NB005593
NKX2.2 Antibody (NX2/294), FITC, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB005593-Each-of-1 | In Stock | ₹ 55,271.76 |
NB005593 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
NKX2.2
Classification
Monoclonal
Conjugate
FITC
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
NKX2-2
Immunogen
Human full-length recombinant NKX2.2 protein (Uniprot: O95096)
Quantity
0.1 mL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat, Chicken
Isotype
IgG2b κ
Applications
ELISA
Clone
NX2/294
Dilution
ELISA
Gene Alias
Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Test Specificity
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Content And Storage
Store at 4°C in the dark.
Related Products
Description
- NKX2.2 Monoclonal specifically detects NKX2.2 in Human, Mouse, Rat, Chicken samples
- It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Compare Similar Items
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Antigen: NKX2.2
Classification: Monoclonal
Conjugate: FITC
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: NKX2-2
Immunogen: Human full-length recombinant NKX2.2 protein (Uniprot: O95096)
Quantity: 0.1 mL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Chicken
Isotype: IgG2b κ
Applications: ELISA
Clone: NX2/294
Dilution: ELISA
Gene Alias: Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Content And Storage: Store at 4°C in the dark.
Antigen:
NKX2.2
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
NKX2-2
Immunogen:
Human full-length recombinant NKX2.2 protein (Uniprot: O95096)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat, Chicken
Isotype:
IgG2b κ
Applications:
ELISA
Clone:
NX2/294
Dilution:
ELISA
Gene Alias:
Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Content And Storage:
Store at 4°C in the dark.
Antigen: Vimentin
Classification: Monoclonal
Conjugate: FITC
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: VIM
Immunogen: Recombinant full-length human vimentin protein (Uniprot: P08670)
Quantity: 0.1 mL
Primary or Secondary: Primary
Target Species: Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse (Negative), Rat (Negative)
Isotype: IgG1 κ
Applications: ELISA, Immunoassay
Clone: VM452
Dilution: ELISA, Knockout Validated
Gene Alias: FLJ36605, vimentin
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: This monoclonal antibody reacts with a 58kDa protein identified as Vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of Vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-Vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-Vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain Vimentin, e.g. hepatoma and seminoma. Anti-Vimentin is also useful as a tissue process control reagent.
Content And Storage: Store at 4°C in the dark.
Antigen:
Vimentin
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
VIM
Immunogen:
Recombinant full-length human vimentin protein (Uniprot: P08670)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Target Species:
Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse (Negative), Rat (Negative)
Isotype:
IgG1 κ
Applications:
ELISA, Immunoassay
Clone:
VM452
Dilution:
ELISA, Knockout Validated
Gene Alias:
FLJ36605, vimentin
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
This monoclonal antibody reacts with a 58kDa protein identified as Vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of Vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-Vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-Vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain Vimentin, e.g. hepatoma and seminoma. Anti-Vimentin is also useful as a tissue process control reagent.
Content And Storage:
Store at 4°C in the dark.
Antigen: NF-H
Classification: Monoclonal
Conjugate: FITC
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: NEFH
Immunogen: Triton-X 100 insoluble protein fraction of rat brain (Uniprot: P12036)
Quantity: 0.1 mL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Porcine, Chicken
Isotype: IgG1 κ
Applications: ELISA
Clone: RT97
Dilution: ELISA
Gene Alias: 200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: This monoclonal antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Content And Storage: Store at 4°C in the dark.
Antigen:
NF-H
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
NEFH
Immunogen:
Triton-X 100 insoluble protein fraction of rat brain (Uniprot: P12036)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat, Porcine, Chicken
Isotype:
IgG1 κ
Applications:
ELISA
Clone:
RT97
Dilution:
ELISA
Gene Alias:
200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
This monoclonal antibody reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Content And Storage:
Store at 4°C in the dark.
Antigen: ErbB2/Her2
Classification: Monoclonal
Conjugate: DyLight 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: ERBB2
Immunogen: Recombinant human ErbB2/Her2 protein (Uniprot: IDP04626)
Quantity: 0.1 mL
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: HRB2/451
Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Cell Surface)
Gene Alias: CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Test Specificity: This monoclonal antibody is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Content And Storage: Store at 4°C in the dark.
Antigen:
ErbB2/Her2
Classification:
Monoclonal
Conjugate:
DyLight 594
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
ERBB2
Immunogen:
Recombinant human ErbB2/Her2 protein (Uniprot: IDP04626)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
HRB2/451
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Flow (Cell Surface)
Gene Alias:
CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Test Specificity:
This monoclonal antibody is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Content And Storage:
Store at 4°C in the dark.