N247777P594

MCAM/CD146 Antibody (MUC18/1130), PE/Atto594, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 N247777P594-Each-of-1 In Stock ₹ 60,448.14

N247777P594 - Each of 1

₹ 60,448.14

In Stock

Quantity

1

Base Price: ₹ 60,448.14

GST (18%): ₹ 10,880.665

Total Price: ₹ 71,328.805

Antigen

MCAM/CD146

Classification

Monoclonal

Conjugate

PE/ATTO 594

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

MCAM

Immunogen

Recombinant full-length human MCAM/CD146 protein (Uniprot: P43121)

Quantity

0.1 mL

Primary or Secondary

Primary

Test Specificity

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Content And Storage

Store at 4°C in the dark. Do not freeze.

Applications

Flow Cytometry

Clone

MUC18/1130

Dilution

Flow Cytometry

Gene Alias

CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin

Host Species

Mouse

Purification Method

Protein A or G purified

Research Discipline

Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers

Gene ID (Entrez)

4162.0

Target Species

Human

Isotype

IgG1 κ

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Description

  • MCAM/CD146 Monoclonal specifically detects MCAM/CD146 in Human samples
  • It is validated for Flow Cytometry.

Compare Similar Items

Show Difference

Img

Novus Biologicals

N247777P594

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Antigen:
MCAM/CD146

Classification:
Monoclonal

Conjugate:
PE/ATTO 594

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
MCAM

Immunogen:
Recombinant full-length human MCAM/CD146 protein (Uniprot: P43121)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
MUC18/1130

Dilution:
Flow Cytometry

Gene Alias:
CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers

Gene ID (Entrez):
4162.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N247777PEC5

--


Antigen:
MCAM/CD146

Classification:
Monoclonal

Conjugate:
PE-Cyanine5.5

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
MCAM

Immunogen:
Recombinant full-length human MCAM/CD146 protein (Uniprot: P43121)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
MUC18/1130

Dilution:
Flow Cytometry

Gene Alias:
CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers

Gene ID (Entrez):
4162.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N247777PEC7

--


Antigen:
MCAM/CD146

Classification:
Monoclonal

Conjugate:
PE-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
MCAM

Immunogen:
Recombinant full-length human MCAM/CD146 protein (Uniprot: P43121)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry

Clone:
MUC18/1130

Dilution:
Flow Cytometry

Gene Alias:
CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers

Gene ID (Entrez):
4162.0

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

N247778APC7

--


Antigen:
B7-2/CD86

Classification:
Monoclonal

Conjugate:
APC-Cyanine7

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
CD86

Immunogen:
Recombinant human full-length B7-2/CD86 protein (Uniprot: P42081)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 70kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin′s disease.

Content And Storage:
Store at 4°C in the dark. Do not freeze.

Applications:
Flow Cytometry, Immunoassay

Clone:
C86/1146

Dilution:
Flow Cytometry, Knockout Validated

Gene Alias:
Activation B7-2 antigen, B70, B7-2, B7-2 antigen, B-lymphocyte activation antigen B7-2, BU63, CD28 antigen ligand 2, CD28LG2B7-2 antigen), CD86 antigen, CD86 molecule, CTLA-4 counter-receptor B7.2, FUN-1, LAB72, MGC34413, T-lymphocyte activation antigen CD86

Host Species:
Mouse

Purification Method:
Protein A or G purified

Research Discipline:
Adaptive Immunity, B Cell Development and Differentiation Markers, Cell Cycle and Replication, Dendritic Cell Markers, Diabetes Research, Immunology, Myeloid derived Suppressor Cell

Gene ID (Entrez):
942.0

Target Species:
Human, Mouse, Rat

Isotype:
IgG1 κ