NB011612

NPM1 Antibody (NPM1/3287), Biotin, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB011612-Each-of-1 In Stock ₹ 55,271.76

NB011612 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

NPM1

Classification

Monoclonal

Conjugate

Biotin

Formulation

PBS with 0.05% Sodium Azide

Gene Symbols

NPM1

Immunogen

Recombinant fragment (around aa185-287) of human NPM1 protein (exact sequence is proprietary) (Uniprot: P06748 )

Quantity

0.1 mL

Research Discipline

Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors

Test Specificity

Recognizes a 33kDa glycoprotein, identified as NPM1 (NPM). It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone

NPM1/3287

Dilution

Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias

B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Isotype

IgG2b κ

Related Products

Img

Novus Biologicals

NB011565

--

Img

Novus Biologicals

NB011613

--

Img

Novus Biologicals

NB011614

--

Img

Novus Biologicals

NB011616

--

Img

Novus Biologicals

NB011619

--

Img

Novus Biologicals

NB011623

--

Img

Novus Biologicals

NB011624

--

Img

Novus Biologicals

NB011618

--

Description

  • NPM1 Monoclonal specifically detects NPM1 in Human samples
  • It is validated for Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB011612

--


Antigen:
NPM1

Classification:
Monoclonal

Conjugate:
Biotin

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
NPM1

Immunogen:
Recombinant fragment (around aa185-287) of human NPM1 protein (exact sequence is proprietary) (Uniprot: P06748 )

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors

Test Specificity:
Recognizes a 33kDa glycoprotein, identified as NPM1 (NPM). It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
NPM1/3287

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NB011613

--


Antigen:
NPM1

Classification:
Monoclonal

Conjugate:
DyLight 650

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
NPM1

Immunogen:
Recombinant fragment (around aa185-287) of human NPM1 protein (exact sequence is proprietary) (Uniprot: P06748 )

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors

Test Specificity:
Recognizes a 33kDa glycoprotein, identified as NPM1 (NPM). It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
NPM1/3287

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NB011614

--


Antigen:
NPM1

Classification:
Monoclonal

Conjugate:
DyLight 594

Formulation:
50mM Sodium Borate with 0.05% Sodium Azide

Gene Symbols:
NPM1

Immunogen:
Recombinant fragment (around aa185-287) of human NPM1 protein (exact sequence is proprietary) (Uniprot: P06748 )

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors

Test Specificity:
Recognizes a 33kDa glycoprotein, identified as NPM1 (NPM). It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
NPM1/3287

Dilution:
Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ

Img

Novus Biologicals

NB011615

--


Antigen:
NPM1

Classification:
Monoclonal

Conjugate:
FITC

Formulation:
PBS with 0.05% Sodium Azide

Gene Symbols:
NPM1

Immunogen:
Recombinant fragment (around aa185-287) of human NPM1 protein (exact sequence is proprietary) (Uniprot: P06748 )

Quantity:
0.1 mL

Research Discipline:
Apoptosis, Cancer, Cell Cycle and Replication, Chromatin Research, DNA replication Transcription Translation and Splicing, Mitotic Regulators, Phospho Specific, Signal Transduction, Tumor Suppressors

Test Specificity:
Recognizes a 33kDa glycoprotein, identified as NPM1 (NPM). It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.

Content And Storage:
Store at 4°C in the dark.

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
NPM1/3287

Dilution:
ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
B23, MGC104254, NPMnucleophosmin/nucleoplasmin family, member 1, Nucleolar phosphoprotein B23, Nucleolar protein NO38, nucleophosmin, nucleophosmin (nucleolar phosphoprotein B23, numatrin), numatrin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Isotype:
IgG2b κ