calponins, basic, Sm-Calp, SMCCcalponin-1

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Cancer, Cytoskeleton Markers

Gene ID (Entrez)

1264.0

Target Species

Human, Rat

Isotype

IgG1 κ

Related Products

Img

Novus Biologicals

NB008985

--

Img

Novus Biologicals

NB008993

--

Img

Novus Biologicals

NB009006

--

Img

Novus Biologicals

NB009004

--

Img

Novus Biologicals

NB008921

--

Img

Novus Biologicals

NB008923

--

Img

Novus Biologicals

NB008933

--

Img

Novus Biologicals

NB008932

--

Description

  • Calponin 1 Monoclonal specifically detects Calponin 1 in Human, Rat samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

N247758J646

--


Antigen:
Calponin 1

Classification:
Monoclonal

Conjugate:
Janelia Fluor 646

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
CNN1

Immunogen:
Recombinant full-length human Calponin 1 protein (Calponin 1/832); Crude human uterus extract (CALP) (Uniprot: P51911)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this monoclonal antibody reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
CNN1/832 + CALP

Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
Basic calponin, calponin 1, basic, smooth muscle, Calponin H1, smooth muscle, calponins, basic, Sm-Calp, SMCCcalponin-1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Cytoskeleton Markers

Gene ID (Entrez):
1264.0

Target Species:
Human, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

N247759PEC5

--


Antigen:
CCR5

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CCR5

Immunogen:
Human native CCR5 protein (Uniprot: P51681)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Reacts with the N-terminal extracellular domain of CD195. The CC chemokine receptor 5 (CCR5) is a member of the CC-chemokine receptor family, and has the characteristic structure of a 7 transmembrane G protein-coupled receptor (GPCR). CCR5 regulates trafficking and effector functions of memory/effector Th1 cells, macrophages, NK cells, and immature dendritic cells. CCR5 and its ligands play an important role in viral pathogenesis. CCR5 represents the co-receptor for macrophage (M) and dual (T cell and M)-tropic immunodeficiency viruses. Together with the CD4 binding receptor, CCR5 plays a critical role in HIV entry into the target cells. Moreover, the CCR5 ligands macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and RANTES act as endogenous inhibitors of HIV infection, making both CCR5 and its chemokine ligands attractive therapeutic targets for HIV infection. Recent studies have also highlighted the role of CCR5 in a variety of other human diseases, ranging from infectious an

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
12D1

Dilution:
Flow Cytometry

Gene Alias:
C-C CKR-5, C-C motif chemokine receptor 5 A159A, CCCKR5, CC-CKR-5FLJ78003, CCR-5, CD195, CD195 antigen, chemokine (C-C motif) receptor 5, chemokine receptor CCR5, chemr13, CKR5, CKR-5, HIV-1 fusion coreceptor, IDDM22CMKBR5C-C chemokine receptor type 5

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Alzheimers Research, Cancer, Chemokine Research, Chemokines and Cytokines, Cytokine Research, GPCR, Immunology, Innate Immunity, Neurodegeneration, Neuroscience, Phospho Specific, Signal Transduction

Gene ID (Entrez):
1234.0

Target Species:
Human

Isotype:
IgG2a κ

Img

Novus Biologicals

N24775PE594

--


Antigen:
CD90/Thy1

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
THY1

Immunogen:
Human T-lymphoma cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 18-35kDa, identified as CD90 (also known as Thy1). CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kDa) inserted into the cell membrane via a GPI anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblast and stromal cell lines, expressed on all thymocytes and peripheral T cells in mice, but in humans expressed only on small % fetal thymocytes, 10-40% of CD34+ cells in bone marrow, and <1% of CD3+CD4+ lymphocytes in peripheral circulation. It is also expressed by human lymph node HEV endothelium but not other endothelia. Lastly, it is expressed by a limited number of lymphoblastoid and leukemic cell lines.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
AF-9

Dilution:
Flow Cytometry

Gene Alias:
CD90, CD90 antigen, CDw90, FLJ33325, Thy-1 antigen, Thy-1 cell surface antigen, thy-1 membrane glycoprotein, Thy-1 T-cell antigen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Hematopoietic Stem Cell Markers, Hepatic Stem Cell Markers, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Markers

Gene ID (Entrez):
7070.0

Target Species:
Human, Bovine

Isotype:
IgG1 κ

Img

Novus Biologicals

N24775PECY5

--


Antigen:
CD90/Thy1

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
THY1

Immunogen:
Human T-lymphoma cells

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 18-35kDa, identified as CD90 (also known as Thy1). CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kDa) inserted into the cell membrane via a GPI anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblast and stromal cell lines, expressed on all thymocytes and peripheral T cells in mice, but in humans expressed only on small % fetal thymocytes, 10-40% of CD34+ cells in bone marrow, and <1% of CD3+CD4+ lymphocytes in peripheral circulation. It is also expressed by human lymph node HEV endothelium but not other endothelia. Lastly, it is expressed by a limited number of lymphoblastoid and leukemic cell lines.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
AF-9

Dilution:
Flow Cytometry

Gene Alias:
CD90, CD90 antigen, CDw90, FLJ33325, Thy-1 antigen, Thy-1 cell surface antigen, thy-1 membrane glycoprotein, Thy-1 T-cell antigen

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Hematopoietic Stem Cell Markers, Hepatic Stem Cell Markers, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Markers

Gene ID (Entrez):
7070.0

Target Species:
Human, Bovine

Isotype:
IgG1 κ