NB005947
Cytokeratin 8 Antibody (SPM538), Alexa Fluor™ 594, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB005947-Each-of-1 | In Stock | ₹ 55,271.76 |
NB005947 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Cytokeratin 8
Classification
Monoclonal
Conjugate
Alexa Fluor 594
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols
KRT8
Immunogen
Cytoskeleton preparation containing cytokeratin 8 (Uniprot: P05787)
Quantity
0.1 mL
Research Discipline
Cancer, Cell Biology, Cellular Markers, Phospho Specific
Test Specificity
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ('ring-like, perinuclear') from ductal ('peripheral-predominant') carcinoma of the breast.
Content And Storage
Store at 4°C in the dark.
Applications
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone
SPM538
Dilution
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias
CARD2, CK8, CK-8, CYK8, Cytokeratin-8, K2C8, K8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Rat, Zebrafish
Isotype
IgG1 κ
Related Products
Description
- Cytokeratin 8 Monoclonal specifically detects Cytokeratin 8 in Human, Rat, Zebrafish samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
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Antigen: Cytokeratin 8
Classification: Monoclonal
Conjugate: Alexa Fluor 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: KRT8
Immunogen: Cytoskeleton preparation containing cytokeratin 8 (Uniprot: P05787)
Quantity: 0.1 mL
Research Discipline: Cancer, Cell Biology, Cellular Markers, Phospho Specific
Test Specificity: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ('ring-like, perinuclear') from ductal ('peripheral-predominant') carcinoma of the breast.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM538
Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: CARD2, CK8, CK-8, CYK8, Cytokeratin-8, K2C8, K8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Rat, Zebrafish
Isotype: IgG1 κ
Antigen:
Cytokeratin 8
Classification:
Monoclonal
Conjugate:
Alexa Fluor 594
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
KRT8
Immunogen:
Cytoskeleton preparation containing cytokeratin 8 (Uniprot: P05787)
Quantity:
0.1 mL
Research Discipline:
Cancer, Cell Biology, Cellular Markers, Phospho Specific
Test Specificity:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ('ring-like, perinuclear') from ductal ('peripheral-predominant') carcinoma of the breast.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
SPM538
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
CARD2, CK8, CK-8, CYK8, Cytokeratin-8, K2C8, K8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Rat, Zebrafish
Isotype:
IgG1 κ
Antigen: Cytokeratin 8
Classification: Monoclonal
Conjugate: FITC
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: KRT8
Immunogen: Cytoskeleton preparation containing cytokeratin 8 (Uniprot: P05787)
Quantity: 0.1 mL
Research Discipline: Cancer, Cell Biology, Cellular Markers, Phospho Specific
Test Specificity: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ('ring-like, perinuclear') from ductal ('peripheral-predominant') carcinoma of the breast.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPM538
Dilution: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: CARD2, CK8, CK-8, CYK8, Cytokeratin-8, K2C8, K8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Rat, Zebrafish
Isotype: IgG1 κ
Antigen:
Cytokeratin 8
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
KRT8
Immunogen:
Cytoskeleton preparation containing cytokeratin 8 (Uniprot: P05787)
Quantity:
0.1 mL
Research Discipline:
Cancer, Cell Biology, Cellular Markers, Phospho Specific
Test Specificity:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ('ring-like, perinuclear') from ductal ('peripheral-predominant') carcinoma of the breast.
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
SPM538
Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
CARD2, CK8, CK-8, CYK8, Cytokeratin-8, K2C8, K8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Rat, Zebrafish
Isotype:
IgG1 κ
Antigen: TGF-alpha
Classification: Monoclonal
Conjugate: Alexa Fluor 350
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: TGFA
Immunogen: A 10-amino acid synthetic peptide (aa34-43; PPVAAAVVSH) from human TGF-alpha (Uniprot: P01135)
Quantity: 0.1 mL
Research Discipline: Angiogenesis, Cell Cycle and Replication, Signal Transduction
Test Specificity: This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this monoclonal antibody is completely blocked by the peptide used for raising this antibody. TGF (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: SPM542
Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: protransforming growth factor alpha, TFGA, transforming growth factor, alpha, transforming growth factor-alpha
Host Species: Mouse
Purification Method: Protein L or PEG purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Rabbit, Zebrafish
Isotype: IgM κ
Antigen:
TGF-alpha
Classification:
Monoclonal
Conjugate:
Alexa Fluor 350
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
TGFA
Immunogen:
A 10-amino acid synthetic peptide (aa34-43; PPVAAAVVSH) from human TGF-alpha (Uniprot: P01135)
Quantity:
0.1 mL
Research Discipline:
Angiogenesis, Cell Cycle and Replication, Signal Transduction
Test Specificity:
This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this monoclonal antibody is completely blocked by the peptide used for raising this antibody. TGF (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
SPM542
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
protransforming growth factor alpha, TFGA, transforming growth factor, alpha, transforming growth factor-alpha
Host Species:
Mouse
Purification Method:
Protein L or PEG purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Rabbit, Zebrafish
Isotype:
IgM κ
Antigen: TGF-alpha
Classification: Monoclonal
Conjugate: Alexa Fluor 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: TGFA
Immunogen: A 10-amino acid synthetic peptide (aa34-43; PPVAAAVVSH) from human TGF-alpha (Uniprot: P01135)
Quantity: 0.1 mL
Research Discipline: Angiogenesis, Cell Cycle and Replication, Signal Transduction
Test Specificity: This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this monoclonal antibody is completely blocked by the peptide used for raising this antibody. TGF (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: SPM542
Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias: protransforming growth factor alpha, TFGA, transforming growth factor, alpha, transforming growth factor-alpha
Host Species: Mouse
Purification Method: Protein L or PEG purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Rabbit, Zebrafish
Isotype: IgM κ
Antigen:
TGF-alpha
Classification:
Monoclonal
Conjugate:
Alexa Fluor 594
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
TGFA
Immunogen:
A 10-amino acid synthetic peptide (aa34-43; PPVAAAVVSH) from human TGF-alpha (Uniprot: P01135)
Quantity:
0.1 mL
Research Discipline:
Angiogenesis, Cell Cycle and Replication, Signal Transduction
Test Specificity:
This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this monoclonal antibody is completely blocked by the peptide used for raising this antibody. TGF (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
SPM542
Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias:
protransforming growth factor alpha, TFGA, transforming growth factor, alpha, transforming growth factor-alpha
Host Species:
Mouse
Purification Method:
Protein L or PEG purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Rabbit, Zebrafish
Isotype:
IgM κ