RB1 Antibody (1F8), DyLight 594, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB008292-Each-of-1 | In Stock | ₹ 56,298.48 |
NB008292 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,298.48
GST (18%): ₹ 10,133.726
Total Price: ₹ 66,432.206
Antigen
RB1
Classification
Monoclonal
Conjugate
DyLight 594
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
RB1
Immunogen
Recombinant human RB1 protein fragment of 283 amino acid residues. (Uniprot: P06400)
Quantity
0.1 mL
Research Discipline
Cancer, Cell Cycle and Replication, Phospho Specific, Transcription Factors and Regulators, Tumor Suppressors
Test Specificity
Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
Content And Storage
Store at 4°C in the dark.
Applications
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone
1F8
Dilution
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias
OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse
Isotype
IgG1 κ
Related Products
Description
- RB1 Monoclonal specifically detects RB1 in Human, Mouse samples
- It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: RB1
Classification: Monoclonal
Conjugate: DyLight 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: RB1
Immunogen: Recombinant human RB1 protein fragment of 283 amino acid residues. (Uniprot: P06400)
Quantity: 0.1 mL
Research Discipline: Cancer, Cell Cycle and Replication, Phospho Specific, Transcription Factors and Regulators, Tumor Suppressors
Test Specificity: Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: 1F8
Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Isotype: IgG1 κ
Antigen: DOG1/TMEM16A
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: ANO1
Immunogen: Recombinant human canine1/TMEM16A protein fragment (around aa 2-101) (exact sequence is proprietary) (Uniprot: Q5XX6)
Quantity: 0.1 mL
Research Discipline: __
Test Specificity: __
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: DG1/1485
Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: ANO1, anoctamin 1, DOG1, ORAOV2, TAOS2, TMEM16A
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG2b κ
Antigen: PAX8
Classification: Monoclonal
Conjugate: DyLight 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: PAX8
Immunogen: Recombinant fragment (around aa 60-261) of human PAX8 protein (exact sequence is proprietary) (Uniprot: Q06710)
Quantity: 0.1 mL
Research Discipline: Cancer
Test Specificity: Recognizes a protein of 62kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: PAX8/1491
Dilution: Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: paired box 8, paired box gene 8, paired box protein Pax-8, paired domain gene 8
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG2b κ