MUC1 Antibody (MUC1/967), PE/Atto594, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | N24785PE594-Each-of-1 | In Stock | ₹ 60,448.14 |
N24785PE594 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 60,448.14
GST (18%): ₹ 10,880.665
Total Price: ₹ 71,328.805
Antigen
MUC1
Classification
Monoclonal
Conjugate
PE/ATTO 594
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
MUC1
Immunogen
Human milk-fat globule membranes (HMFGM) (Uniprot: P15941 )
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
This monoclonal antibody recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this monoclonal antibody is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (200kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the monoclonal antibody. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This monoclonal antibody reacts with both normal and malignant epithelia of various tissues including breast and colon.
Content And Storage
Store at 4°C in the dark. Do not freeze.
Applications
Flow Cytometry
Clone
MUC1/967
Dilution
Flow Cytometry
Gene Alias
Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction
Gene ID (Entrez)
4582.0
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- MUC1 Monoclonal specifically detects MUC1 in Human samples
- It is validated for Flow Cytometry.
Compare Similar Items
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Antigen: MUC1
Classification: Monoclonal
Conjugate: PE/ATTO 594
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: MUC1
Immunogen: Human milk-fat globule membranes (HMFGM) (Uniprot: P15941 )
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this monoclonal antibody is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (200kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the monoclonal antibody. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This monoclonal antibody reacts with both normal and malignant epithelia of various tissues including breast and colon.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: MUC1/967
Dilution: Flow Cytometry
Gene Alias: Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction
Gene ID (Entrez): 4582.0
Target Species: Human
Isotype: IgG1 κ
Antigen: VCAM-1/CD106
Classification: Monoclonal
Conjugate: PE-Cyanine5.5
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: VCAM1
Immunogen: Activated human umbilical vein endothelial cells (HUVEC)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This monoclonal antibody inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: B-K9
Dilution: Flow Cytometry
Gene Alias: CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers
Gene ID (Entrez): 7412.0
Target Species: Human, Rat
Isotype: IgG1 κ
Antigen: CD35
Classification: Monoclonal
Conjugate: PE-Cyanine5.5
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: CR1
Immunogen: Recombinant full-length human CD35 protein (Uniprot: P17927)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This monoclonal antibody does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This monoclonal antibody labels follicular dendritic cells and follicular dendritic cell sarcoma.
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: CR1/802
Dilution: Flow Cytometry
Gene Alias: complement component (3b/4b) receptor 1 (Knops blood group), KN
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: __
Gene ID (Entrez): 1378.0
Target Species: Human, Monkey, Baboon
Isotype: IgG1 κ