NB017709

PD-L2/B7-DC/PDCD1LG2 Antibody (TY25) - BSA Free, Novus Biologicals™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 NB017709-Each-of-1 In Stock ₹ 17,454.24

NB017709 - Each of 1

₹ 17,454.24

In Stock

Quantity

1

Base Price: ₹ 17,454.24

GST (18%): ₹ 3,141.763

Total Price: ₹ 20,596.003

Antigen

PD-L2/B7-DC/PDCD1LG2

Classification

Monoclonal

Concentration

1.0 mg/mL

Dilution

Flow Cytometry 1:100-1:200, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias

B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, CD273 antigen, CD273PD-1 ligand 2, MGC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2

Host Species

Rat

Purification Method

Protein G purified

Regulatory Status

RUO

Gene ID (Entrez)

80380

Target Species

Mouse

Form

Purified

Applications

Immunohistochemistry (Frozen), Immunohistochemistry, Immunoprecipitation, Flow Cytometry

Clone

TY25

Conjugate

Unconjugated

Formulation

PBS (pH 7.4) with 0.09% Sodium Azide

Gene Symbols

PDCD1LG2

Immunogen

B7-DC transfected RAW264.7 cells.

Quantity

0.025 mg

Primary or Secondary

Primary

Test Specificity

NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG2a

Related Products

Img

Fischer Scientific

NB017735

--

Img

Fischer Scientific

NB017706

--

Img

Fischer Scientific

NB017637

--

Img

Fischer Scientific

NB017703

--

Img

Fischer Scientific

NB017657

--

Img

Fischer Scientific

NB017705

--

Img

Fischer Scientific

NB017723

--

Img

Fischer Scientific

NB017718

--

Description

  • PD-L2/B7-DC/PDCD1LG2 Monoclonal specifically detects PD-L2/B7-DC/PDCD1LG2 in Mouse samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Frozen.

Compare Similar Items

Show Difference

Img

Fischer Scientific

NB017709

--


Antigen:
PD-L2/B7-DC/PDCD1LG2

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry 1:100-1:200, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, CD273 antigen, CD273PD-1 ligand 2, MGC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2

Host Species:
Rat

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
80380

Target Species:
Mouse

Form:
Purified

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry, Immunoprecipitation, Flow Cytometry

Clone:
TY25

Conjugate:
Unconjugated

Formulation:
PBS (pH 7.4) with 0.09% Sodium Azide

Gene Symbols:
PDCD1LG2

Immunogen:
B7-DC transfected RAW264.7 cells.

Quantity:
0.025 mg

Primary or Secondary:
Primary

Test Specificity:
NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2a

Img

Fischer Scientific

NB017710

--


Antigen:
CD31/PECAM-1

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry 1:50-1:100, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA', PECA1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet/endothelial cell adhesion molecule

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
5175

Target Species:
Human, Porcine

Form:
Purified

Applications:
Immunofluorescence, Immunohistochemistry, Immunocytochemistry, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone:
LCI-4

Conjugate:
Unconjugated

Formulation:
Phosphate buffered saline with 0.09% Sodium Azide

Gene Symbols:
PECAM1

Immunogen:
Porcine CD31/human IgGFc fusion protein

Quantity:
0.025 mg

Primary or Secondary:
Primary

Test Specificity:
Recognizes porcine CD31, also known as Platelet endothelial cell adhesion molecule (PECAM-1).

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1

Img

Fischer Scientific

NB017717

--


Antigen:
L-Selectin/CD62L

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry 1:50-1:100, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
6402

Target Species:
Bovine, Human, Primate, Canine

Form:
Purified

Applications:
Immunohistochemistry (Frozen), Immunoprecipitation, Immunohistochemistry, Flow Cytometry

Clone:
FMC46

Conjugate:
Unconjugated

Formulation:
Phosphate buffered saline with 0.09% Sodium Azide

Gene Symbols:
SELL

Immunogen:
PHA stimulated lymphoblasts.

Quantity:
0.025 mg

Primary or Secondary:
Primary

Test Specificity:
NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG2b

Img

Fischer Scientific

NB017718

--


Antigen:
P-Selectin/CD62P

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Dilution:
Flow Cytometry 1:50-1:100, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500

Gene Alias:
CD62P antigen, FLJ45155, PADGEMantigen CD62), selectin P (granule membrane protein 140kDa, antigen CD62)

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
6403

Target Species:
Goat, Human, Sheep, Rat

Form:
Purified

Applications:
Immunoprecipitation, Immunohistochemistry, Immunohistochemistry (Frozen), Flow Cytometry

Clone:
Psel.KO.2.12

Conjugate:
Unconjugated

Formulation:
PBS (pH 7.4) with 0.09% Sodium Azide

Gene Symbols:
SELP

Immunogen:
P-Selectin transfected 300.19 cells.

Quantity:
0.025 mg

Primary or Secondary:
Primary

Test Specificity:
NB100-65391 recognizes the P-Selectin cell surface antigen, a 140kD glycoprotein. P-Selectin is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. Clone Psel.KO.2.12 is reported to inhibit P-selectin-dependent adhesion between HL60 cells and P-selectin transfected COS cells.

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype:
IgG1