NB015764

Integrin beta 7 Antibody (FIB27), DyLight 550, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NB015764-Each-of-1 In Stock ₹ 55,271.76

NB015764 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

Integrin beta 7

Classification

Monoclonal

Conjugate

DyLight 550

Formulation

50mM Sodium Borate

Gene Symbols

ITGB7

Immunogen

FIB27 was prepared by immunizing rats with TK1 cells.

Quantity

0.1 mL

Research Discipline

Signal Transduction

Gene ID (Entrez)

3695

Target Species

Human, Mouse

Form

Purified

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence

Clone

FIB27

Dilution

Flow Cytometry, Immunocytochemistry/Immunofluorescence

Gene Alias

Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7

Host Species

Rabbit

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

FIB27 binds specifically to both human and mouse Integrin beta 7 at epitope region Dl on which is involved in all a4b7-mediated adhesion events. Does not compete with DAKT32 for binding. FIB27 blocks LS722-induced TK1 cell aggregation (mAb LS722 is an activating anti-a4B7 antibody and induces aggregation via an a4B7-dependent pathway). Integrin beta 7 is one subunit is a heterodimer which makes up an intergin molecule. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.

Content And Storage

Store at 4°C in the dark.

Isotype

IgG κ

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Description

  • Integrin beta 7 Monoclonal specifically detects Integrin beta 7 in Human, Mouse samples
  • It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NB015764

--


Antigen:
Integrin beta 7

Classification:
Monoclonal

Conjugate:
DyLight 550

Formulation:
50mM Sodium Borate

Gene Symbols:
ITGB7

Immunogen:
FIB27 was prepared by immunizing rats with TK1 cells.

Quantity:
0.1 mL

Research Discipline:
Signal Transduction

Gene ID (Entrez):
3695

Target Species:
Human, Mouse

Form:
Purified

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence

Clone:
FIB27

Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence

Gene Alias:
Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
FIB27 binds specifically to both human and mouse Integrin beta 7 at epitope region Dl on which is involved in all a4b7-mediated adhesion events. Does not compete with DAKT32 for binding. FIB27 blocks LS722-induced TK1 cell aggregation (mAb LS722 is an activating anti-a4B7 antibody and induces aggregation via an a4B7-dependent pathway). Integrin beta 7 is one subunit is a heterodimer which makes up an intergin molecule. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG κ

Img

Novus Biologicals

NB015766

--


Antigen:
Integrin beta 7

Classification:
Monoclonal

Conjugate:
DyLight 405

Formulation:
50mM Sodium Borate

Gene Symbols:
ITGB7

Immunogen:
FIB27 was prepared by immunizing rats with TK1 cells.

Quantity:
0.1 mL

Research Discipline:
Signal Transduction

Gene ID (Entrez):
3695

Target Species:
Human, Mouse

Form:
Purified

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence

Clone:
FIB27

Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence

Gene Alias:
Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
FIB27 binds specifically to both human and mouse Integrin beta 7 at epitope region Dl on which is involved in all a4b7-mediated adhesion events. Does not compete with DAKT32 for binding. FIB27 blocks LS722-induced TK1 cell aggregation (mAb LS722 is an activating anti-a4B7 antibody and induces aggregation via an a4B7-dependent pathway). Integrin beta 7 is one subunit is a heterodimer which makes up an intergin molecule. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG κ

Img

Fischer Scientific

NB015767

--


Antigen:
CD44

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS

Gene Symbols:
CD44

Immunogen:
This antibody was produced by immunizing a Fischer rat with human tonsil lymphocytes (10^7cells intraperitoneally in Freund's complete adjuvant). A boost was given 2 weeks later (intravascularly in saline).

Quantity:
0.025 mg

Research Discipline:
Angiogenesis, Apoptosis, Cancer, Cell Biology, Core ESC Like Genes, Extracellular Matrix, Hematopoietic Stem Cell Markers, Immunology, Mesenchymal Stem Cell Markers, Oncogenes, Phospho Specific, Protein Kinase, Signal Transduction, Stem Cell Markers

Gene ID (Entrez):
960

Target Species:
Human, Mouse, Rat, Bovine, Goat, Primate, Rabbit, Sheep

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Blocking Assay

Clone:
Hermes-1

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Block/Neutralize

Gene Alias:
CD44 antigen, CD44 molecule (Indian blood group), CD44R, CDw44, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan sulfate proteoglycan, Hermes antigen, homing function and Indian blood group system, HUTCH-I, Hyaluronate receptor, IN, LHR, MC56, MDU2CD44 antigen (homing function and Indian blood group system), MDU3CDW44, MIC4MGC10468, Pgp1, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antibody is specific for CD44 (gp90 epitope cluster I), which is selectively expressed on normal or transformed lymphoid cells that are able to recognize and bind to high endothelial venules (specialized vessels that mediate lymphocyte exit from the blood into lymphoid organs). Although this antibody was raised against human CD44, it cross-reacts with murine, rat, rabbit, primate, sheep, bovine and goat CD44.

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Isotype:
IgG κ

Img

Fischer Scientific

NB015768

--


Antigen:
CD44

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
PBS

Gene Symbols:
CD44

Immunogen:
This antibody was produced by immunizing a Fischer rat with human tonsil lymphocytes (10^7cells intraperitoneally in Freund's complete adjuvant). A boost was given 2 weeks later (intravascularly in saline).

Quantity:
0.2 mg

Research Discipline:
Angiogenesis, Apoptosis, Cancer, Cell Biology, Core ESC Like Genes, Extracellular Matrix, Hematopoietic Stem Cell Markers, Immunology, Mesenchymal Stem Cell Markers, Oncogenes, Phospho Specific, Protein Kinase, Signal Transduction, Stem Cell Markers

Gene ID (Entrez):
960

Target Species:
Human, Mouse, Rat, Bovine, Goat, Primate, Rabbit, Sheep

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Blocking Assay

Clone:
Hermes-1

Dilution:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Block/Neutralize

Gene Alias:
CD44 antigen, CD44 molecule (Indian blood group), CD44R, CDw44, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan sulfate proteoglycan, Hermes antigen, homing function and Indian blood group system, HUTCH-I, Hyaluronate receptor, IN, LHR, MC56, MDU2CD44 antigen (homing function and Indian blood group system), MDU3CDW44, MIC4MGC10468, Pgp1, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I

Host Species:
Rabbit

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antibody is specific for CD44 (gp90 epitope cluster I), which is selectively expressed on normal or transformed lymphoid cells that are able to recognize and bind to high endothelial venules (specialized vessels that mediate lymphocyte exit from the blood into lymphoid organs). Although this antibody was raised against human CD44, it cross-reacts with murine, rat, rabbit, primate, sheep, bovine and goat CD44.

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Isotype:
IgG κ