NB005644

ER alpha/NR3A1 Antibody (ER505), FITC, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB005644-Each-of-1 In Stock ₹ 53,688.90

NB005644 - Each of 1

₹ 53,688.90

In Stock

Quantity

1

Base Price: ₹ 53,688.90

GST (18%): ₹ 9,664.002

Total Price: ₹ 63,352.902

Antigen

ER alpha/NR3A1

Classification

Monoclonal

Conjugate

FITC

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

ESR1

Immunogen

Recombinant human ER alpha/NR3A1 alpha protein (aa2-185) (Uniprot: P03372)

Quantity

0.1 mL

Research Discipline

Angiogenesis, Breast Cancer, Cancer, Cell Biology, Cell Cycle and Replication, Dendritic Cell Markers, GPCR, Neuroscience, Phospho Specific, Signal Transduction, Transcription Factors and Regulators

Test Specificity

This monoclonal antibody is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This monoclonal antibody is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

ER505

Dilution

Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias

ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG1 κ

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Description

  • ER alpha/NR3A1 Monoclonal specifically detects ER alpha/NR3A1 in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Intracellular).

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Img

Novus Biologicals

NB005644

--


Antigen:
ER alpha/NR3A1

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
ESR1

Immunogen:
Recombinant human ER alpha/NR3A1 alpha protein (aa2-185) (Uniprot: P03372)

Quantity:
0.1 mL

Research Discipline:
Angiogenesis, Breast Cancer, Cancer, Cell Biology, Cell Cycle and Replication, Dendritic Cell Markers, GPCR, Neuroscience, Phospho Specific, Signal Transduction, Transcription Factors and Regulators

Test Specificity:
This monoclonal antibody is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This monoclonal antibody is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
ER505

Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NB005645

--


Antigen:
Podocalyxin Like

Classification:
Monoclonal

Conjugate:
DyLight 594

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
PODXL

Immunogen:
A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human Podocalyxin Like (Uniprot: O00592)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Stem Cell Markers

Test Specificity:
Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
3D3

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Rabbit

Isotype:
IgG1 κ

Img

Novus Biologicals

NB005646

--


Antigen:
Podocalyxin Like

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
PODXL

Immunogen:
A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human Podocalyxin Like (Uniprot: O00592)

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Stem Cell Markers

Test Specificity:
Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
3D3

Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Rabbit

Isotype:
IgG1 κ

Img

Novus Biologicals

NB005662

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Antigen:
beta-Catenin

Classification:
Polyclonal

Conjugate:
Alexa Fluor 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
CTNNB1

Immunogen:
A synthetic peptide from the middle of beta-Catenin protein

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology, Cellular Markers, Extracellular Matrix, Immune System Diseases, Mucosal Immunology, Neuroscience, Phospho Specific, Signal Transduction, Stem Cell Signaling Pathway, Wnt Signaling Pathway

Test Specificity:
Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex. In breast ductal neoplasia, beta-catenin is usually localized in cellular membranes. However, in lobular neoplasia, a marked redistribution of beta-catenin throughout the cytoplasm results in a diffuse cytoplasmic pattern. Immuno-staining of beta-catenin and E-cadherin is helps in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Additionally, some rectal and gastric adenocarcinomas demonstrate diffuse cytoplasmic beta-catenin staining and a lack of membranous staining, mimicking the staining pattern observed with lobular breast carcinomas.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
__

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
beta 1 (88kD), beta-catenin, catenin (cadherin-associated protein), beta 1, 88kDa, catenin beta-1, CTNNB, DKFZp686D02253, FLJ25606, FLJ37923

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Isotype:
IgG