NB005677

Uroplakin III, Rabbit anti-Human, Janelia Fluor 646, Polyclonal, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NB005677-Each-of-1 In Stock ₹ 52,277.16

NB005677 - Each of 1

₹ 52,277.16

In Stock

Quantity

1

Base Price: ₹ 52,277.16

GST (18%): ₹ 9,409.889

Total Price: ₹ 61,687.049

Antigen

Uroplakin III

Classification

Polyclonal

Dilution

Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence

Gene Alias

MGC119178, UP3a, UPIII, UPIIIA, UPK3, UPK3A, uroplakin 3, uroplakin 3A, Uroplakin III, uroplakin3a, uroplakin-3a

Host Species

Rabbit

Purification Method

Protein A purified

Regulatory Status

RUO

Test Specificity

Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence

Conjugate

Janelia Fluor 646

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

UPK3A

Immunogen

A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

Quantity

0.1 mL

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG

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Description

  • Uroplakin III Polyclonal specifically detects Uroplakin III in Human samples
  • It is validated for Western Blot.

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Novus Biologicals

NB005677

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Antigen:
Uroplakin III

Classification:
Polyclonal

Dilution:
Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence

Gene Alias:
MGC119178, UP3a, UPIII, UPIIIA, UPK3, UPK3A, uroplakin 3, uroplakin 3A, Uroplakin III, uroplakin3a, uroplakin-3a

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Test Specificity:
Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence

Conjugate:
Janelia Fluor 646

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
UPK3A

Immunogen:
A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

Quantity:
0.1 mL

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG

Img

Novus Biologicals

NB005680

--


Antigen:
UCH-L1/PGP9.5

Classification:
Monoclonal

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Test Specificity:
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Conjugate:
DyLight 594

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
UCHL1

Immunogen:
UCH-L1/PGP9.5 protein from brain (Uniprot: P09936)

Quantity:
0.1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Porcine, Bovine, Zebrafish

Isotype:
IgG1 κ

Img

Novus Biologicals

NB005682

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Antigen:
NCAM-1/CD56

Classification:
Monoclonal

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
CD56, CD56/ NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, NCAMantigen recognized by monoclonal 5.1H11, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Test Specificity:
This monoclonal antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Conjugate:
DyLight 594

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
NCAM1

Immunogen:
Membrane preparation of a small cell lung carcinoma.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Target Species:
Human, Rat, Zebrafish

Isotype:
IgG1 κ

Img

Novus Biologicals

NB005683

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Antigen:
Cytokeratin 19

Classification:
Monoclonal

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
40-kDa keratin intermediate filament, CK19, CK-19, cytokeratin 19, K19, K1CS, keratin 19, keratin, type I cytoskeletal 19, keratin, type I, 40-kd, Keratin-19, MGC15366

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Test Specificity:
This monoclonal antibody reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. Its epitope maps between amino acid 312-335. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Conjugate:
DyLight 594

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
KRT19

Immunogen:
Human breast cancer MCF-7 cells were used as the immunogen for the Keratin-19 antibody.

Quantity:
0.1 mL

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2a λ