NB007501

Myosin heavy chain 11 Antibody (MYH11/923 + SMMS-1), DyLight 350, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB007501-Each-of-1 In Stock ₹ 55,271.76

NB007501 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Myosin heavy chain 11

Classification

Monoclonal

Conjugate

DyLight 350

Formulation

50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols

MYH11

Immunogen

Recombinant human Myosin heavy chain 11 protein (Myosin heavy chain 11/923); Human uterus extract (SMMS-1) (Uniprot: P35749)

Quantity

0.1 mL

Research Discipline

Hypoxia, Stem Cell Markers

Test Specificity

Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Content And Storage

Store at 4°C in the dark.

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone

MYH11/923 + SMMS-1

Dilution

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias

AAT4, FAA4, MYH11, MYH11 myosin, heavy chain 11, smooth muscle, SMHC, SMMHC, Smooth muscle myosin heavy chain

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Rat

Isotype

IgG1 κ

Related Products

Img

Novus Biologicals

NB007500

--

Img

Novus Biologicals

NB007493

--

Img

Novus Biologicals

NB007486

--

Img

Novus Biologicals

NB007489

--

Img

Novus Biologicals

NB007487

--

Img

Novus Biologicals

NB007491

--

Img

Novus Biologicals

NB007496

--

Img

Novus Biologicals

NB007499

--

Description

  • Myosin heavy chain 11 Monoclonal specifically detects Myosin heavy chain 11 in Human, Rat samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB007501

--


Antigen:
Myosin heavy chain 11

Classification:
Monoclonal

Conjugate:
DyLight 350

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
MYH11

Immunogen:
Recombinant human Myosin heavy chain 11 protein (Myosin heavy chain 11/923); Human uterus extract (SMMS-1) (Uniprot: P35749)

Quantity:
0.1 mL

Research Discipline:
Hypoxia, Stem Cell Markers

Test Specificity:
Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
MYH11/923 + SMMS-1

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
AAT4, FAA4, MYH11, MYH11 myosin, heavy chain 11, smooth muscle, SMHC, SMMHC, Smooth muscle myosin heavy chain

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

NB007503

--


Antigen:
CPS1

Classification:
Monoclonal

Conjugate:
DyLight 594

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
CPS1

Immunogen:
Recombinant human CPS1 protein (Uniprot: P31327)

Quantity:
0.1 mL

Research Discipline:
__

Test Specificity:
This MAb recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.

Content And Storage:
Store at 4°C in the dark.

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
SPM615

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
carbamoyl-phosphate synthase [ammonia], mitochondrial, carbamoyl-phosphate synthase 1, mitochondrial, carbamoyl-phosphate synthetase 1, mitochondrial, carbamoylphosphate synthetase I, Carbamoyl-phosphate synthetase I, CPSase I, CPSASE1, EC 6.3.4.16

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Canine

Isotype:
IgG1 κ

Img

Novus Biologicals

NB007505

--


Antigen:
CD34

Classification:
Monoclonal

Conjugate:
Alexa Fluor 405

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
CD34

Immunogen:
Detergent solubilized vesicular suspension prepared from human term placenta (QBEnd/10); Recombinant full-length human CD34 protein (CD34/763) (Uniprot: P28906)

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Test Specificity:
This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
QBEnd/10 + HPCA1/763

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 λ

Img

Novus Biologicals

NB007506

--


Antigen:
CD34

Classification:
Monoclonal

Conjugate:
Alexa Fluor 488

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
CD34

Immunogen:
Detergent solubilized vesicular suspension prepared from human term placenta (QBEnd/10); Recombinant full-length human CD34 protein (CD34/763) (Uniprot: P28906)

Quantity:
0.1 mL

Research Discipline:
Adaptive Immunity, Angiogenesis, B Cell Development and Differentiation Markers, Breast Cancer, Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, Hypoxia, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Myeloid Cell Markers, Myeloid derived Suppressor Cell, Neuronal Cell Markers, Neuroscience, Stem Cell Markers, Tumor Suppressors

Test Specificity:
This monoclonal antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposis sarcoma, but with a lower specificity.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone:
QBEnd/10 + HPCA1/763

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence

Gene Alias:
CD34 antigenhematopoietic progenitor cell antigen CD34, CD34 molecule

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG1 λ