Manufacturer: Novus Biologicals
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NB009172-Each-of-1 | In Stock | ₹ 55,271.76 |
NB009172 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
TRACP/PAP/ACP5
Monoclonal
DyLight 755
50mM Sodium Borate with 0.05% Sodium Azide
ACP5
Recombinant full-length human TRACP/PAP/ACP5 protein (Uniprot: P13686)
0.1 mL
Protein Phosphatase
It recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This monoclonal antibody reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis.Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gauchers Disease, HIV-induc
Store at 4°C in the dark.
Immunohistochemistry, Immunohistochemistry (Paraffin)
rACP5/1070
Immunohistochemistry, Immunohistochemistry-Paraffin
HPAP, TRACP5a, TRACP5b, TRAP, TrATPase
Mouse
Protein A or G purified
RUO
Primary
Human, Mouse, Rat
IgG1 κ