NB10056596W
ROCK1 Antibody (154C1465), Alexa Fluor™ 405 - (active/cleaved), Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB10056596W-Each-of-1 | In Stock | ₹ 53,218.32 |
NB10056596W - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,218.32
GST (18%): ₹ 9,579.298
Total Price: ₹ 62,797.618
Antigen
cleaved ROCK1
Classification
Monoclonal
Conjugate
Alexa Fluor 405
Formulation
50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias
EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.
Content And Storage
Store at 4C in the dark.
Isotype
IgG
Applications
Western Blot, Immunocytochemistry, Immunofluorescence
Clone
154C1465
Dilution
Western Blot, Immunocytochemistry/Immunofluorescence
Gene Accession No.
O60259
Gene Symbols
ROCK1
Immunogen
This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to amino acids 1114-1126 GNLPESRIEGWLS of human ROCK-1. This sequence is 100% conserved between human, chimpanzee, mouse, rat, dog, and rabbit. This immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1.
Quantity
0.1 mL
Research Discipline
Apoptosis, Breast Cancer, Cancer, Signal Transduction, Wnt Signaling Pathway
Gene ID (Entrez)
6093
Target Species
Human, Mouse, Rat, Canine, Primate, Rabbit
Form
Purified
Related Products
Description
- ROCK1 Monoclonal specifically detects ROCK1 in Human, Mouse, Rat, Canine, Primate, Rabbit samples
- It is validated for Western Blot, Immunocytochemistry/Immunofluorescence.
Compare Similar Items
Show Difference
Antigen: cleaved ROCK1
Classification: Monoclonal
Conjugate: Alexa Fluor 405
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias: EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.
Content And Storage: Store at 4C in the dark.
Isotype: IgG
Applications: Western Blot, Immunocytochemistry, Immunofluorescence
Clone: 154C1465
Dilution: Western Blot, Immunocytochemistry/Immunofluorescence
Gene Accession No.: O60259
Gene Symbols: ROCK1
Immunogen: This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to amino acids 1114-1126 GNLPESRIEGWLS of human ROCK-1. This sequence is 100% conserved between human, chimpanzee, mouse, rat, dog, and rabbit. This immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1.
Quantity: 0.1 mL
Research Discipline: Apoptosis, Breast Cancer, Cancer, Signal Transduction, Wnt Signaling Pathway
Gene ID (Entrez): 6093
Target Species: Human, Mouse, Rat, Canine, Primate, Rabbit
Form: Purified
Antigen:
cleaved ROCK1
Classification:
Monoclonal
Conjugate:
Alexa Fluor 405
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias:
EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG
Applications:
Western Blot, Immunocytochemistry, Immunofluorescence
Clone:
154C1465
Dilution:
Western Blot, Immunocytochemistry/Immunofluorescence
Gene Accession No.:
O60259
Gene Symbols:
ROCK1
Immunogen:
This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to amino acids 1114-1126 GNLPESRIEGWLS of human ROCK-1. This sequence is 100% conserved between human, chimpanzee, mouse, rat, dog, and rabbit. This immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1.
Quantity:
0.1 mL
Research Discipline:
Apoptosis, Breast Cancer, Cancer, Signal Transduction, Wnt Signaling Pathway
Gene ID (Entrez):
6093
Target Species:
Human, Mouse, Rat, Canine, Primate, Rabbit
Form:
Purified
Antigen: cleaved ROCK1
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias: EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.
Content And Storage: Store at 4C in the dark.
Isotype: IgG
Applications: Western Blot, Immunocytochemistry, Immunofluorescence
Clone: 154C1465
Dilution: Western Blot, Immunocytochemistry/Immunofluorescence
Gene Accession No.: O60259
Gene Symbols: ROCK1
Immunogen: This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to amino acids 1114-1126 GNLPESRIEGWLS of human ROCK-1. This sequence is 100% conserved between human, chimpanzee, mouse, rat, dog, and rabbit. This immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1.
Quantity: 0.1 mL
Research Discipline: Apoptosis, Breast Cancer, Cancer, Signal Transduction, Wnt Signaling Pathway
Gene ID (Entrez): 6093
Target Species: Human, Mouse, Rat, Canine, Primate, Rabbit
Form: Purified
Antigen:
cleaved ROCK1
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias:
EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG
Applications:
Western Blot, Immunocytochemistry, Immunofluorescence
Clone:
154C1465
Dilution:
Western Blot, Immunocytochemistry/Immunofluorescence
Gene Accession No.:
O60259
Gene Symbols:
ROCK1
Immunogen:
This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to amino acids 1114-1126 GNLPESRIEGWLS of human ROCK-1. This sequence is 100% conserved between human, chimpanzee, mouse, rat, dog, and rabbit. This immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1.
