NB018083
Cytokeratin 8/18 Antibody (5D3), Novus Biologicals™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB018083-Each-of-1 | In Stock | ₹ 23,852.00 |
NB018083 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,852.00
GST (18%): ₹ 4,293.36
Total Price: ₹ 28,145.36
Antigen
Cytokeratin 8/18
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
Tissue culture supernatant, containing less than 0.1% sodium azide with Sodium Azide
Gene Symbols
KRT8
Immunogen
Cytokeratins from the human breast carcinoma cell line MCF-7.
Quantity
0.25 mL
Research Discipline
Cancer, Cytoskeleton Markers
Gene ID (Entrez)
3856
Target Species
Human
Form
Supernatant
Applications
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone
5D3
Dilution
Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500
Gene Alias
CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
Host Species
Mouse
Purification Method
Tissue culture supernatant
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This antibody is specific to human cytokeratins 8 (52.5 kDa) and 18 (45 kDa). It stains simple and glandular epithelium. It can be useful for the identification of adenocarcinomas and most squamous cell carcinomas.
Content And Storage
Store at 4°C.
Isotype
IgG1
Description
- Cytokeratin 8/18 Monoclonal specifically detects Cytokeratin 8/18 in Human, Mouse samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: Cytokeratin 8/18
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Tissue culture supernatant, containing less than 0.1% sodium azide with Sodium Azide
Gene Symbols: KRT8
Immunogen: Cytokeratins from the human breast carcinoma cell line MCF-7.
Quantity: 0.25 mL
Research Discipline: Cancer, Cytoskeleton Markers
Gene ID (Entrez): 3856
Target Species: Human
Form: Supernatant
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: 5D3
Dilution: Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500
Gene Alias: CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
Host Species: Mouse
Purification Method: Tissue culture supernatant
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This antibody is specific to human cytokeratins 8 (52.5 kDa) and 18 (45 kDa). It stains simple and glandular epithelium. It can be useful for the identification of adenocarcinomas and most squamous cell carcinomas.
Content And Storage: Store at 4°C.
Isotype: IgG1
Antigen:
Cytokeratin 8/18
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Tissue culture supernatant, containing less than 0.1% sodium azide with Sodium Azide
Gene Symbols:
KRT8
Immunogen:
Cytokeratins from the human breast carcinoma cell line MCF-7.
Quantity:
0.25 mL
Research Discipline:
Cancer, Cytoskeleton Markers
Gene ID (Entrez):
3856
Target Species:
Human
Form:
Supernatant
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
5D3
Dilution:
Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500
Gene Alias:
CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8
Host Species:
Mouse
Purification Method:
Tissue culture supernatant
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This antibody is specific to human cytokeratins 8 (52.5 kDa) and 18 (45 kDa). It stains simple and glandular epithelium. It can be useful for the identification of adenocarcinomas and most squamous cell carcinomas.
Content And Storage:
Store at 4°C.
Isotype:
IgG1
Antigen: IgM
Classification: Polyclonal
Conjugate: Unconjugated
Formulation: None, containing less than 0.1% sodium azide with Sodium Azide
Gene Symbols: IGHM
Immunogen: IgM isolated from human serum of a patient.
Quantity: 0.25 mL
Research Discipline: Immunology
Gene ID (Entrez): 3507
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Immunohistochemistry
Clone: __
Dilution: Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:150-1:250
Gene Alias: AGM1, DKFZp686I15196, DKFZp686I15212, FLJ00385, immunoglobulin heavy constant mu, MGC104996, MGC52291, MU, VH
Host Species: Rabbit
Purification Method: Affinity purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This antibody reacts with the mu-chains of human IgM. Nonspecific antibodies have been removed by solid-phase adsorption.
Content And Storage: Store at 4°C.
Isotype: IgG
Antigen:
IgM
Classification:
Polyclonal
Conjugate:
Unconjugated
Formulation:
None, containing less than 0.1% sodium azide with Sodium Azide
Gene Symbols:
IGHM
Immunogen:
IgM isolated from human serum of a patient.
Quantity:
0.25 mL
Research Discipline:
Immunology
Gene ID (Entrez):
3507
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Immunohistochemistry
Clone:
__
Dilution:
Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:150-1:250
Gene Alias:
AGM1, DKFZp686I15196, DKFZp686I15212, FLJ00385, immunoglobulin heavy constant mu, MGC104996, MGC52291, MU, VH
Host Species:
Rabbit
Purification Method:
Affinity purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This antibody reacts with the mu-chains of human IgM. Nonspecific antibodies have been removed by solid-phase adsorption.
