NB006110

CD2 Antibody (1E7E8.G4), DyLight 594, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB006110-Each-of-1 In Stock ₹ 56,298.48

NB006110 - Each of 1

₹ 56,298.48

In Stock

Quantity

1

Base Price: ₹ 56,298.48

GST (18%): ₹ 10,133.726

Total Price: ₹ 66,432.206

Antigen

CD2

Classification

Monoclonal

Conjugate

DyLight 594

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

CD2

Immunogen

Human Thymocytes/Sezary T cells

Quantity

0.1 mL

Research Discipline

Adaptive Immunity, Apoptosis, Immunology

Test Specificity

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone

1E7E8.G4

Dilution

Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Alias

CD2 antigen, CD2 antigen (p50), sheep red blood cell receptor, CD2 molecule, Erythrocyte receptor, FLJ46032, LFA-2, LFA-3 receptor, lymphocyte-function antigen-2, Rosette receptor, SRBC, T11, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG2a κ

Related Products

Img

Novus Biologicals

NB006093

--

Img

Novus Biologicals

NB006094

--

Img

Novus Biologicals

NB006385

--

Img

Novus Biologicals

NB006737

--

Img

Novus Biologicals

NB006736

--

Img

Novus Biologicals

NB006738

--

Img

Novus Biologicals

NB006177

--

Img

Novus Biologicals

NB006179

--

Description

  • CD2 Monoclonal specifically detects CD2 in Human samples
  • It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB006110

--


Antigen:
CD2

Classification:
Monoclonal

Conjugate:
DyLight 594

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
CD2

Immunogen:
Human Thymocytes/Sezary T cells

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Apoptosis, Immunology

Test Specificity:
CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)

Clone:
1E7E8.G4

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen

Gene Alias:
CD2 antigen, CD2 antigen (p50), sheep red blood cell receptor, CD2 molecule, Erythrocyte receptor, FLJ46032, LFA-2, LFA-3 receptor, lymphocyte-function antigen-2, Rosette receptor, SRBC, T11, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2a κ

Img

Novus Biologicals

NB006113

--


Antigen:
Thyroglobulin

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
TG

Immunogen:
Human thyroid follicular cells

Quantity:
0.1 mL

Research Discipline:
Cancer, Cell Biology

Test Specificity:
Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
2H11 + 6E1

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
AITD3TGN, TDH3, Tg, thyroglobulin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

NB006115

--


Antigen:
EpCAM/TROP1

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
EPCAM

Immunogen:
MCF-7 human breast cancer cells

Quantity:
0.1 mL

Research Discipline:
Cancer, Cancer Stem Cells, Tumor Biomarkers

Test Specificity:
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
323/A3

Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Rat (Negative)

Isotype:
IgG1 κ

Img

Novus Biologicals

NB006117

--


Antigen:
Golgi Complex

Classification:
Monoclonal

Conjugate:
Alexa Fluor 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
__

Immunogen:
SU-DHL-1 large cell lymphoma cells.

Quantity:
0.1 mL

Research Discipline:
__

Test Specificity:
This monoclonal antibody recognizes an antigen associated with the Golgi complex in human cells only. It can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This monoclonal antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae.

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
371-4

Dilution:
Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
__

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse (Negative), Rat (Negative)

Isotype:
IgG1 κ