Quantity:
0.1 mL
Research Discipline:
Apoptosis, Breast Cancer, Cancer, Signal Transduction, Wnt Signaling Pathway
Gene ID (Entrez):
6093
Target Species:
Human, Mouse, Rat, Canine, Primate, Rabbit
Form:
Purified
Antigen: cleaved ROCK1
Classification: Monoclonal
Conjugate: Alexa Fluor 700
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias: EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.
Content And Storage: Store at 4C in the dark.
Isotype: IgG
Applications: Western Blot, Immunocytochemistry, Immunofluorescence
Clone: 154C1465
Dilution: Western Blot, Immunocytochemistry/Immunofluorescence
Gene Accession No.: O60259
Gene Symbols: ROCK1
Immunogen: This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to amino acids 1114-1126 GNLPESRIEGWLS of human ROCK-1. This sequence is 100% conserved between human, chimpanzee, mouse, rat, dog, and rabbit. This immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1.
Quantity: 0.1 mL
Research Discipline: Apoptosis, Breast Cancer, Cancer, Signal Transduction, Wnt Signaling Pathway
Gene ID (Entrez): 6093
Target Species: Human, Mouse, Rat, Canine, Primate, Rabbit
Form: Purified
Antigen:
cleaved ROCK1
Classification:
Monoclonal
Conjugate:
Alexa Fluor 700
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias:
EC 2.7.11, EC 2.7.11.1, MGC131603, MGC43611, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho kinase, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase 1
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG
Applications:
Western Blot, Immunocytochemistry, Immunofluorescence
Clone:
154C1465
Dilution:
Western Blot, Immunocytochemistry/Immunofluorescence
Gene Accession No.:
O60259
Gene Symbols:
ROCK1
Immunogen:
This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to amino acids 1114-1126 GNLPESRIEGWLS of human ROCK-1. This sequence is 100% conserved between human, chimpanzee, mouse, rat, dog, and rabbit. This immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1.
Quantity:
0.1 mL
Research Discipline:
Apoptosis, Breast Cancer, Cancer, Signal Transduction, Wnt Signaling Pathway
Gene ID (Entrez):
6093
Target Species:
Human, Mouse, Rat, Canine, Primate, Rabbit
Form:
Purified
Antigen: cleaved Retinoblastoma 1
Classification: Monoclonal
Conjugate: Alexa Fluor 405
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias: OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The antibody recognizes cleaved Rb (DRb-p70). The antibody does not recognize full-length Rb. In camptothecin treated HL60, an ∼68 kDa band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).
Content And Storage: Store at 4C in the dark.
Isotype: IgG1
Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), KnockDown
Clone: 172C1094
Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated
Gene Accession No.: __
Gene Symbols: RB1
Immunogen: A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb was used as immunogen.
Quantity: 0.1 mL
Research Discipline: Cancer, Cell Cycle and Replication, Transcription Factors and Regulators, Tumor Suppressors
Gene ID (Entrez): 5925
Target Species: Human, Mouse
Form: Purified
Antigen:
cleaved Retinoblastoma 1
Classification:
Monoclonal
Conjugate:
Alexa Fluor 405
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias:
OSRC, osteosarcoma, p105-Rb, pp110, pRb, Rb, retinoblastoma 1, retinoblastoma suspectibility protein, retinoblastoma-associated protein
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
The antibody recognizes cleaved Rb (DRb-p70). The antibody does not recognize full-length Rb. In camptothecin treated HL60, an ∼68 kDa band is observed. DRb-p70 exists in vivo as an N-terminally truncated form of Rb (Liu et al.). DRb-p70 is thought to be the product of alternative translation and is expressed in primary myeloid cells in fetal liver, bone marrow and spleen. DRb-p70 is also specifically expressed in tumor-associated macrophages (TAMs). TAMs are an important targets of cancer therapy. DRb-p70 is a marker of TAMs, and maybe useful for identifying tumors with macrophage infiltration (Liu et al, 2005).
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), KnockDown
Clone:
172C1094
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Knockdown Validated
Gene Accession No.:
__
Gene Symbols:
RB1
Immunogen:
A synthetic peptide corresponding to a region of the caspase-3-induced cleavage site of human Rb was used as immunogen.
Quantity:
0.1 mL
Research Discipline:
Cancer, Cell Cycle and Replication, Transcription Factors and Regulators, Tumor Suppressors
Gene ID (Entrez):
5925
Target Species:
Human, Mouse
Form:
Purified