NB017705

Siglec-1/CD169 Antibody (ED3) - BSA Free, Novus Biologicals™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 NB017705-Each-of-1 In Stock ₹ 20,833.86

NB017705 - Each of 1

₹ 20,833.86

In Stock

Quantity

1

Base Price: ₹ 20,833.86

GST (18%): ₹ 3,750.095

Total Price: ₹ 24,583.955

Antigen

Siglec-1/CD169

Classification

Monoclonal

Concentration

0.5 mg/mL

Dilution

Flow Cytometry 1:500, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:50-1:250

Gene Alias

CD169, FLJ00051, sialic acid binding Ig-like lectin 1, sialoadhesin, sialoadhesin

Host Species

Mouse

Purification Method

Protein A purified

Regulatory Status

RUO

Gene ID (Entrez)

6614

Target Species

Rat

Form

Purified

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry (Frozen)

Clone

ED3

Conjugate

Unconjugated

Formulation

PBS (pH 7.4) with 0.09% Sodium Azide

Gene Symbols

SIGLEC1

Immunogen

Rat Spleen cell homogenate

Quantity

0.025 mg

Primary or Secondary

Primary

Test Specificity

NB100-65301 recognizes the rat CD169 cell surface antigen, a 185kD molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicious property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid.

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG2a

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Description

  • Siglec-1/CD169 Monoclonal specifically detects Siglec-1/CD169 in Rat samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Frozen.

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Fischer Scientific

NB017705

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Antigen:
Siglec-1/CD169

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Dilution:
Flow Cytometry 1:500, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:50-1:250

Gene Alias:
CD169, FLJ00051, sialic acid binding Ig-like lectin 1, sialoadhesin, sialoadhesin

Host Species:
Mouse

Purification Method:
Protein A purified

Regulatory Status:
RUO

Gene ID (Entrez):
6614

Target Species:
Rat

Form:
Purified

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry (Frozen)

Clone:
ED3

Conjugate:
Unconjugated

Formulation:
PBS (pH 7.4) with 0.09% Sodium Azide

Gene Symbols:
SIGLEC1

Immunogen:
Rat Spleen cell homogenate

Quantity:
0.025 mg

Primary or Secondary:
Primary

Test Specificity:
NB100-65301 recognizes the rat CD169 cell surface antigen, a 185kD molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicious property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2a

Img

Fischer Scientific

NB017706

--


Antigen:
CD1b

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry 1:25-1:50, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
CD1, CD1A, CD1b antigen, CD1B antigen, b polypeptide, CD1b molecule, cortical thymocyte antigen CD1B, differentiation antigen CD1-alpha-3, MGC125990, MGC125991, R1, T-cell surface glycoprotein CD1b

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
910

Target Species:
Sheep, Equine, Goat, Bovine, Canine

Form:
Purified

Applications:
Immunohistochemistry, Flow Cytometry, Immunoprecipitation, Immunohistochemistry (Frozen)

Clone:
CC20

Conjugate:
Unconjugated

Formulation:
Phosphate Buffered Saline with 0.09% Sodium Azide

Gene Symbols:
CD1B

Immunogen:
Made to Bovine CD1w2

Quantity:
0.025 mg

Primary or Secondary:
Primary

Test Specificity:
Recognizes the bovine CD1w2 cell surface antigen, a glycoprotein heterodimer of 12kD and 46kD. CD1w2 is expressed by cortical thymocytes and a minority of medullary thymocytes, with a pattern similar to antibodies of the CD1b cluster in humans.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2a

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NB017709

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Antigen:
PD-L2/B7-DC/PDCD1LG2

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry 1:100-1:200, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, CD273 antigen, CD273PD-1 ligand 2, MGC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2

Host Species:
Rat

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
80380

Target Species:
Mouse

Form:
Purified

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry, Immunoprecipitation, Flow Cytometry

Clone:
TY25

Conjugate:
Unconjugated

Formulation:
PBS (pH 7.4) with 0.09% Sodium Azide

Gene Symbols:
PDCD1LG2

Immunogen:
B7-DC transfected RAW264.7 cells.

Quantity:
0.025 mg

Primary or Secondary:
Primary

Test Specificity:
NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2a

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Fischer Scientific

NB017710

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Antigen:
CD31/PECAM-1

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry 1:50-1:100, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA', PECA1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet/endothelial cell adhesion molecule

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
5175

Target Species:
Human, Porcine

Form:
Purified

Applications:
Immunofluorescence, Immunohistochemistry, Immunocytochemistry, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
LCI-4

Conjugate:
Unconjugated

Formulation:
Phosphate buffered saline with 0.09% Sodium Azide

Gene Symbols:
PECAM1

Immunogen:
Porcine CD31/human IgGFc fusion protein

Quantity:
0.025 mg

Primary or Secondary:
Primary

Test Specificity:
Recognizes porcine CD31, also known as Platelet endothelial cell adhesion molecule (PECAM-1).

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1