Content And Storage:
Store at 4°C.
Isotype:
IgG
Antigen: Integrin alpha 4/CD49d
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: PBS with 0.09% Sodium Azide
Gene Symbols: ITGA4
Immunogen: JM leukaemia line (Human).
Quantity: 0.025 mg
Research Discipline: Cancer, Cellular Markers, Cytoskeleton Markers
Gene ID (Entrez): 3676
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone: HP2/1
Dilution: Flow Cytometry 1ug/5 x 10^5 cells, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias: 269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Mouse anti Human CD49d monoclonal antibody, clone HP2/1 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ∼150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer's patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). Mouse anti human CD49d, clone HP2/1 binds to both intact and the 80kDa fragment of integrin alpha-4. CD49d is expressed on monocytes, T cells, B cells, thymocytes and Langerhans cells (de Graaf et al. 1995). Mouse anti Human CD49d, clone HP2/1 can be used in basic studies of VLA-4 mediated adhesion and its interaction with the VCAM-1 structure and has been demonstrated to inhibit cell binding to soluble VCAM-1 (Weller et al. 1991).
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Antigen:
Integrin alpha 4/CD49d
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
PBS with 0.09% Sodium Azide
Gene Symbols:
ITGA4
Immunogen:
JM leukaemia line (Human).
Quantity:
0.025 mg
Research Discipline:
Cancer, Cellular Markers, Cytoskeleton Markers
Gene ID (Entrez):
3676
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation
Clone:
HP2/1
Dilution:
Flow Cytometry 1ug/5 x 10^5 cells, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Alias:
269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Mouse anti Human CD49d monoclonal antibody, clone HP2/1 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha. CD49d is a ∼150kDa single pass type 1 transmembrane glycoprotein with seven FG-GAP repeats, characteristic of alpha integrins, in its extracellular domain. CD49d can be proteolytically cleaved to yield framents of 80 and 70kDa (Hemler et al. 1987). CD49d associates with either CD29 to form VLA-4 or with Integrin beta-7 to form The Peyer patches-specific homing receptor LPAM-1, involved in the lymphocyte migration and homing to gut-associated lymphoid tissue (Sackstein 2006) through its interaction with MadCam-1, preferentially expressed on Peyer's patch high endothelial venules and postcapillary venules in lamina propria (Briskin et al. 1997). Mouse anti human CD49d, clone HP2/1 binds to both intact and the 80kDa fragment of integrin alpha-4. CD49d is expressed on monocytes, T cells, B cells, thymocytes and Langerhans cells (de Graaf et al. 1995). Mouse anti Human CD49d, clone HP2/1 can be used in basic studies of VLA-4 mediated adhesion and its interaction with the VCAM-1 structure and has been demonstrated to inhibit cell binding to soluble VCAM-1 (Weller et al. 1991).
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Antigen: RGS3
Classification: Polyclonal
Conjugate: Unconjugated
Formulation: PBS (pH 7.2), 1% BSA, 50% Glycerol with 0.02% Sodium Azide
Gene Symbols: RGS3
Immunogen: E. coli expressed human RGS 3 (amino acids 401-519).
Quantity: 0.025 mg
Research Discipline: Signal Transduction
Gene ID (Entrez): 5998
Target Species: Human
Form: __
Applications: Western Blot, Immunoprecipitation
Clone: __
Dilution: Western Blot, Immunoprecipitation
Gene Alias: C2PA, FLJ20370, FLJ31516, FLJ90496, PDZ-RGS3, regulator of G-protein signaling 3, regulator of G-protein signalling 3, RGP3
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Isotype: IgG
Antigen:
RGS3
Classification:
Polyclonal
Conjugate:
Unconjugated
Formulation:
PBS (pH 7.2), 1% BSA, 50% Glycerol with 0.02% Sodium Azide
Gene Symbols:
RGS3
Immunogen:
E. coli expressed human RGS 3 (amino acids 401-519).
Quantity:
0.025 mg
Research Discipline:
Signal Transduction
Gene ID (Entrez):
5998
Target Species:
Human
Form:
__
Applications:
Western Blot, Immunoprecipitation
Clone:
__
Dilution:
Western Blot, Immunoprecipitation
Gene Alias:
C2PA, FLJ20370, FLJ31516, FLJ90496, PDZ-RGS3, regulator of G-protein signaling 3, regulator of G-protein signalling 3, RGP3
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Isotype:
IgG