NB013561

p21/CIP1/CDKN1A Antibody (CIP1/2275R) - Azide and BSA Free, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB013561-Each-of-1 In Stock ₹ 57,367.98

NB013561 - Each of 1

₹ 57,367.98

In Stock

Quantity

1

Base Price: ₹ 57,367.98

GST (18%): ₹ 10,326.236

Total Price: ₹ 67,694.216

Antigen

p21/CIP1/CDKN1A

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

10 mM PBS

Gene Symbols

CDKN1A

Immunogen

Recombinant full-length human p21/CIP1/CDKN1A protein (Uniprot: P38936)

Quantity

100 μg

Research Discipline

Apoptosis, Breast Cancer, Cancer, Cell Cycle and Replication, DNA Repair, Phospho Specific

Gene ID (Entrez)

1026

Target Species

Human, Mouse (Negative), Rat (Negative)

Form

Purified

Applications

Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone

CIP1/2275R

Dilution

Western Blot 1 - 2 μg/mL, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias

CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1

Host Species

Rabbit

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This monoclonal antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This monoclonal antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).

Content And Storage

Store at -20 to -80°C. Avoid freeze-thaw cycles.

Isotype

IgG

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Description

  • Description p21/CIP1/CDKN1A Monoclonal specifically detects p21/CIP1/CDKN1A in Human, Mouse (Negative), Rat (Negative) samples
  • It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB013561

--


Antigen:
p21/CIP1/CDKN1A

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
10 mM PBS

Gene Symbols:
CDKN1A

Immunogen:
Recombinant full-length human p21/CIP1/CDKN1A protein (Uniprot: P38936)

Quantity:
100 μg

Research Discipline:
Apoptosis, Breast Cancer, Cancer, Cell Cycle and Replication, DNA Repair, Phospho Specific

Gene ID (Entrez):
1026

Target Species:
Human, Mouse (Negative), Rat (Negative)

Form:
Purified

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
CIP1/2275R

Dilution:
Western Blot 1 - 2 μg/mL, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
CAP20cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, CDKN1melanoma differentiation associated protein 6, CIP1WAF1CDK-interaction protein 1, cyclin-dependent kinase inhibitor 1A (p21, Cip1), MDA6, MDA-6, Melanoma differentiation-associated protein 6, p21, p21CIP1, p21Cip1/Waf1, PIC1, SDI1DNA synthesis inhibitor, wild-type p53-activated fragment 1

Host Species:
Rabbit

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This monoclonal antibody is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdks and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).

Content And Storage:
Store at -20 to -80°C. Avoid freeze-thaw cycles.

Isotype:
IgG

Img

Novus Biologicals

NB013568

--


Antigen:
c-Fos

Classification:
Polyclonal

Conjugate:
Unconjugated

Formulation:
Lyophilized from whole serum

Gene Symbols:
FOS

Immunogen:
A synthetic peptide from human c-Fos protein conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in many other species including rat and mouse.

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Cellular Markers, Hypoxia, Neuronal Cell Markers, Neuroscience, Transcription Factors and Regulators, Tumor Suppressors

Gene ID (Entrez):
2353

Target Species:
Human, Mouse, Rat, Monkey

Form:
__

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
__

Dilution:
Western Blot 1:500, Immunohistochemistry 1:500, Immunohistochemistry-Paraffin 1:500

Gene Alias:
activator protein 1, AP-1, cellular oncogene c-fos, Cellular oncogene fos, c-fos, FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS), FBJ murine osteosarcoma viral oncogene homolog, G0/G1 switch regulatory protein 7, G0S7, proto-oncogene c-Fos, v-fos FBJ murine osteosarcoma viral oncogene homolog

Host Species:
Guinea Pig

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Isotype:
__

Img

Novus Biologicals

NB013574

--


Antigen:
Aquaporin-12A

Classification:
Polyclonal

Conjugate:
Unconjugated

Formulation:
Lyophilized from whole serum

Gene Symbols:
AQP12A

Immunogen:
A synthetic peptide from amino acid region 10-50 of human Aquaporin-12A conjugated to blue carrier protein was used as the antigen.

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
375318

Target Species:
Human, Mouse, Monkey

Form:
__

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
__

Dilution:
Western Blot 1:1000, Immunohistochemistry 1:1000, Immunohistochemistry-Paraffin 1:1000

Gene Alias:
AQP-12, AQP12AQPX2aquaporin X2, aquaporin 12, aquaporin 12A, aquaporin-12A

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Isotype:
__

Img

Novus Biologicals

NB013576

--


Antigen:
Aquaporin-7

Classification:
Polyclonal

Conjugate:
Unconjugated

Formulation:
Lyophilized from whole serum

Gene Symbols:
AQP7

Immunogen:
A synthetic peptide from rat Aquaporin-7 conjugated to blue carrier protein was used as the antigen.

Quantity:
0.1 mL

Research Discipline:
__

Gene ID (Entrez):
364

Target Species:
Mouse, Rat

Form:
__

Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
__

Dilution:
Western Blot 1:3000, Immunohistochemistry 1:3000, Immunohistochemistry-Paraffin 1:3000

Gene Alias:
AQP-7, AQP7L, AQP9MGC149556, AQPapaquaglyceroporin-7, Aquaglyceroporin-7, aquaporin 7, Aquaporin adipose, aquaporin-7, Aquaporin-7-like, MGC149555

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Isotype:
__