MUC1 Antibody (SPM492), PE/Atto594, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | N24789PE594-Each-of-1 | In Stock | ₹ 60,704.82 |
N24789PE594 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 60,704.82
GST (18%): ₹ 10,926.868
Total Price: ₹ 71,631.688
Antigen
MUC1
Classification
Monoclonal
Conjugate
PE/ATTO 594
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
MUC1
Immunogen
Breast Cancer Cell line ZR75-1
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
This monoclonal antibody reacts with MUC1. The dominant epitope of this monoclonal antibody has not yet been determined. MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and over expressed abundantly in 90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four c-erbB receptors and localize with c-erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. Antibody to EMA
Content And Storage
Store at 4°C in the dark. Do not freeze.
Applications
Flow Cytometry
Clone
SPM492
Dilution
Flow Cytometry
Gene Alias
Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction
Gene ID (Entrez)
4582.0
Target Species
Human, Mouse
Isotype
IgG1 κ
Related Products
Description
- MUC1 Monoclonal specifically detects MUC1 in Human, Mouse samples
- It is validated for Flow Cytometry.
Compare Similar Items
Show Difference
Antigen: MUC1
Classification: Monoclonal
Conjugate: PE/ATTO 594
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: MUC1
Immunogen: Breast Cancer Cell line ZR75-1
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with MUC1. The dominant epitope of this monoclonal antibody has not yet been determined. MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and over expressed abundantly in 90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four c-erbB receptors and localize with c-erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. Antibody to EMA
Content And Storage: Store at 4°C in the dark. Do not freeze.
Applications: Flow Cytometry
Clone: SPM492
Dilution: Flow Cytometry
Gene Alias: Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction
Gene ID (Entrez): 4582.0
Target Species: Human, Mouse
Isotype: IgG1 κ
Antigen: Myosin heavy chain 11
Classification: Monoclonal
Conjugate: Janelia Fluor 549
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: MYH11
Immunogen: Recombinant human Myosin heavy chain 11 protein (Myosin heavy chain 11/923); Human uterus extract (SMMS-1) (Uniprot: P35749)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: MYH11/923 + SMMS-1
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: AAT4, FAA4, MYH11, MYH11 myosin, heavy chain 11, smooth muscle, SMHC, SMMHC, Smooth muscle myosin heavy chain
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Hypoxia, Stem Cell Markers
Gene ID (Entrez): 4629.0
Target Species: Human, Rat
Isotype: IgG1 κ
Antigen: Myosin heavy chain 11
Classification: Monoclonal
Conjugate: Janelia Fluor 646
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: MYH11
Immunogen: Recombinant human Myosin heavy chain 11 protein (Myosin heavy chain 11/923); Human uterus extract (SMMS-1) (Uniprot: P35749)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: MYH11/923 + SMMS-1
Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: AAT4, FAA4, MYH11, MYH11 myosin, heavy chain 11, smooth muscle, SMHC, SMMHC, Smooth muscle myosin heavy chain
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Hypoxia, Stem Cell Markers
Gene ID (Entrez): 4629.0
Target Species: Human, Rat
Isotype: IgG1 κ