Manufacturer: Fischer Scientific
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NB10063601-Each-of-1 | In Stock | ₹ 41,710.50 |
NB10063601 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,710.50
GST (18%): ₹ 7,507.89
Total Price: ₹ 49,218.39
LAG-3
Monoclonal
1.0 mg/mL
Flow Cytometry 1:50 - 1:200
CD223, CD223 antigen, FDC, LAG-3, lymphocyte activation gene 3 protein, lymphocyte-activation gene 3, Protein FDC
Rat
57 kDa
0.125 mg
Adaptive Immunity, Immunology, Innate Immunity
3902
Mouse
Purified
Flow Cytometry
C9B7W
Unconjugated
Q61790
LAG3
Murine CD223 Ig fusion protein
Protein G purified
RUO
Primary
NB100-63601 recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Clone C9B7W recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II (1). 1. Workman, C.J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol. 32 (8): 2255-63
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
IgG1