L-Selectin/CD62L Antibody (FMC46) - BSA Free, Novus Biologicals™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB017717-Each-of-1 | In Stock | ₹ 17,668.14 |
NB017717 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,668.14
GST (18%): ₹ 3,180.265
Total Price: ₹ 20,848.405
Antigen
L-Selectin/CD62L
Classification
Monoclonal
Concentration
1.0 mg/mL
Dilution
Flow Cytometry 1:50-1:100, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Accession No.
P14151
Gene Symbols
SELL
Immunogen
PHA stimulated lymphoblasts.
Quantity
0.025 mg
Primary or Secondary
Primary
Test Specificity
NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype
IgG2b
Applications
Immunohistochemistry (Frozen), Immunoprecipitation, Immunohistochemistry, Flow Cytometry
Clone
FMC46
Conjugate
Unconjugated
Formulation
Phosphate buffered saline with 0.09% Sodium Azide
Gene Alias
CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Gene ID (Entrez)
6402
Target Species
Bovine, Human, Primate, Canine
Form
Purified
Related Products
Description
- Description L-Selectin/CD62L Monoclonal specifically detects L-Selectin/CD62L in Human, Bovine, Canine, Primate samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Frozen.
Compare Similar Items
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Antigen: L-Selectin/CD62L
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry 1:50-1:100, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Accession No.: P14151
Gene Symbols: SELL
Immunogen: PHA stimulated lymphoblasts.
Quantity: 0.025 mg
Primary or Secondary: Primary
Test Specificity: NB100-65388 recognizes human CD62L, also known a L-selectin, a 74-95kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naive lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG2b
Applications: Immunohistochemistry (Frozen), Immunoprecipitation, Immunohistochemistry, Flow Cytometry
Clone: FMC46
Conjugate: Unconjugated
Formulation: Phosphate buffered saline with 0.09% Sodium Azide
Gene Alias: CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM-1, LAM1LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 6402
Target Species: Bovine, Human, Primate, Canine
Form: Purified
Antigen: P-Selectin/CD62P
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry 1:50-1:100, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Accession No.: P16109
Gene Symbols: SELP
Immunogen: P-Selectin transfected 300.19 cells.
Quantity: 0.025 mg
Primary or Secondary: Primary
Test Specificity: NB100-65391 recognizes the P-Selectin cell surface antigen, a 140kD glycoprotein. P-Selectin is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. Clone Psel.KO.2.12 is reported to inhibit P-selectin-dependent adhesion between HL60 cells and P-selectin transfected COS cells.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Applications: Immunoprecipitation, Immunohistochemistry, Immunohistochemistry (Frozen), Flow Cytometry
Clone: Psel.KO.2.12
Conjugate: Unconjugated
Formulation: PBS (pH 7.4) with 0.09% Sodium Azide
Gene Alias: CD62P antigen, FLJ45155, PADGEMantigen CD62), selectin P (granule membrane protein 140kDa, antigen CD62)
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 6403
Target Species: Goat, Human, Sheep, Rat
Form: Purified
Antigen: HLA ABC
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry 1:50-1:100, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Accession No.: __
Gene Symbols: HLA-A
Immunogen: PHA activated human peripheral blood lymphocytes.
Quantity: 0.025 mg
Primary or Secondary: Primary
Test Specificity: NB100-65411 recognizes a monomorphic determinant on the human HLA Class I heavy chain. Epitope analysis has shown that this antibody binds in the alpha1 domain. MHC Class I is expressed by all nucleated cells. Recent studies have shown that this antibody may be able to induce apoptosis in activated but not resting T cells (1).
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG2b
Applications: Immunocytochemistry, Immunohistochemistry, Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: YTH862.2
Conjugate: Unconjugated
Formulation: Phosphate buffered saline with 0.09% Sodium Azide
Gene Alias: A-10 alpha chain, FLJ26655, HLA class I histocompatibility antigen, A-1 alpha chain, HLA class I histocompatibility antigen, A-28 alpha chain, HLA class I histocompatibility antigen, A-9 alpha chain, HLAA, major histocompatibility complex, class I, A, MHC class I antigen A*1, MHC class I antigen A*11, MHC class I antigen A*80
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Gene ID (Entrez): 3105
Target Species: Human
Form: Purified